Peds: Newborns-Toddlers Flashcards
Danger Signals
Failure to _____
D___ Syndrome
Fetal _____ Syndrome
(1) (Undescended Testicle)
G______ Ophtalmia Neonatorum
Ch_____ Ophthalmia Neonatorum (Trachoma)
Chlamydial Pn______
Sudden Infant ______ Syndrome
Excessive Weight Loss (>___%)
De______
Failure to Thrive
Down Syndrome
Fetal Alcohol Syndrome
Cryptorchidism (Undescended Testicle)
Gonococcal Ophtalmia Neonatorum
Chlamydial Ophthalmia Neonatorum (Trachoma)
Chlamydial Pneumonia
Sudden Infant Death Syndrome
Excessive Weight Loss (>10%)
Dehydration
Failure to Thrive
Defined as weight for age that falls below __-__ percentile for gestation-corrected age and gender when plotted on appropriate growth chart (on more than one occasion).
Also, infants whose rate of weight change decreases over ____ or more major percentile lines (90th, 75th, 50th, 25th, and 5th) exhibit failure to thrive (FTT; e.g., a child at the 50th percentile goes down to 5th percentile over a few months).
Use (1) charts until the age of 2 years, and then (1) growth charts.
In most cases seen in primary care, causes are usually inadequate di____ intake, dia____, mal______ (celiac disease, cystic fibrosis, food allergy), poor maternal b_____, frequent in_____, and others.
Defined as weight for age that falls below 3rd to 5th percentile for gestation-corrected age and gender when plotted on appropriate growth chart (on more than one occasion).
Also, infants whose rate of weight change decreases over two or more major percentile lines (90th, 75th, 50th, 25th, and 5th) exhibit failure to thrive (FTT; e.g., a child at the 50th percentile goes down to 5th percentile over a few months).
Use World Health Organization (WHO) growth charts until the age of 2 years, and then Centers for Disease Control and Prevention (CDC) growth charts.
In most cases seen in primary care, causes are usually inadequate dietary intake, diarrhea, malabsorption (celiac disease, cystic fibrosis, food allergy), poor maternal bonding, frequent infections, and others.
Down Syndrome
A genetic defect caused by tr____ of chromosome ___ (three copies instead of two). The most common chromosomal disorder; the average life span is ___ years in the United States.
Affected persons have a round face that appears “___” (decreased anterior–posterior diameter), accompanied by __ward-slanting eyes (palpebral fissures) and ___-set ears.
Chronic open mouth caused by enlarged ______ (macroglossia), accompanied by a ______ neck. ____ fingers, ____ palms, and a broad hand with transverse palmar crease (S____ crease) are additional signs.
Newborns have h____tonia and poor M____ reflex. Higher risk of int______ disability, congenital ____ defects (50%), feeding difficulties, congenital h______ loss, th____ disease, cataracts, sleep apnea, and early onset of A______ disease (average age 54 years).
A genetic defect caused by trisomy of chromosome 21 (three copies instead of two). The most common chromosomal disorder; the average life span is 60 years in the United States.
Affected persons have a round face that appears “flat” (decreased anterior–posterior diameter), accompanied by upward-slanting eyes (palpebral fissures) and low-set ears.
Chronic open mouth caused by enlarged tongue (macroglossia), accompanied by a shorter neck. Short fingers, small palms, and a broad hand with transverse palmar crease (Simian crease) are additional signs.
Newborns have hypotonia and poor Moro reflex. Higher risk of intellectual disability, congenital heart defects (50%), feeding difficulties, congenital hearing loss, thyroid disease, cataracts, sleep apnea, and early onset of Alzheimer’s disease (average age 54 years).
Down Syndrome
Educate parents about importance of cervical ____ positioning and monitoring for myelopathic signs and symptoms. Contact sports (football, soccer, gymnastics) may place at higher risk of (1) injury. Avoid tr_____ use unless under professional supervision. Special Olympics requires specific screening for some sports.
Educate parents about importance of cervical spine positioning and monitoring for myelopathic signs and symptoms. Contact sports (football, soccer, gymnastics) may place at higher risk of spinal cord injury. Avoid trampoline use unless under professional supervision. Special Olympics requires specific screening for some sports.
Fetal Alcohol Syndrome
Also known as fetal alcohol spectrum disorder.
Classic fetal alcohol syndrome (FAS) f____ is a ____ head (microcephaly) with _____ palpebral fissures (____ eyes) with epic_____ folds and a ____ nasal bridge. There is a th___ upper lip with no vertical groove above the upper lip (smooth ph_____). E___ are underdeveloped.
Can range from neuro______ and be_____ problems (e.g., attention deficit disorder [ADD]) to more severe intellectual disabilities.
Is there any safe time or amount of alcohol during pregnancy?
Alcohol adversely affects the (1) system, somatic gr____, and f____ structure development.
Also known as fetal alcohol spectrum disorder.
Classic fetal alcohol syndrome (FAS) facies is a small head (microcephaly) with shortened palpebral fissures (narrow eyes) with epicanthal folds and a flat nasal bridge. There is a thin upper lip with no vertical groove above the upper lip (smooth philtrum). Ears are underdeveloped.
Can range from neurocognitive and behavioral problems (e.g., attention deficit disorder [ADD]) to more severe intellectual disabilities.
There is no safe dose or time for alcohol during pregnancy.
Alcohol adversely affects the central nervous system (CNS), somatic growth, and facial structure development.
