Pelvic Masses Flashcards

1
Q

List non-gynae causes of pelvic mass

A

Bowel (constipation, caecal carcinoma, appendix abscess, diverticular abscess)
Bladder/urological (urinary retention, pelvic kidney)
Other e.g. retroperitoneal tumour

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2
Q

List gynae causes of pelvic mass

A

Uterine body
Cervix
Tubal and paratubal
Ovary

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3
Q

List causes of uterine pelvic mass

A
Fibroids
Endometrial cancer (usually PMB)
Cervical cancer (usually renal failure, bleeding, pain)
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4
Q

What is the commonest pelvic mass in females?

A

Fibroids (leiomyomas)

Benign smooth muscle tumours

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5
Q

List clinical features of uterine fibroids

A
Asymptomatic
Menorrhagia
Pelvic mass
Pain/tenderness
Pressure symptoms
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6
Q

Which investigations are appropriate if uterine fibroids are suspected?

A

Hb levels if heavy bleeding
Ultrasound usually diagnostic (smooth mass)
MRI for further localisation

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7
Q

What is the treatment for uterine fibroids?

A
Nothing if asymptomatic
Hysterectomy if family complete
Myomectomy
Uterine artery embolisation
Hysteroscopic resection
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8
Q

List some causes of fallopian tube swellings

A

Ectopic pregnancy
Hydrosalpinx: dilated fallopian tube due to obstruction
Pyosalpinx: dilated fallopian tube due to pus
Paratubal cysts

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9
Q

What finding on USS would suggest ectopic pregnancy?

A

Adnexal mass on USS

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10
Q

List types of ovarian mass

A

Benign tumours
Malignant tumours
Functional cysts
Endometriotic cysts

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11
Q

List clinical features of functional cysts

A

Related to ovulation (follicular, luteal)
Asymptomatic
Menstrual disturbance
Bleeding and pain if rupture

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12
Q

What is endometriosis?

A

Endometrial tissue in the wrong place (outwith uterus)

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13
Q

What is the typical appearance of endometriosis on the ovary on ultrasound? (buzzword)

A

Endometriomas/”chocolate cysts” filled with blood

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14
Q

List clinical features of endometriosis

A
Severe dysmenorrhoea
Premenstrual pain
Dyspareunia
Tender mass with nodularity
Tenderness behind uterus
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15
Q

List the main primary ovarian tumours that arise from surface epithelium

A
Serous
Mucinous
Endometrioid
Clear cell
Brenner
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16
Q

List the main primary ovarian tumours that arise from germ cells

A

Teratoma
Yolk sac tumour
Malignant germ cell tumour

17
Q

What is the commonest benign ovarian tumour?

A

Dermoid cyst (teratoma)

18
Q

How does a teratoma appear on XRAY?

A

Rim calcification
Fat inside
Tooth-like calcification

19
Q

What markers may be produced by malignant germ cell tumours?

20
Q

What can be some weird features of teratoma and why?

A

Teeth or hair growing where it shouldn’t

These are germ cell tumours derived from pleuripotent cells that can differentiate into anything

21
Q

List clinical features of ovarian cancer

A
Ascites/bloating
Pelvic mass
Bladder or bowel dysfunction
Pleural effusion
Breathlessness
Weight loss
Leg oedema or DVT
22
Q

Which genetic mutations increase the risk of ovarian cancer?

A
BRCA mutations (1 and 2)
Lynch mutations (HNPCC)
23
Q

List risk factors for ovarian cancer

A

Increasing age
Nulliparity
Family history

24
Q

Which investigations are appropriate if ovarian cancer is suspected?

A

Tumour markers
USS to determine nature of cyst
CT for identifying mets outwith the ovary

25
What tumour markers should be investigated for if there is suspected ovarian cancer?
Ca 125 | Carinoembryonic antigen
26
Normal levels of Ca 125 exclude ovarian cancer. True/False?
False
27
Measuring CEA is used to exclude what kind of ovarian cancer?
Exclude secondary metastasis from GI system
28
What is the "risk of malignancy index" calculation for diagnosing ovarian cancer?
Menopausal status x serum Ca 125 x ultrasound score | If elevated, refer to gynae team
29
How are ovarian cysts treated?
Removal or drainage if benign Removal of ovaries +/- uterus +/- omentum Chemotherapy prior to surgery Cure unlikely unless confined to ovary