PedsLungsBloodCancerSkin Flashcards

1
Q

What’s involved in a respiratory assessment in peds?

Additional considerations for children?

A

Rate, rhythm, and ease: the work of breathing.
Infection: symptoms, age, size, seasons, decreased resistance
Infants are obligate nose breathers, small airways, large tongues.
Older children have large tonsils and adenoids.

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2
Q

Common peds respiratory testing?

A

Pulmonary function tests (PFTs), bronchoscopy, nasopharyngeal wash, apnea-bradycardia monitors, pulse ox

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3
Q

7-10 days duration, clear to yellow thin nasal secretions. Hoarseness with sore throat, dry cough.

A

Nasopharyngitis, the common cold. Fatigue, decreased appetite, +/- fever. Can be complicated by secondary bacterial infections. Symptomatic relief. Care with combination cold remedies.

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4
Q

What should the family be taught for URIs?

A

Recognize worsening symptoms. Prolonged or new fever, increased throat pain or lymphadenitis, worsening cough or one lasting longer than 10 days, chest pain, dyspnea, earache, headache, sinus pain, irritability.

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5
Q

When is it sinusitis instead of a cold?

A

Cold symptoms not improving after 7-10 days. New onset fever and/or cough. Halitosis, eyelid edema, facial pain may be present but is a poor indicator.

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6
Q

Inflammation of the pharynx or tonsils (tonsillitis. Abrupt onset, often dysphagia, fever, HA, abdominal pain. Inspect for what?

A

Pharyngitis, sore throat.

Exudate, petechiae on the palate, strawberry tongue, lymphadenitis, scarlatiniform rash.

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7
Q

Viral vs bacterial pharyngitis? Diagnosis?

A

Viral occurs with cold s/s. It’s self-limited, only symptomatic care.
Bacterial occurs without nasal symptoms, just the throat itself: Group A strep (strep throat). Needs treatment with penicillin for 10 days.
Diagnosis is made only by throat culture, not inspection.

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8
Q

Viral in nature. Inflammation, edema, mucus obstruct the airway. Hoarseness, barky cough. Occurs suddenly, at night.

A
Laryngotracheobronchitis.
Young child (3 months to 3 years). Treated with humidified air in shower or cold air.
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9
Q

Symptoms for acute otitis media? Past medical history?

A

Fever, tugging at ears, night awakening, otalgia, fluid draining from the ear, fussiness, poor feeding, crying lying down.
PMH includes young age, dat care attendance, previous AOM or OME, recent URIs

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10
Q

Risk factors for acute otitis media?

A

Crowded living, daycare attendance, 1st episode of AOM before the age of 3 months, exposure to passive smoking, not having been breastfed, craniofacial abnormalities, possibly allergies

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11
Q

Complications of AOM? Either AOM or OME complications?

A

AOM: acute mastoiditis, intracranial infections, tympanosclerosis, tympanic membrane perforation.
Either: hearing loss, expressive speech delay

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12
Q

Inflammation of the bronchioles cause by viruses, such as the respiratory syncytial virus (RSV). Clear runny nose gets progressively worse in 1-3 days. Asthma like: coughing, fever, wheezing.

A

Acute lower tract infection: bronchiolitis.
Low pulse ox due to edema of the bronchioles. Tachypnea.
Diagnosed with a nasopharyngeal wash, chest XR that shows atelectasis, collapsed alveoli.

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13
Q

Treatment of bronchiolitis?

A

Symptomatic based, doesn’t need antibiotics. Suctioning, antipyretics, asthmatic medications (bronchodilators). Home care: fluid, suctioning. Hospitalization.

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14
Q

Prevention of bronchiolitis?

A

Strict hand washing in day care and homes, droplet and contact precautions.
Certain populations: palivizumab vaccine (Synagis),

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15
Q

Risks for bronchiolitis?

A

Crowded living, children under 2, older siblings in school, heart and respiratory disease, not being breastfed, reasons of RSV, premature.

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16
Q

Viral vs bacterial pneumonia?

A

Viral they may look okay, be active.
Bacterial they look sick. Abrupt onset often after a URI. When they appear ill: feel, tachypnea, cough, chest pain, malaise. Often present with fever and ab pain.

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17
Q

Risk factors for foreign post aspiration? S/s?

A

Small airways and kids, Ages 6 months to 4 years old, especially ages 1-3. Boys. Being mobile and exploration, developmental delay, uneducated parents.
S/s can be sudden, cough at first with cyanosis later. Wheezing, stridor (could go into lungs and then have no symptoms, leads to aspiration pneumonia and swelling). Fever.

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18
Q

Associated with atopic dermatitis, asthma, recurrent sinusitis, AOM.