Cryptorchidism (Undescended Testicle)
____ scrotal sac(s). Most cases involve undescended testicles. One or two testicles may be missing. Testis does not descend with m_____ of the inguinal area.
Majority of cases (90%) of cryptorchidism are associated with p____ processus vaginalis. Infant should be sitting, and the exam room should be w____ to relax muscles when massaging the inguinal canal. Another option is to examine child after a warm bath.
Increased risk of testicular _____ if testicles are not removed from the abdomen. Surgical correction (1) necessary within the _____ year of life if testicle does not spontaneously descend.
Empty scrotal sac(s). Most cases involve undescended testicles. One or two testicles may be missing. Testis does not descend with massage of the inguinal area.
Majority of cases (90%) of cryptorchidism are associated with patent processus vaginalis. Infant should be sitting, and the exam room should be warm to relax muscles when massaging the inguinal canal. Another option is to examine child after a warm bath.
Increased risk of testicular cancer if testicles are not removed from the abdomen. Surgical correction (orchiopexy) necessary within the first year of life if testicle does not spontaneously descend.
Gonococcal Ophtalmia Neonatorum
Symptoms usually show within 2 to 5 days after birth.
Infection can _____ spread, causing (1). Do not _____ treatment by waiting for culture results.
Symptoms include in____ (red) conjunctiva with profuse ______ discharge and sw____ eyelids.
Majority of cases of congenital gonorrhea infection are acquired _____ delivery (intrapartum).
Coinfection with ______ is common with gonococcal infection.
Any neonates with acute ____itis presenting within ___ days or less from birth should be tested for chlamydia, gonorrhea, herpes simplex, and bacterial infection.
Symptoms usually show within 2 to 5 days after birth.
Infection can rapidly spread, causing blindness. Do not delay treatment by waiting for culture results.
Symptoms include injected (red) conjunctiva with profuse purulent discharge and swollen eyelids.
Majority of cases of congenital gonorrhea infection are acquired during delivery (intrapartum).
Coinfection with chlamydia is common with gonococcal infection.
Any neonates with acute conjunctivitis presenting within 30 days or less from birth should be tested for chlamydia, gonorrhea, herpes simplex, and bacterial infection.
Gonococcal Ophtalmia Neonatorum
Order ____ stain, gonococcal _____ (Thayer–Martin media) or P___ test for Neisseria gonorrhoeae, herpes simplex culture, and PCR for Chlamydia trachomatis of eye exudate.
Hospitalize and treat with high-dose intravenous or intramuscular Rx(1)
Preferred prophylaxis is with topical 0.5% Rx(1) ointment (1-cm ribbon per eye) immediately after birth.
Test (and treat) m____ and sexual ____ for STDs/sexually transmitted infections (STIs).
Order Gram stain, gonococcal culture (Thayer–Martin media) or polymerase chain reaction (PCR) test for Neisseria gonorrhoeae, herpes simplex culture, and PCR for Chlamydia trachomatis of eye exudate.
Hospitalize and treat with high-dose intravenous or intramuscular cefotaxime.
Preferred prophylaxis is with topical 0.5% erythromycin ointment (1-cm ribbon per eye) immediately after birth.
Test (and treat) mother and sexual partner for STDs/sexually transmitted infections (STIs).
Chlamydial Ophthalmia Neonatorum (Trachoma)
Symptoms will show 4 to __ days after birth.
Eye___ become ed_____ and red with profuse _____ discharge initially that later becomes p_____.
When obtaining a sample, collect not only the exudate but also (1) cells. Rule out concomitant chlamydial pn_____.
Treated with ______ antibiotics such as oral _____ base or erythromycin ethylsuccinate QID × 14 days. Treatment only 80% effective. May need second course. Use only _____ antibiotics.
The prophylaxis used for gonococcal ophthalmia (t_____0.5% erythromycin) will not prevent neonatal chlamydial conjunctivitis or extraocular infections, thus the importance of prenatal sc_____ and treatment.
______ disease. Test (and treat) m____ and sexual _____ for STDs.
Symptoms will show 4 to 10 days after birth.
Eyelids become edematous and red with profuse watery discharge initially that later becomes purulent.
When obtaining a sample, collect not only the exudate but also conjunctival cells. Rule out concomitant chlamydial pneumonia.
Treated with systemic antibiotics such as oral erythromycin base or erythromycin ethylsuccinate QID × 14 days. Treatment only 80% effective. May need second course. Use only systemic antibiotics.
The prophylaxis used for gonococcal ophthalmia (topical 0.5% erythromycin) will not prevent neonatal chlamydial conjunctivitis or extraocular infections, thus the importance of prenatal screening and treatment.
Reportable disease. Test (and treat) mother and sexual partner for STDs.
Chlamydial (1)
In infants with ophthalmia neonatorum, also rule out concomitant chlamydial _____.
Obtain n______ culture for chlamydia. Infant will have frequent c_____ with bibasilar r____, tachypnea, hyperinflation, and diffused inf______ on chest x-ray.
Treated with Rx(1) QID × 2 weeks. Daily follow-up. _____ disease.
Chlamydial Pneumonia
In infants with ophthalmia neonatorum, also rule out concomitant chlamydial pneumonia.
Obtain nasopharyngeal culture for chlamydia. Infant will have frequent cough with bibasilar rales, tachypnea, hyperinflation, and diffused infiltrates on chest x-ray.
Treated with erythromycin QID × 2 weeks. Daily follow-up. Reportable disease.
Sudden Infant Death Syndrome
A sudden infant death in apparently h_____ infants
Higher risk with ___maturity, ____birth weight, maternal sm_____ and/or drug use, and poverty.
