Peer Teaching Mock 2 Questions Flashcards
1
Q
- What is the aim of the cervical cancer screening programme ?
A
- Screen for HPV
- Screen for abnormal cells indicative of pre-invasive (dyskaryosis) disease
2
Q
- How regularly are cervical screenings conducted ?
A
- Every 3 years in 25-49 year olds
- Every 5 years in 50-64 year olds
3
Q
- RFs for cervical cancer ?
A
- Multiple sexual partners
- Younger age at first intercourse
- Non-attendance at smears
- Immunosuppression
- Oral contraceptives
- Higher parity
- Tobacco use
- Deprivation
4
Q
- What would one see on speculum examination that could suggest malignancy ?
A
- Ulceration
- Visible mass
- Inflammation and bleeding
5
Q
- What are RFs for bacterial vaginosis ?
A
- Excessive vaginal cleaning
- Multiple sexual partners
- Smoking
- Recent antibiotic treatment
- Copper coli
6
Q
- How best should a 70 yo with urinary symptoms be investigated and why ?
A
- Urine culture and sensitivities
- NICE does not recommend doing urinary dipstick in women over the age of 65
7
Q
- What are the criteria of a CURB score ?
A
- Confusion
- Urea >7 (mmol/L)
- RR >30
- BP 90/60
- Age >65
8
Q
- What blood tests would be requested as part of a confusion screen ?
A
- FBC
- CRP/ESR
- Folate and B12
- U&Es
- HbA1c
- Calcium
- LFTs and TFTs
9
Q
- What is the most common type of leukaemia in children and what condition is it associated with ?
A
- Acute lymphoblastic leukaemia
- Down syndrome
10
Q
- What type of adult leukaemia is associated with the Philadelphia chromosome ?
A
- Chronic myeloid leukaemia
11
Q
- What leukaemia is associated with Auer Rods and Blast cells ?
A
- Acute myeloid leukaemia
12
Q
- What genetic mutation is the Philadelphia chromosome ?
A
- Translocation of chromosomes 9 and 22
13
Q
- How should leukaemia be investigated ?
A
- FBC
- Peripheral blood film
- Bone marrow biopsy
14
Q
- What is a common complication of treatment of chemotherapy for leukaemia ?
A
- Tumour lysis syndrome
15
Q
- What is the age of incidence of leukaemia ?
A
ALL: 0-14
- AML: 14-39
- CML: 40-59
- CLL : 60+
16
Q
- Hyperthyroid signs
A
- Fine tremor
- Palmar erythema/warm sweaty hands
- Tachycardia
- Atrial fibrillation
- Pretibial myxedema
- Lid retraction/lid lag
- Exophthalmos
- Acropachy
17
Q
- What is the most serious side effect of carbimazole ?
A
- Bone marrow suppression leading to pancytopenia and agranulocytosis
18
Q
- What signs might suggest a patient is suffering from bone marrow suppression secondary to carbimazole ?
A
- Bruising
- Mouth ulcers
- Sore throat
- Fever
- Malaise
- Non-specific illness
19
Q
- RFs for placental abruption ?
A
- PMHx
- Pre-eclampsia
- Abnormal lie of baby
- Age of mother > 40
- Abdominal trauma
- Smoking or cocaine use
- Multiple pregnancy
- Gestational diabetes
20
Q
- What are differentials for placental abruption ?
A
- Placenta praevia
- (Vasa praevia)
21
Q
- What are features of an Apgar score ?
A
- Appearance/body colour
- Pulse rate
- Grimace/reflex irritability
- Activity/muscle tone
- Respiratory effort
22
Q
- What are activities of daily living ?
A
- Bathing/shower
- Toileting
- Getting dressed/grooming
- Walking
- Eating meals/feeding
- Transferring/moving from bed to chair/standing from sitting
23
Q
- Which type of laxatives should be avoided in constipation secondary to opioid induced ?
A
- Bulk forming e.g. ispaghula husk
24
Q
- What laxatives should be offered for opioid induced constipation ?
A
- Osmotic e.g. Laxido or macrogol
- And stimulant laxative e.g. senna
25
Q
- What are symptoms of issues of urinary voiding ?
A
- Hesitancy
- Weak or intermittent stream
- Splitting
- Spray
- Straining
- Incomplete emptying
- Terminal dribbling
26
Q
- What are symptoms of issues of urinary storage ?
A
- Urgency
- Frequency
- Nocturia
- Incontinence
27
Q
- Which validated screening tool is used to evaluate LUTS and give a symptom score?
A
- International prostate symptom score ?
28
Q
- 1st line investigation for prostate cancer ?
A
- Used to be biopsy but is now multiparametric MRI
29
Q
- What is the most common site of prostate cancer metastasis ?
A
- Bone
30
Q
- What is the name for when a child becomes irritable, struggles with his breathing, and then his lips turn blue ?
A
- Tet spells
31
Q
- What anatomical abnormalities make up TOF ?
A
- Pulmonary stenosis
- Right ventricular hypertrophy
- Ventricular septal defect
- Overriding aorta
32
Q
- What pregnancy test would you offer to a women to screen for Down’s syndrome ?
A
- Combined test
33
Q
- What would suggest Down’s on a combined test ?
A
- Thickened nuchal translucency
- Reduced PAPPA
- Raised beta-HCG
34
Q
- What test would you offer a pregnant woman to confirm Down’s
diagnosis from the screening tests during pregnancy?
A
- Chronic villus sampling
- Amniocentesis
35
Q
- What medication can be used in polycystic kidney disease ?