A
Allergic rhinitis (runny nose caused by allergies). 
Perennial is year round and indoor environments. Pets, dust mites, cockroach antigens, molds. 
Seasonal is different seasons and outdoor elements, pollens, trees, weeds, fungi, molds.
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19
Q

Chronic, reversible inflammatory airway disorder. Airway is hyper-reactive to triggers, causing obstruction and bronchoconstriction. Mild intermittent and mild persistent?

A

Asthma.
Mild intermittent: Symptoms < twice/week. Nocturnal < twice/month. Pulmonary function > 80% normal
Mild persistent. Symptoms > twice/week, not daily. Nocturnal > twice/month. Pulmonary function > 80% normal

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20
Q

Moderate persistent and severe persistent asthma?

A

Moderate persistent: Symptoms daily. Nocturnal > 1/week. Pulmonary function 60-80% normal
Severe persistent: Symptoms continuous, frequently at night, activity limitations. Pulmonary function < 60% normal

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21
Q

How does one use a peak flow meter?

A

Set the arrow on the meter to zero. Stand up straight. Deep breath with lips tightly around the meter. Blow out hard and fast. Repeat 3 times and record the highest.
Green is >80% of expected peak flow, yellow is 50-80, red is <50% of expected.

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22
Q

What does the peak flow reading mean?

A

Objective measurement of lung function. Child can learn to perform the test to help determine status of asthma. Can provide early identification of subtle symptoms. Early treatment can help to decrease risk of permanent lung changes (remodeling).

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23
Q

Rescue medications for asthma?

Prevention meds?

A

Rescue to treat acute symptoms and exacerbations. Short-acting beta 2 agonists such as Albuterol and Xopenex.
Prevention are long-term controller meds. Achieve and maintain control of the inflammation. Inhaled corticosteroids. Oral leukotriene modifiers.

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24
Q

Asthma med that dilates the smooth muscle, decreasing spasms. Side effects?

A

Short-acting beta 2 agonists for rescue in acute exacerbations. Side effects include increased heart rate, trouble sleeping, increased RR. All of these result in decreased adherence. Albuterol and levbuterol (has less cardiac effects than albuterol)

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25
Q

Decrease inflammation to treat reversible airflow obstruction. Control symptoms and reduce bronchial hyper- responsiveness. Lowest dose to avoid side effects.

A

Corticosteroids in acute exacerbations.

Prednisolone given orally. Solumedrol given IV for hospitalized patients.

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26
Q

Autosomal recessive disorder. Deletion of chromosome 7 is responsible gene mutation, causes dysfunction of the exocrine glands. Chloride transport across cells is interrupted so water transport abnormalities occur. Difficult for the body to clear secretions.

A

Cystic fibrosis. Recommended testing for women presenting for preconception or prenatal care, DNA testing done prenatally or on newborns.
Results in drier, thicker secretions in sweat glands, GI test, pancreas, repository, other exocrine tissues. High levels of chloride in sweat cause salty taste.

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27
Q

Further explain cystic fibrosis?

A

Pancreatic enzyme inactivity causes malabsorption, poor growth, fatty stools. Thick mucus plugs the small airways. Secondary bacterial infections with usual bugs. Leads to obstruction and inflammation leading to chronic infection, tissue damage, respiratory failure. S. aureus, p. auriginosa.

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28
Q

Pulmonary management of those with cystic fibrosis?

A

Minimizing pulmonary complications and maximizing lung function. Preventing infections with: daily chest physiotherapy when well, nebulizer pulozyme to decrease sputum viscosity, inhaled bronchodilators and anti-inflammatory meds, aerosolized antibiotics.

29
Q

Growth management of children with cystic fibrosis?

A

Supplemental water soluble vitamins (A, D, E, K). Pancreatic enzymes (pancrealipase, Creon) before every meal and snack. High calorie and high protein diets with additional G tube feeds for some at night. Some require TPN feeds.

30
Q

Health history of children with cystic fibrosis?

A

Meconium ileus, significant constipation, steatorrhea, poor weight gain despite eating well, chronic couch, activity intolerance.

31
Q

Sweat tests for diagnosis of cystic fibrosis?

A

Measurement of chloride in the skin. <40mg is negative. Repeat only if they have bulky, foul stools, FTT, recurrent respiratory infections. >60 is positive but must be repeated. Other disorders can cause a positive test.
Chest xr, PFTs, DNA or fecal fat testing

32
Q

Cystic fibrosis management?