Cause hypothesized to be a multifactorial convergence of intrinsically vulnerable infant (g______ predisposition) during a critical development period with exogenous st______.
To decrease risk, position infants on their ____ (supine); use a f____ sleep surface; encourage b_____feeding and routine imm______; room share _____ bedsharing; offer a p_____ for sleep times; and avoid soft objects and _____ bedding in the sleep area, sm____ exposure, and over_____ infant.
A sudden infant death in apparently healthy infants <12 months, which cannot be explained after a thorough case investigation that includes a scene investigation, autopsy, and review of clinical history.
Higher risk with prematurity, low birth weight, maternal smoking and/or drug use, and poverty.
Cause hypothesized to be a multifactorial convergence of intrinsically vulnerable infant (genetic predisposition) during a critical development period with exogenous stressors.
To decrease risk, position infants on their backs (supine); use a firm sleep surface; encourage breastfeeding and routine immunizations; room share without bedsharing; offer a pacifier for sleep times; and avoid soft objects and loose bedding in the sleep area, smoke exposure, and overheating infant.
Excessive Weight Loss (>___%)
Newborns are ex______ to lose weight during the first few days of life. Weight loss can vary by feeding method and delivery type; infants delivered by (1) tend to lose a larger percentage of birth weight than their (1)delivered counterparts. ______-fed infants may lose up to 5%, and _____-fed infants may lose 7% to 10% of their birth weight.
Any loss from birth weight should be regained within 10 to ___ days. Weight loss beyond ___% in neonates is considered abnormal. Assess the infant for de_____, el_____disturbances, and hyperbi______, and the mother and infant for lactation difficulties.
Excessive Weight Loss (>10%)
Newborns are expected to lose weight during the first few days of life. Weight loss can vary by feeding method and delivery type; infants delivered by cesarean section (C-section) tend to lose a larger percentage of birth weight than their vaginally delivered counterparts. Formula-fed infants may lose up to 5%, and breast-fed infants may lose 7% to 10% of their birth weight.
Any loss from birth weight should be regained within 10 to 14 days. Weight loss beyond 10% in neonates is considered abnormal. Assess the infant for dehydration, electrolyte disturbances, and hyperbilirubinemia, and the mother and infant for lactation difficulties.
Dehydration
Signs of severe dehydration (>10% weight loss) in an infant are w___ and r____ pulse, ____pnea or deep breathing, par____ mucous membranes, anterior fontanelle that is markedly s____, skin turgor showing t_____, c____ skin, acrocy____, anuria, and change in LOC (lethargy to coma).
Refer severely dehydrated infants to the ___ for (1) hydration. Severe dehydration due to acute g______ is one of the leading causes of death of infants in the developing world.
Signs of severe dehydration (>10% weight loss) in an infant are weak and rapid pulse, tachypnea or deep breathing, parched mucous membranes, anterior fontanelle that is markedly sunken, skin turgor showing tenting, cool skin, acrocyanosis, anuria, and change in LOC (lethargy to coma).
Refer severely dehydrated infants to the ED for intravenous (IV) hydration. Severe dehydration due to acute gastroenteritis is one of the leading causes of death of infants in the developing world.
(1)
Most common type of pigmented skin lesions in newborns. Present in almost all Asians (85%–100%) and in more than half of Native American, Hispanic, and Black neonates. Blue- to black-colored patches or stains. A common location is the lumbosacral area (but can be located anywhere on the body). May be mistaken for bruising or child abuse. Usually fade by age 2 to 3 years.
Congenital Dermal Melanocytosis (Mongolian Spots)
(1)
Most common in neonates. Multiple white 1- to 2-mm papules located mainly on the forehead, cheeks, and nose. Due to retention of sebaceous material and keratin. Resolves spontaneously.
Milia, Miliaria, or “Prickly Heat”
(1)
Small pustules (whitish-yellow color) that are 1- to 3-mm in size and surrounded by a red base. Erupt during the second to the third day of life. Located on the face, chest, back, and extremities. Last from 1 to 2 weeks and resolve spontaneously.
Erythema Toxicum Neonatorum
(1)
Excessive thick scaling on the scalp of younger infants. Treated by softening and removal of the thick scales on the scalp after soaking scalp a few hours (to overnight) with vegetable oil or mineral oil. Shampoo scalp and gently scrub scales with soft comb. Prevention is by frequent shampooing with mild baby shampoo and removing scales with soft brush or comb. Self-limited condition that resolves spontaneously within a few months.
Seborrheic Dermatitis (“Cradle Cap”)
(1)
Tufts of hair overlying spinal column usually at lumbosacral area. May be a sign of neural tube defects (spina bifida, spina bifida occulta). Perform neurologic exam focusing on lumbosacral nerves (fecal/urinary in______, problems with g___). Order (1) of lesion to rule out (1).
Faun Tail Nevus
Tufts of hair overlying spinal column usually at lumbosacral area. May be a sign of neural tube defects (spina bifida, spina bifida occulta). Perform neurologic exam focusing on lumbosacral nerves (fecal/urinary incontinence, problems with gait). Order ultrasound of lesion to rule out occult spina bifida.
(1)
Flat light-brown to dark-brown spots >___ mm (0.5 cm). If ___ or more spots larger than 5 mm (0.5 cm) in diameter are seen, rule out neuro_______or von R_______ disease (e.g., neurologic disorder marked by seizures, learning disorders). Refer to pediatric (1) if the spots meet the same criteria to rule out neurofibromatosis.
