Peds & Strabismus Flashcards
Corneal light reflex tests should be used to evaluate binocular alignment for what patients?
Patients with poor vision in one or both eyes (can’t fixate). Unable to cooperate to allow cover testing or poor vision with poor fixation.
Hirschberg method
Corneal light reflex based on premise - 1 mm of decentration corresponds to 7 degrees or 15 diopters of ocular deviation of the visual axis.
Krimsky method
corneal light reflex test - reflections produced on both corneas by penlight at near fixation
Bruckner
direct ophthalmoscope to obtain red reflex simultaneously in both eyes
Major amblyoscope method
corneal light reflex test uses separate target illumination which can be moved to center the cornea light reflection, deviation read off of scale
In what cardinal position is the left superior oblique muscle the prime mover
down to the right
Cardinal positions
prime mover is 1 muscle of each eye, together called yoke muscles. 6 cardinal positions
9 diagnostic positions of gaze
6 cardinal positions plus straight up and down and primary
Draw the 6 cardinal positions of gaze and the prime movers
2 o’clock: LSR, RIO 3 o’clock: LLR, RMR 5 o’clock: LIR, RSO 7 o’clock: RIR, LSO 9 o’clock: RLR, LMR 11 o’clock: RSR, LIO
Syndromes a/w ocular-cutaneous albinism
Chediak-Higashi syndrome Hermansky-Pudlak
AR disorder with mutation in lysosomal trafficking regulator protein that renders inadequate phagocytosis, pyogenic infections involving respiratory and cutaneous sx. Rarely survive past 10 years
Chediak-Higashi
AR disorder characterized by ocular-cutaneous albinism, bleeding problems from platelet abnormality
Hermansky-Pudlak syndrome
Iris transillumination defects, fundus hypopigmentation, decreased melanin distribution in the RPE and choroidal tissue
Ocular albinism
Infant aphakia treatment study group finidng
IOL implantation in infants age 1 to 6 months is a/w higher rates of adverse events requiring furter surgery and no better grating acuity at 1 year
Greatest risk for isoametropic amblyopia
Astigmatism
Features of brain scan and CSF in child with IIH
NORMAL sized or SMALL ventricles Normal CSF
risk factors for IIH
viral infections, drug use (tetracycline, corticosteroids, vitamin A, nalidixic acid, thyroid medications, GH), central venous sinus thrombosis
Feature characteristic of congenital ptosis
decreased levator function poorly formed eye crease Results from dystrophic development of levator withotu innervational abnormalities
Length of lid tissues and levator in congenital ptosis
Not longer than normal
M/c blockage location in congenital NLDO
valve of hasner
What genetic disorder is congenital iris ectropion most commonly seen in
NF1 Also seen in prader-willi syndrome or facial hemihypertrophy
Corneal crystals
cystinosis
Eye movement abnormality can occur in healthy infants in first months of life
intermittent esotropia
Epiblepharon
congenital anomaly with horizontal fold of skin adjacent to lower eyelid, causing inward rotation of lashes against cornea (occurs in chubby cheek and asians)
Eversion of eyelid margin secondary to vertical deficiency of skin
congenital ectropion
enlargement of lateral aspect of palpebral fissure with downward displacement of temporal half of lower eyelid
Euryblepharon
Age at which infant maintains fixation and reacts with facial expressions
6-8 weeks
Age interested in bright objects
2-3 months
Age at which nasal bias for smooth pursuit should have resolved, eyes orthotropic and fix-and-follow response to small (2-4 inches in diameter) toy
3-4 months
Patient with sporadic aniridia must be evaluated for..
Wilms tumor with renal ultrasonography which must be repeated until molecular genetic analysis r/o 11p13 deletion and confirms an intragenic PAX6 mutation
Method recommended for assessing the refractive state in amblyopia
Cycloplegic retinoscopy
Congenital eyelid malformation that would require early repair
eyelid coloboma (eyelid cleft, eyelid notch) - risk of exposure keratopathy
Preferred surgical procedure to treat upshoots and downshoots in Duane syndrome
Y-splitting of lateral rectus muscle
Treatment for vision-threatening periocular hemangiomas
oral propranolol
Laboratory test that should be ordered for patient with enlarging infantile capillary hemangioma and Kasabach-Merritt syndrome
platelet count - sequestration of platelets within large vascular lesion such as hemangioma leading to thrombocytopenia
What is isoametropic amblyopia (b/l ametropic amblyopia)
bilateral decreased VA due to large approximately equal uncorrected refractive errors in the 2 eyes of child
Type of hyperopia and myopia that carry risk of inducing isoametropic amblyopia
Hyperopia exceeding 4.00 D-5.00D and myopia exceeding 5.00-6.00D
Type of amblyopia induced by capillary hemangioma
Anisometropic amblyopia - induces astigmatic refractive error (8 diopters of astigmatism)
What is anisometropic amblyopia?