A

CF clinic every 2-3 months. Monitoring of growth and development. Assess of lung function, pulmonary toiling with CPT or vest bid-qid. Antibiotics, bronchodilators, airway clearance. Assess of GI for malabsorption symptoms, pancreatic enzyme admin. Monitor for complications of treatment. Assess of psychosocial issues.

33
Q

Cystic fibrosis education?

A

Chest physiotherapy and postural drainage, proper caloric uptake and diet, correct use and cleaning of equipment, early signs of infection, complications, when to seek medical care.

34
Q

Absence of breathing for greater than 20 seconds.

A

Apnea. ALTE: some combination of apnea, color changes, muscle tone changes, coughing, gagging.

35
Q

What are the 3 types of RBC at birth?

A

Hgb F, fetal hemoglobin which is found during fetal development.
Hgb A is minor adult hemoglobin, found after birth.
Hgb A is normal adult hemoglobin
First made it the liver, then in the bone marrow of long bones

36
Q

The number one hematologic disorder of childhood. Decreased number of RBC’s. If it develops slowly then children adapt to it. Treatment is based on the underlying cause.

A

Anemia.

Caused by accidents, bleeding, poor nutrition, drinking too much milk, sickle cell anemia.

37
Q

Where is iron stored?

A

Fetal erythrocytes, liver, spleen, and bone marrow. Iron stores are adequate until about 4-6 months of age. By then the baby should be making their own HgbA with iron from food, supplements, formula, and cereal.

38
Q

Prevention of IDA (iron-deficiency anemia)?

A

Iron-fortified infant formula. Iron-fortified infant cereal, starting at 4-6 months for all infants, unless exclusively breastfeeding. Iron supplementation drops starting at 4-6 months for exclusively breastfed infants.

39
Q

Why are toddlers at risk for IDA? Who else?

A

Toddlers won’t eat or they’re having too much milk. Premature babies and teen girl are at risk, the teens because of menstruation. Long-term consequences include developmental delays.

40
Q

Treatment of IDA?

A

Iron rich foods are not enough once they’re anemic. Supplements for 3 months after Hgb normalizes. Watch absorption and administration considerations. Give vitamin C, give iron on an empty somtach

41
Q

Dosing of iron?

A

Based on elemental iron and how significant their deficiency is. Mild to moderate is 3mg/kg/day in 1-2 divided doses. Severe is 4-6 mg/kg/day in 3 doses.
Fer-in-sol is 75mg/0.6 ml (15mg elemental iron/0.6 ml)

42
Q

When under stress, the RBC is sickle-shaped (misshapen/elongated) and can clog vessels.

A

Sickle cell anemia. It’s a protective measure against malaria. African, Mediterranean, Indian, Middle Eastern. Autosomal recessive.

43
Q

Pathophysiology of sickle cell anemia (SCA)?

A

Sickling of RBC’s under stress. Clumping of abnormal shaped cells, causing vaso-occlusive crisis, splenic sequestration/destruction of RBCs, acute chest syndrome, stroke.

44
Q

S/s of SCA?

A

Asymptomatic until about 4-6 months of age. High Hgb S. Pale, slightly jaundiced with splenomegaly. Hgb is 5-9. Fever, ab and chest pain, painful swelling of hands and feet due to infarction.

45
Q

Management of SCA?

A

Pain, must be arrgresively manage and beloved. Hydration, blood transfusions, splenectomy, prevention of sickling, prevention of infections, treatment of infections and dehydration.
Prognosis used to be 20s-40s but now into the 50s and beyond. Greatest risk to children is infection.

46
Q

SCA complications?

A

Reduced visual acuity, leg ulcers, gallstones, poor growth and development, increased incidence of enuresis due to decreased kidney circulation.

47
Q

Inherited, the protein for clothing blood is reduced. Bleeding for longer than normal.

A

Hemophilia A, factor VIII deficiency (85%). Hemophilia B, factor IX deficiency (15%). Both are x-linked recessive so they affect males.
Von willebrand disease can affect women, it’s autosomal dominant.

48
Q

Mild, moderate, and severe hemophilia?

A

Mild have greater than 5% of factor VIII. Often not diagnosed until adulthood.
Moderate 1-5%. Bleed after injury, occasional spontaneous bleeds.
Severe is <1%. Bleed after injury, frequent spontaneous bleeds.

49
Q

Most common bleeding disorder, affecting 1-2% of the population.

A

Von Willebrand Disease (vW).

vW protein and a factor VIII deficiency. Varying amounts fo the vW protein determine severity.

50
Q

Medications for hemophilia or vW disease? Education?

A

Desmopressin (DDVAP, stimate), factor replacement.
Educate on bleeding, hemarthrosis, avoidance of obesity, electric razor, care with dental procedures, safe environment with careful supervision.