Café Au Lait Spots
Flat light-brown to dark-brown spots >5 mm (0.5 cm). If six or more spots larger than 5 mm (0.5 cm) in diameter are seen, rule out neurofibromatosis or von Recklinghausen’s disease (e.g., neurologic disorder marked by seizures, learning disorders). Refer to pediatric neurologist if the spots meet the same criteria to rule out neurofibromatosis.
(1)
A vascular lesion often referred to as “____ bites” or “____ kisses.” Flat pink patches found on the forehead, eyelids, and nape of neck (Figure 1). Usually appear on both sides of the ____line (i.e., on both eyelids or across the entire nape of neck). ____chable, but color changes with crying, breath holding, and room temperature changes. Consider Beckwith–Wiedemann or FAS if glabellar lesion seen. Typically f____ by 18 months.
Salmon Patches (Nevus Simplex)
A vascular lesion often referred to as “stork bites” or “angel kisses.” Flat pink patches found on the forehead, eyelids, and nape of neck (Figure 1). Usually appear on both sides of the midline (i.e., on both eyelids or across the entire nape of neck). Blanchable, but color changes with crying, breath holding, and room temperature changes. Consider Beckwith–Wiedemann or FAS if glabellar lesion seen. Typically fade by 18 months.
(1)
Neonates with pink-to-red, flat, stain-like skin lesions located on the upper and lower eyelids or on the V1 and V2 branches of the _______ nerve (CN V) should be referred to a pediatric ophthalmologist to rule out congenital (1). Blanches to pressure. Irregular in size and shape. Usually unilateral. Large lesions located on half the facial area may be a sign of trigeminal nerve involvement and Sturge–Weber syndrome (rare neurologic disorder). The lesions do _____ regress and grow with the child. These lesions can be treated with (1) (PDL) therapy.
Port Wine Stain (Nevus Flammeus)
Neonates with pink-to-red, flat, stain-like skin lesions located on the upper and lower eyelids or on the V1 and V2 branches of the trigeminal nerve (CN V) should be referred to a pediatric ophthalmologist to rule out congenital glaucoma. Blanches to pressure. Irregular in size and shape. Usually unilateral. Large lesions located on half the facial area may be a sign of trigeminal nerve involvement and Sturge–Weber syndrome (rare neurologic disorder). The lesions do not regress and grow with the child. These lesions can be treated with pulse-dye laser (PDL) therapy.
(1)
Raised vascular lesions ranging in size from 0.5 to 4.0 cm that are bright red in color and feel soft to palpation. Usually located on the head or the neck. The lesions often grow rapidly during the first 12 months of life, but the majority will involute gradually over the next 1 to 5 years. Watchful waiting is the usual strategy. Can be treated with (1) therapy.
Hemangioma (Strawberry Hemangioma)
Raised vascular lesions ranging in size from 0.5 to 4.0 cm that are bright red in color and feel soft to palpation. Usually located on the head or the neck. The lesions often grow rapidly during the first 12 months of life, but the majority will involute gradually over the next 1 to 5 years. Watchful waiting is the usual strategy. Can be treated with PDL therapy.
Vision Screening
Newborn Vision
Newborns are ____-sighted (myopia) and have a vision of 20/400.
They can focus best at a distance of 8 to ___ inches.
During the first 2 months, the infant’s eyes may appear cr_____ (or wander) at times (normal finding). If one eye is consistently turned in or turned out, refer to pediatric ophthalmologist.
Human f____ is preferred by newborns.
Newborns do ___ shed ____ , because the lacrimal ducts are not fully mature at birth.
Caucasian neonates are born with blue-gray eyes. It is normal for their eye color to _____ as they mature.
R_____ (CN II) are immature at birth and reach maturity at age 6 years.
Newborns are nearsighted (myopia) and have a vision of 20/400.
They can focus best at a distance of 8 to 10 inches.
During the first 2 months, the infant’s eyes may appear crossed (or wander) at times (normal finding). If one eye is consistently turned in or turned out, refer to pediatric ophthalmologist.
Human face is preferred by newborns.
Newborns do not shed tears, because the lacrimal ducts are not fully mature at birth.
Caucasian neonates are born with blue-gray eyes. It is normal for their eye color to change as they mature.
Retinas (CN II) are immature at birth and reach maturity at age 6 years.
Infant Screening
Match these descriptions with what an infant’s vision at 1, 3, 6, and 12 months
- (1)**:* Makes good eye contact. Turns head to scan surroundings with 180-degree visual field.
- (1)**:* Infant will hold the hands close to the face to observe them. Hold a bright object or a toy in front of the infant. Watch behavior as the infant fixates and follows the toy for a few seconds. Avoid using objects/toys that make noises when testing vision.
- (1):* Makes prolonged eye contact when spoken to. Will actively turn head around 180 degrees to observe people and surroundings for long periods. Recognizes self in a mirror and parents and favorite people from a longer distance.
- (1)**:* Infant can fixate briefly on the mother’s face. Prefers the human face.
- 6 months:* Makes good eye contact. Turns head to scan surroundings with 180-degree visual field.
- 3 months**:* Infant will hold the hands close to the face to observe them. Hold a bright object or a toy in front of the infant. Watch behavior as the infant fixates and follows the toy for a few seconds. Avoid using objects/toys that make noises when testing vision.
- 12 months:* Makes prolonged eye contact when spoken to. Will actively turn head around 180 degrees to observe people and surroundings for long periods. Recognizes self in a mirror and parents and favorite people from a longer distance.