Dissimlar refractive error in 2 eyes
Epiblepharon
condition in which the eyelid pretarsal muscle and skin ride above the eyelid margin to form a horizontal fold of tissue that causes the cilia to assume a vertical position
A pattern exotropia frequently a/w…
Superior oblique overation
V pattern exotropia frequently a/w…
Inferior oblique muscle overaction
When is A pattern considered clinically significant
difference between upgaze and downgaze is at least 10 PD
When is V pattern considered clinically significant
at least 15 prism diopters
Surgery that would most benefit an 18-month old child with V-pattern infantile esotropia and bilateral DVD
bilateral MR recessions and bilateral IO recessions
IO recession will address
V pattern and DVD
Leading cause of blindness in the word
cataract 48% of cases, glaucoma 12%
M/c strabismus in FAS
esotropia
FAS features
craniofacial - short palpebral fissures, telecanthus, strabismus (esotropia), ptosis, ON hypoplasia, tortuosity of retinal vessels
Most likely cause of chin up posture
V-pattern exotropia
Most likely cause of chin down posture
A-pattern exotropia
Occur in up to 1/4 of all horizontal strabismus cases
A-pattern or V-pattern strabismus
M/c mode of inheritance of NF1
AD (however 50% of patients have (-) FHx)
Following surgery for congenital cataract, what finding predisposes a child to glaucoma
Small corneal diameter (microcornea) or persistent fetal vasculature
M/c ocular finding in neonate with congenital rubella syndrome (CRS)?
Unilateral or bilateral pigmentary retinopathy (25%-50%) “salt-and-pepper” Cataract (15%) Glaucoma (10%)
5 yo F with 1-month h/o intermittent nasal discharge, tearing, itchy eyes, conjunctiival injection. Initial therapy?
Oral antihistamines - useful if nasal congestion less effective for ocular sx but better tolerated in children
Inheritance pattern for most patients with primary congenital glaucoma?
SPORADIC (rarely AR)
Finding of a DVD is a/w?
congenital strabismus
Pattern of strabismus a/w aberrant innervation of LR muscles in upgaze?
Y pattern (pseudo-overaction of inferior obliques)
Patient with A-pattern exotropia will adopt this head posture.
Chin down
For a paretic or restricted eye in fixation, what term describes the deviation of alignment?
SECONDARY - deviation measured when the paretic or restricted eye is fixating
What is the primary deviation?
deviation measured when the nonparetic eye is fixating.
What is a consecutive devation?
Strabismus that is in the direction opposite to one that the patient had originally.
Most common intraocular finding in NF1?
iris melanocytic nodules (Lisch nodules)
Diffuse choroidal hemangiomas found in this phacomatoses?
Sturge-Weber syndrome
Capillary hemangioblastomas of the retina or optic disc
von Hippel-Lindau syndrome
Preoperative test that is most helpful in assessing opportunity for single binocular vision after strabismus?
Amblyoscope - tests for retinal correspondence
Exodeviation that orthoptic exercises are most appropriate initial therapy for?
Convergence insufficiency
Draw Cardinal positions
CRS (25%-50%) variation from finely stippled, bone spicule-like, small, black, irregular masses to gross pigmentary irregularities with coarse, blotchy mottling. Stationary or progressive.
Epiblepharon
Capillary hemangioma - risk for anisometropic amblyopia
Ligneous conjunctivitis
V-pattern exotropia
Neurofibromas in NF1 m/c finding in eye would be iris melanocytic nodules (Lisch nodules)
Large-angle constant exodeviation before age 6 months
Infantile exotropia (XT)
Risks a/w infantile XT
neurologic impairment or developmental delay
Another name for Tuberous sclerosis complex
Bourneville-Pringle disease
Retinal astrocytic hamartomas are seen in this disease with what frequency?
Tuberous sclerosis (Boruneville-Pringle) in 40% of patients