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38 Inhibitors of bacterial cell wall synthesis > Cephalosporins > Flashcards

Cephalosporins Flashcards

1
Q

Cephalosporins - groups

A

Generations 1-4 + advanced generation, cephamycins

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2
Q

Cephamycins (2 drugs)

A

Cefotetan

Cefoxitin

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3
Q

1st generation cephalosporins (2 drugs)

A

Cephalexin

Cefazolin

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4
Q

Cephalexin - indications

A

Skin & soft tissue inf

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5
Q

Cefazolin - indications

A

Perioperative prophylaxis

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6
Q

Cefotetan - indications

A

Intra-abdominal inf
Gynecological inf
Biliary tract inf

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7
Q

2nd generation cephalosporins (4 drugs)

A

Cefprozil
Cefuroxime
Cefotetan
Cefoxitin

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8
Q

Cefprozil and cefuroxime - indications

A

Respiratory tract, skin, soft tissue infections

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9
Q

Cefoxitin - indications

A

Surgical prophylaxis

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10
Q

3rd generation cephalosporins (4 drugs)

A

Ceftazidime
Cefpodoxime
Cefotaxime
Ceftriaxone

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11
Q

Ceftriaxone - indications

A

Gonorrhea, UTIs, otitis, meningitis, pneumonia, Lyme disease

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12
Q

Single dose treatment for gonorrhea (2 drugs)

A

Ceftriaxone

Cefpodoxime

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13
Q

Ceftazidime - indications

A

UTIs

Pneumonia

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14
Q

4th generation cephalosporin (1 drug)

A

Cefepime

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15
Q

Cefepime - indications

A

Intra-abdominal inf, UTI, pneumonia, skin & soft tissue inf

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16
Q

Cefepime - adverse effects

A

Encephalopahty

17
Q

Advanced-generation cephalosporin (1 drug)

A

Ceftaroline

18
Q

Ceftaroline - indications

A

Pneumonia, skin, soft tissue inf

19
Q

Cephalosporins - adverse effects

A

Hypersensitivity and cross-sensitivity with penicillins

20
Q

Cephalosporins - contraindications

A

Severe hypersensitivity to penicillin

21
Q

Cephalosporins associated with additional side effects (4 drugs)

A

Cefotetan
Cefmetazole
Cefamandole
Cefoperazone

22
Q

Cefotetan, cefmetazole, cefamandole, cefoperazone - adverse effects

A

Platelet dysfunction & bleeding

Disulfiram-like reaction with alcohol

23
Q

Can cephalosporins be used in pt with allergy to other betalactams?

A

No

38 Inhibitors of bacterial cell wall synthesis (5 decks)

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