- 1 month:* Infant can fixate briefly on the mother’s face. Prefers the human face.
Abnormal Vision Findings in Newborns
(1): Misalignment of the eye.
(1): Reduced vision in one eye caused by abnormal visual development early in life. The weaker — or lazy — eye often wanders inward or outward- If corrected early, affected eye can have normal vision
(1): Misalignment of one or both eyes (“cross-eyed”)
- Strabismus*: Misalignment of the eye.
- Amblyopia (“Lazy Eye”):*Reduced vision in one eye caused by abnormal visual development early in life**. The weaker — or lazy — eye often wanders inward or outward
- Esotropia*: Misalignment of one or both eyes (“cross-eyed”)
Strabismus
Mis______ of the eye.
Horizontal strabismus may be ___tropia (inward turning of the eyes) or ____tropia (outward turning of the eyes).
Vertical strabismus may be h____tropia (one eye higher than the other) or h____tropia (one eye lower than the other).
Uncorrected strabismus can result in permanent visual ____ and abnormal vision such as _____ (double vision).
Treatment can range from eyegl____, eye ex____, prism, and/or eye muscle s_____.
Misalignment of the eye.
Horizontal strabismus may be esotropia (inward turning of the eyes) or exotropia (outward turning of the eyes).
Vertical strabismus may be hypertropia (one eye higher than the other) or hypotropia (one eye lower than the other).
Uncorrected strabismus can result in permanent visual loss and abnormal vision such as diplopia (double vision).
Treatment can range from eyeglasses, eye exercises, prism, and/or eye muscle surgery.
Esotropia
Misalignment of one or both eyes (“____-eyed”).
Infants (<20 weeks) may have intermittent esotropia, which usually resolves sp______.
Some infants with obvious epicanthal folds appear “cross-eyed” (_____strabismus), but corneal light reflex will be normal. Refer to pediatric ophthalmologist if in doubt.
Misalignment of one or both eyes (“cross-eyed”).
Infants (<20 weeks) may have intermittent esotropia, which usually resolves spontaneously.
Some infants with obvious epicanthal folds appear “cross-eyed” (pseudostrabismus), but corneal light reflex will be normal. Refer to pediatric ophthalmologist if in doubt.
Indications for Referral
Abnormal ___ reflex (rule out retinoblastoma, cataract, glaucoma)
Presence of _____ reflex (rule out retinoblastoma)
Str______ (rule out CN III, IV, and VI abnormalities, retinoblastoma)
Greater than ____-line difference between each eye
Esodeviation present after 3 to ___ months of age
Corneal ____ reflex test with abnormal result
Sh_____/appearance of pupils not equal
New onset of st_______ (e.g., retinoblastoma, brain mass, bleeding, lead poisoning)
Abnormal red reflex (rule out retinoblastoma, cataract, glaucoma)
Presence of white reflex (rule out retinoblastoma)
Strabismus (rule out CN III, IV, and VI abnormalities, retinoblastoma)
Greater than two-line difference between each eye
Esodeviation present after 3 to 4 months of age
Corneal light reflex test with abnormal result
Shape/appearance of pupils not equal
New onset of strabismus (e.g., retinoblastoma, brain mass, bleeding, lead poisoning)
Red Reflex
Screening test for (2)
How to perform red reflex test?
Abnormal if there are white-colored opacities (1) or white spots (1).
Determine presence of white reflex, rule out (1), and refer infant to (1) as soon as possible.
Even if the test is normal during the visit, but a parent reports that one eye appears white on a digital ph_______, refer.
If absence or decreased intensity of red reflex, rule out (1) and refer to pediatric ophthalmologist.
Screening test for Cataracts and Retinoblastoma.
Procedure: Perform test in a darkened room. Use a direct ophthalmoscope and shine light about 12 to 18 inches away from the infant. Normal finding is symmetrical and round orange-red glow from each eye.
Abnormal if there are white-colored opacities (cataracts) or white spots (leukocoria).
Determine presence of white reflex, rule out retinoblastoma, and refer infant to pediatric ophthalmologist as soon as possible.
Even if the test is normal during the visit, but a parent reports that one eye appears white on a digital photograph, refer.
If absence or decreased intensity of red reflex, rule out cataract and refer to pediatric ophthalmologist.
Red reflex exam on neonate shows a round, white-colored pupil.
Congenital Cataracts
(1)
Screening test for strabismus. Abnormal if corneal light reflex is not clear or if it is “off-center.”
Procedure =
Light Reflex Test or Corneal Light Reflex (Hirschberg Test)
Procedure: Shine light directly in eyes (24 inches away) using a fixation target. Infant or child must look directly forward with both eyes aligned. Observe for the symmetry and brightness of light reflecting from both eyes.
Hearing Screening
Universal screening for hearing loss is done when?
Newborns
Each ____ has its own rules about neonatal hearing exams.
Universal screening for hearing loss is done while in nursery before discharge.
Newborns
Each state has its own rules about neonatal hearing exams.
Auditory Brainstem Response
Measures the CN ____ by the use of “____” stimuli.
- Procedure:*
- Otoacoustic Emissions*
- Gross hearing test*: As a response to ____ noise, look for st_____ response (neonates), bl____, t_____ toward sound.
Measures the _____ ear mobility only. ____ sensitive than the auditory brainstem response (ABR).
Auditory Brainstem Response
Measures the CN VIII by the use of “click” stimuli.