51
Q

Diagnostic tests for peds cancer?

A

Biopsy to identify, classify, and stage.
Bone marrow aspiration: iliac crest, sternum. Diagnosis and monitoring of the effectiveness of therapy.
Special tests include alpha-fetoprotein, VMA or HVA, elevated catecholamines

52
Q

Overproduction of abnormal white blood cells. Immature, abnormally functioning blast cells.

A

Leukemia. Fills the bone marrow with abnormal white cells. They spill into the blood and replace normal WBCs. Suppress the normal cell formation in bone marrow.

53
Q

Medications for bone marrow suppression?

A

Neupogen. SC or IV daily for up to 14 days, until the ANC is >10,000. Not given within 48 hours of chemo.
Erythropoietin, stimulates erythrocytes production. Epogen and Procrit, SC or IV three times a week. Dose adjusted based on the labs.

54
Q

Acute vs chronic leukemia?

A

Acute: ALL, immature lymphocytes. AML, immature myelocytes.
Chronic: CML, chronic leukemia, adult disease

55
Q

S/s of leukemia? Diagnosis?

A

S/s come from bone marrow suppression. Anemia, leucopenia, leukocytosis, thrombocytopenia.
Diagnosis is from bone marrow aspiration, looking for blast cells.

56
Q

Most common solid tumor. S/s?

A

Brain tumor. S/s are based n location, size, and the child’s age. Headache upon arising. Vomiting that’s unrelated to feeding. Will see balance deficiency, weakness, gait issues. Important to concentrate on neuro exam.

57
Q

Originates from nerve tissue. S/s? Diagnosis?

A

Neuroblastoma. Pain, depending on location it can compress organs such as the heart and the bladder. Ab or cerebral mass. Weight loss, pallor, symmetrical bruising.
Diagnosed with 24hr urine. Look for byproducts of the nervous system, like catecholamine.

58
Q

Cancer in the connective tissue, anywhere the muscles and bones are.

A

Rhabdomyosarcoma.
S/s depend on where it is, but show malignancy of skeletal muscle.
Maternal risk factors include weed, coke, and xr exposure in utero.

59
Q

S/s of retinoblastoma?

A

Leukocoria (cat’s eye). Originates in the retina.
Treatment involves enucleation, which is removal of the eye. Opthalmologic exams every 3 months after treatment. 95% cured.

60
Q

Wilm’s tumor-nephroblastoma?

A

Ab mass, firm, non-tender, confined to one side. Hematuria, HTN.
Dx is US, MRI
Do not palpate. May rupture easily.

61
Q

S/s of osteosarcoma, Ewing’s sarcoma?

A

Limp, pain, mass, fracture

62
Q

Variations in the skin of children?

A

Heat loss, higher absorption of substances due to thin skin. Higher water content can lead to blistering. Less pigmented means sunburns.

63
Q

Integumentary glands in children?

A

Sebaceous glands produce sebum to lubricate and waterproof the skin and hair, Contribute to the severity of acne.
Eccrine are gleeful in temp regulation through water evaporation. Found all over the body.
Appocrine glands mature during puberty, cause of body odor. Found in the hair follicles, mostly armpits and groin.

64
Q

Health promotion for sun protection in children?

A

No sun form 10am-4pm.
under 6 months minimal amount of sunscreen, spf greater than or equal 30 to small areas.
Older than 6 months same as younger but more liberal use of spf greater than or equal to 15.

65
Q

Appears between 2-4 weeks, lasting from 4-6 months. From maternal hormones, 20% of newborns.

A

Infantile acne. Wash daily with clear water, don’t pop. Reassurance of the mother.

66
Q

Most children are affected, males more so than females. Begins 7-10 years old, peaks 15-18 years. Face, chest, back. Patho?

A

Acne vulgaris.
Sebaceous gland connected to skin surface via follicular canal. Androgenous hormone increase sebaceous gland activity. Gland secretes sebum which clogs the hair follicle and causes a keratin plug. Keratin plug is good area for Proprionibacterium acnes infection to proliferate. Neutrophils go to the site of infection and cause inflammation. Contents of the clogged follicle spill over into nearby tissue. Inflammation causes large cysts to form, then scarring of skin

67
Q

Acne vulgarism treatment goals?

A

Decrease the cause: bacteria, sebum production, inflammation.
Focus on general health, including diet, stress, rest. Cleaning, remember hair and scalp. Mild cleanser on the face twice daily with non-clogging soap

68
Q

Acne medication that inhibits microcomedones.

A

treitonoin, Retin-A.

Use pea sized amount 20 minutes after washing. Use sunscreen. Onset and peak are 2/6 weeks