A
- Tolvaptan
36
Q
- What symptoms would suggest smoke inhalation ?
A
- Burning sensation in nose or throat
- Productive cough
- Stridor, dyspnoea and SOB
- Wheezing, horse voice
- Cyanosis
- Tachypnoea
37
Q
- What effect does carbon monoxide have on the oxyhaemoglobin dissociation curve and how does this cause symptoms of carbon monoxide poisoning?
A
- Carbon monoxide has a greater affinity for haemoglobin than oxygen (so readily
- binds to Hb)
- Causing the curve to shift to the left
- Left shift → increased affinity of haemoglobin for oxygen / so haemoglobin holds onto
- oxygen more tightly
- Reducing the release of oxygen to tissues, causing hypoxia and the associated symptoms
38
Q
- What is the definition of a hernia ?
A
- Protrusion of part or whole of an organ or tissue through the wall of the cavity that normally contains it
39
Q
- What is the difference between a direct and indirect inguinal hernia ?
A
- Direct inguinal hernias – the bowel enters the inguinal canal directly through a weakness in the posterior wall of the canal whereas indirect hernias the bowel enters the inguinal canal via the deep inguinal ring
40
Q
- What are common types of hernia seen in infants
A
- Indirect inguinal hernia
- (Occur because of a) patent processus vaginalis
41
Q
- What are the complications of an incarcerated/irreducible hernia ?
A
- Obstruction and strangulation
42
Q
- What is the pathology of wet macular degeneration ?
A
- WET – neovascular – new choroidal blood vessels formation
- Leakage of serous fluid and blood which can result in rapid loss of vision
43
Q
- What medication and what route is wet macular degeneration managed ?
A
- Anti-vascular endothelial growth factor
- Intravitreal injection
44
Q
- What is the triad of shaken baby syndrome ?
A
- Retinal haemorrhages
- Subdural haematoma
- Encephalopathy
45
Q
- What are RA x-ray changes ?
A
- Loss of joint space
- Juxta-articular osteoporosis
- Soft-tissue swelling
- Periarticular erosions
- Subluxation
46
Q
- Typical features of RA presentation ?
A
- Swollen, painful joints in hands and feet
- Stiffness worse in the morning
- Gradually gets worse with larger joints becoming involved
- Presentation usually insidiously develops over months
- Positive squeeze test – discomfort on squeezing across the metacarpal or metatarsal joints
47
Q
- What are late features of RA ?
A
- Swan neck
- Boutonniere deformity
48
Q
- What is fine line antibody investigation for RA and which AB is more specific ?
A
- Rheumatoid factor
- Anti-CCP
49
Q
- What are the medical terms for a hip replacement ?
A
- Total hip arthroplasty
- Hemiarthroplasty
50
Q
- Name 3 features of skin lesions that are suggestive of chronic plaque psoriasis ?
A
- Raised clearly defined plaques
- Found on the extensor surfaces/elbows + knee/trunk/scalp
- Symmetrically distributed
- Pink or red erythematous violet or grey in pigmented skin
- Silvery scales
- Itch
- Auspitz sign – pinpoint bleeding if scale removed
51
Q
- Which type of psoriasis presents with a ‘’rain drop appearance’’ – multiple small scattered scaly papules ?
A
- Guttate psoriasis
52
Q
- Reasons to refer to a dermatologist for psoriasis ?
A
- Suspected generalised pustular psoriasis (emergency)
- Suspected erythrodermic psoriasis (emergency)
- Uncertainty about diagnosis
- Extensive involvement (more than 10%)
- Moderate or severe disease
- Resistance to topical drug treatments in primary care
- Significant impact on physical, psychological or social wellbeing
53
Q
- What is the difference between the terms ‘oligoarthritis’ and ‘polyarthritis’ ?
A
- Oligoarthritis affects 4 joints for fewer
- In polyarthritis more than 4 joints are involved
54
Q
- Nail signs for psoriatic arthritis
A
- Nail pitting
- Onycholysis
55
Q
- Name the difference between mania and hypomania ?
A
- Mania must have lasted for at least 6 weeks whereas in hypomania they only have to lasted for 4 days
- A manic episode includes psychotic features (delusions/hallucinations)
- A manic episode is severe enough to cause marked impairment in social or occupation functioning or necessitate hospitalisation
56
Q
- What is section 4 of the mental health act ?
A
- Allows the emergency detainment for the purpose of assessment for a duration of up to 72 hours
- The application can be made by the nearest relative or an Approved Mental Health Professional and must be supported by one doctor
57
Q
- When is lithium monitored when initiating treatment ?
A
- Weekly until concentrations are stable
58
Q
- How long after taking a dose should lithium levels be checked ?
A
- 12 hours post-dose
59
Q
- What 2 serological markers are used initially in Hep B screening ?
A
- HBsAg
- Anti-HBc
60
Q
- What serological marker gives a direct count of viral load ?
A
- HBV DNA
61
Q
- What is injected in Hep B vaccine ?
A
- HBsAg
62
Q
- Which forms of hepatitis can be vaccinated against ?
A
- Hep B
- Hep A
63
Q
- What investigations should a patient have post seizure ?
A
- EEG
- MRI head
- Blood glucose
- FBC U&Es
64
Q
- What are gout crystals composed of ?
A
- Monosodium urate
65
Q
- What are pseudogout crystals composed of ?
A
- Calcium pyrophosphate
66
Q
- 1st line for acute gout ?
A
- NSIADs or colchicine
67
Q
- 1st line and 2nd to prevent gout attacks ?
A
- Allopurinol (Xanthine oxidase inhibitor)
- Febuxostat