- Procedure:* An audiologist places small earphones in the child’s ears and soft electrodes (small sensor stickers) near the ears and on the forehead. Clicking sounds and tones go through the earphones, and electrodes measure how the hearing nerves and brain respond to the sounds.
- Otoacoustic Emissions*
- Gross hearing test*: As a response to loud noise, look for startle response (neonates), blinking, turning toward sound.
Measures the middle ear mobility only. Less sensitive than the auditory brainstem response (ABR).
- High-Risk Factors for Hearing Loss Mnemonic*
- (1)*
Premature infants and infants admitted to NICUs have a ____ incidence of hearing loss compared with full-term infants.
HEARS
H (hyperbilirubinemia)
E (ear infections that are frequent)
A (Apgar scores low at birth)
R (rubella, cytomegalovirus [CMV], toxoplasmosis infections)
S (seizures)
Premature infants and infants admitted to NICUs have a higher incidence of hearing loss compared with full-term infants.
Hearing Screening Laboratory Tests
Testing varies from state to state. Blood is obtained by h____ stick or from c____ blood. A spot of blood is blotted into filter paper for stable transport.
- _____-Stimulating Hormone
- Phenyl______ (PKU)
- _____ Cell Disease
- H_____ and H______
- L_____ Screening
Testing varies from state to state. Blood is obtained by heel stick or from cord blood. A spot of blood is blotted into filter paper for stable transport.
- Thyroid-Stimulating Hormone
- Phenylketonuria
- Sickle Cell Disease
- Hemoglobin and Hematocrit
- Lead Screening
Thyroid-Stimulating Hormone
(Hearing Loss Screening)
Thyroid-stimulating hormone (TSH) testing is f_____ mandated. Lack of thyroid hormone results in mental and somatic g____ retardation. Treated by thyroid hormone s_______.
Thyroid-stimulating hormone (TSH) testing is federally mandated. Lack of thyroid hormone results in mental and somatic growth retardation. Treated by thyroid hormone supplementation.
Phenylketonuria (PKU)
(Hearing Loss Screening)
Phenylketonuria (PKU) testing is f_____ mandated. Severe int______ disability results if not treated early.
Disorder is an inability to m______ (1) to (1) because of a defect in the production of the en______ phenylalanine hydroxylase.
Perform test only after infant has pr______ feeding (breast milk or formula) for at least ___ hours. Higher risk of false negatives if done too e____ (<48 hours). Treated by following special diet (_____ free diet)
Phenylketonuria (PKU) testing is federally mandated. Severe intellectual disability results if not treated early.
Disorder is an inability to metabolize phenylalanine to tyrosine because of a defect in the production of the enzyme phenylalanine hydroxylase.
Perform test only after infant has protein feeding (breast milk or formula) for at least 48 hours. Higher risk of false negatives if done too early (<48 hours). Treated by following special diet (phenylalanine-free diet).
Sickle Cell Disease
The required test can detect four types of hemoglobin (4).
Lead Screening
High-risk children (e.g., children living below p_____ level or living in homes built prior to 19__) should be screened at (2) ages
Sickle Cell Disease
The required test can detect four types of hemoglobin (F, S, A, and C).
Lead Screening
High-risk children (e.g., children living below poverty level or living in homes built prior to 1978) should be screened at age 1 and 2 years (12 and 24 months).
Hemoglobin and Hematocrit
(Hearing Loss Screening)
Normal newborns have (2) types of hemoglobin
Healthy term infants have enough ____ stores to last up to __ months.
Screening for anemia is done in late infancy (__-__ months) for healthy full-term infants.
Why do we not screen for anemia/hemoglobin at birth?
Normal newborns have hemoglobin F (fetal hemoglobin) and hemoglobin A.
Healthy term infants have enough iron stores to last up to 6 months.
Screening for anemia is done in late infancy (9–12 months) for healthy full-term infants.
Not screened at birth, because hemoglobin is elevated from maternal red blood cells (RBCs) mixed in fetal RBCs.
Nutritional Intake
Breastfeeding vs. Formula?
If formula, start with one that is?
Breastfeeding > Formula.
If formula chosen, start with one fortified with iron.
Breastfeeding
What do you have to supplement with if breastfeeding? Why?
- Breast milk or formula contains ___ calories per ounce.
- Decreases risk of _____ (e.g., ____ media) during the first few weeks of life.
Give vitamin D drops (400 IU of vitamin D) starting in the first few days of life if breastfeeding because breast milk alone does not provide adequate levels of vitamin D. Infant formula is supplemented with vitamin D, iron, other vitamins, and essential fatty acids.
Breast milk or formula contains 20 calories per ounce.
Decreases risk of infections (e.g., otitis media) during the first few weeks of life.
(1)
Sticky and thick, yellowish fluid that comes before breast milk. Secreted first few days after the birth and contains large amounts of maternal (1) and nutrients.
Colostrum
Sticky and thick, yellowish fluid that comes before breast milk. Secreted first few days after the birth and contains large amounts of maternal antibodies and nutrients.
Cow’s Milk in first year of life?
Avoid cow’s milk the first year of life (causes gastrointestinal [GI] bleeding)
Common cause of iron-deficiency anemia in babies and young children
Solid Foods
When to start?
What food should you start with? Frequency and before or after breast milk/formula?
Why should you avoid feeding only rice cereal?
Introduce one food at a time for 4-5 days why?
Recommended to wait until 4 to 6 months for complementary foods.
Start with a single-grain, iron-fortified baby cereal, mix with four tablespoons of breast milk/formula. Serve once or twice a day after bottle or breastfeeding.
Avoid feeding only rice cereal due to possible exposure to arsenic.
Introduce one food at a time for 4 to 5 days (if allergic, easier to identify offending food).
(1)
Thick dark-green to black-colored stool that is odorless. Most full-term neonates pass this stool within a few hours of birth.
Failure to pass this stool within 24 hours of birth is worrisome and may be a sign of intestinal _____ , Hir_____ disease, or c____ f_____.
Meconium
Failure to pass this stool within 24 hours of birth is worrisome and may be a sign of intestinal obstruction, Hirschsprung’s disease, or cystic fibrosis.
Head Findings
Caput _______ is diffused edema of the scalp that crosses the midline.
Caused by intrauterine and vaginal pr____ from prolonged or difficult vaginal labor.
The scalp becomes molded and “____ -shaped.”
____-limited and resolves ________.
Caput succedaneum is diffused edema of the scalp that crosses the midline.
Caused by intrauterine and vaginal pressure from prolonged or difficult vaginal labor.
The scalp becomes molded and “cone shaped.”
Self-limited and resolves spontaneously.
Head Circumference
Also known as the occipitofrontal circumference (OFC). Use paper tape (cloth tape stretches) and place ____ the ear.
Average head circumference at birth is ___ cm
Head circumference is measured at each wellness visit until the age of ___ years
In newborns, chest size relative the head circumference?
Head circumference will increase by __ cm during the first 12 months.
Fastest rate of head growth is during the first ___ months of life (2 cm per month)
Also known as the occipitofrontal circumference (OFC). Use paper tape (cloth tape stretches) and place above the ear.
Average head circumference at birth is 13.7 inches (35 cm).
Head circumference is measured at each wellness visit until the age of 36 months (3 years).
In newborns, chest is about 1 to 2 cm smaller in size than the head circumference.
Head circumference will increase by 12 cm during the first 12 months.
Fastest rate of head growth is during the first 3 months of life (2 cm per month)
(1)
Traumatic subperiosteal hemorrhage. Rule out skull fracture (order radiographs of the skull). Swelling does not cross the midline or suture lines.
Cephalohematoma
A cephalohematoma is an accumulation of blood under the scalp. During the birth process, small blood vessels on the head of the fetus are broken as a result of minor trauma
Birth Weight
What happens to the weight of neonates in the first 2 weeks?
What is their weight by 6 months, by 12 months?
Neonates lose up to 10% of body weight but should regain it by 2 weeks of age.
They double their birth weight by 6 months and triple their birth weight by 12 months.
Infant Weight and Length Gain
- 0 to 6 months:* (1) ounces per week and (1) inch per month
- 6 to 12 months:* (1) ounces per week and (1) inch per month
- 0 to 6 months:* 6 to 8 ounces per week and 1 inch per month
- 6 to 12 months:* 3 to 4 ounces per week and 1/2 inch per month
Infant Weight and Length Gain
If the child’s weight and/or length decelerates across ____ or more major percentiles, rule out (1) (see “Danger Signals”).
In addition, any child who is at the ____ to ___ percentile is considered to have FTT.
Of the many causes of FTT, the most common in primary care are under or mal_______. Evaluate the child, but do not forget to assess maternal b____ and dep______
If the child’s weight and/or length decelerates across two or more major percentiles, rule out FTT (see “Danger Signals”).
In addition, any child who is at the third to fifth percentile is considered to have FTT.
Of the many causes of FTT, the most common in primary care are undernutrition and malnutrition. Evaluate the child, but do not forget to assess maternal bonding and depression.
Length and Height
Till what age do you measure a child’s LENGTH (linear growth)?
At what age should you start measuring a child’s HEIGHT (standing up)?
Plot the measurements on the infant’s or child’s percentile ___ chart.
Length (linear growth) of infants is measured from birth to about 24 months.
Starting at the age of 2 years, measure height (child is standing up) and calculate body mass index (BMI).
Plot the measurements on the infant’s or child’s percentile growth chart.
Dentition
Both the left and right teeth erupt bilaterally at the same time (symmetrical). Symptoms are dr____, ch_____ on objects, irr______, crying, and low-grade _____.
- 6 to __ months of age: (1) set of teeth that erupt first
- ____ years of age: Has complete set of primary teeth (20 teeth)
- Typically lose teeth in ____ order that they erupted
Both the left and right teeth erupt bilaterally at the same time (symmetrical). Symptoms are drooling, chewing on objects, irritability, crying, and low-grade fever.
- 6 to 10 months of age: Lower central incisors (lower front teeth)
- 2½ years of age: Has complete set of primary teeth (20 teeth)
- Typically lose teeth in same order that they erupted
First Permanent Teeth (Deciduous Teeth)
When do they get their first permanent teeth?
First permanent teeth to erupt are upper and lower (1)
6 years of age
Shed central incisors, first permanent teeth to erupt are upper and lower first molars
Genitourinary Anomalies
- (1)**:* Urethral meatus located on the ventral aspect (underside) of the penis. Location may be at the glans or shaft. Some have two urethral openings; one opening is normal, and the other opening is lower on the glans or shaft. Refer to pediatric urologist.
- (1)**:* Urethral meatus is located on the dorsal aspect (upper side) of the penis.
- Hypospadias**:* Urethral meatus located on the ventral aspect of the penis. Location may be at the glans or shaft. Some have two urethral openings; one opening is normal, and the other opening is lower on the glans or shaft. Refer to pediatric urologist.
- Epispadias**:* Urethral meatus is located on the dorsal aspect (upper side) of the penis.
Genitourinary Anomalies
- (1):* Presence of fluid inside the scrotum (tunica vaginalis/processus vaginalis) that results in swelling of the affected scrotum. Skin is normal color and temperature. Fairly common in newborn males. Incidence rate is 10 to 20 cases out of every 1,000 live births.
- (1):* Affected testicle(s) will show increased size in the “glow” of light compared with the normal scrotum. Darken the room and place the light source on the scrotal skin. Compare each scrotum.
- Hydrocele**:* Presence of fluid inside the scrotum (tunica vaginalis/processus vaginalis) that results in swelling of the affected scrotum. Skin is normal color and temperature. Fairly common in newborn males. Incidence rate is 10 to 20 cases out of every 1,000 live births.
- Transillumination**:* Affected testicle(s) will show increased size in the “glow” of light compared with the normal scrotum. Darken the room and place the light source on the scrotal skin. Compare each scrotum.
Genitourinary Anomalies
- (1)**:* Newborn female vagina- Caused by withdrawal of maternal hormones and will disappear within a few days.
- (1)*: Retention of one or both testicles in the abdominal cavity or the inguinal canal. Markedly increases risk of testicular ____ and in_____. Order inguinal and abdominal ______. Corrected s_____ before __ months of age.
- Newborn female vagina swollen with small amount of blood-tinged discharge**:* Caused by withdrawal of maternal hormones and will disappear within a few days.
- Cryptorchidism*: Retention of one or both testicles in the abdominal cavity or the inguinal canal. Markedly increases risk of testicular cancer and infertility. Order inguinal and abdominal ultrasound. Corrected surgically before 12 months of age.
Exam Tips
Weight loss of (1)-(1)% starts after birth, but neonates should regain birth weight in __ weeks.
Birth weight _____ at 6 months and _____ at 12 months.
Head circumference grows by up to ___ cm (first 12 months).
Caput succedaneum vs. Cephalohematoma presentation?
Weight loss of 7% to 10% starts after birth, but neonates should regain birth weight in 2 weeks.
Birth weight doubles at 6 months and triples at 12 months.
Head circumference grows by up to 12 cm (first 12 months).
Caput succedaneum crosses midline, and cephalohematoma does not (blood blocked by scalp sutures).
Exam Tips
(1) (IgG ______) looks like thick, yellowish fluid and is secreted the first few days of breastfeeding before milk release.
Avoid cow’s milk during first 12 months of life (causes (2))
- Breastfeeding:* Supplement with (1) the first few days of life.
- (1):* White papules found on gum line resembles an erupting tooth.
Do not confuse questions asking for the “first tooth” (when and which?) with the “first permanent tooth. (when and which?)
Colostrum (IgG antibodies) looks like thick, yellowish fluid and is secreted the first few days of breastfeeding before milk release.
Avoid cow’s milk during first 12 months of life (causes GI bleeding, iron-deficiency anemia).
- Breastfeeding:* Supplement with vitamin D the first few days of life.
- Epstein’s pearls:* White papules found on gum line resembles an erupting tooth.
Do not confuse questions asking for the “first tooth” (6-10m, lower central incisors) with the “first permanent tooth.” (6 years, first upper and lower molars)
Exam Tips
- (1):* Urethral opening under glans/shaft (refer to (1)).
- (1):* Urethral opening on top of glans/shaft (refer to (1)).
Cryptorchidism increases risk of (1). Refer to (1) for evaluation between __ and __ months of age.
- Hypospadias:* Urethral opening under glans/shaft (refer to pediatric urologist).
- Epispadias:* Urethral opening on top of glans/shaft (refer to pediatric urologist).
Cryptorchidism increases risk of testicular cancer. Refer to pediatric urologist for evaluation between 6 and 12 months of age.
Exam Tips
(1) is used to assess for hydrocele, empty scrotal sac, and scrotal masses.
(1) is fluid collection inside the scrotum (tunica vaginalis/processus vaginalis).
* Infant with hydrocele and transillumination:* Scrotal sac with hydrocele will appear “br_____” or will have more light gl___ compared with scrotum with a testicle (solid objects block light, so less glow of light).
Transillumination is used to assess for hydrocele, empty scrotal sac, and scrotal masses.
Hydrocele is fluid collection inside the scrotum (tunica vaginalis/processus vaginalis).
Infant with hydrocele and transillumination: Scrotal sac with hydrocele will appear “brighter” or will have more light glow compared with scrotum with a testicle (solid objects block light, so less glow of light).
Anal Wink Reflex
How to perform?
Expected result?
Abnormal result and what it means?
Gently stroke the anal region.
Look for contraction of the perianal muscle.
Absence is abnormal and suggestive of a lesion on the spinal cord (e.g., spina bifida).
Plantar Reflex (Babinski Reflex)
How to perform?
Normal reflex up to how long?
Upward extension of the big toe with fanning of the other toes. Starting on the heel, stroke firmly the outer side of the sole toward the front of the foot (Figure 1).
Should dissappear by 1-2 years
Palmar Reflex (Grasp Reflex)
=
Place a finger on the infant’s open palm. The infant closes its hand around the finger. Pulling away the examiner’s finger causes the infant’s grip to tighten.
Moro Reflex (Startle Reflex)
How to perform?
When should this reflex disappear?
- Absence on ___ side*: Rule out brachial plexus injury, fracture, or shoulder dystocia.
- Absence on ____ sides*: Rule out spinal cord or brain lesion.
- Older infant*: Per_____ of Moro reflex is abnormal. Rule out br___pathology.
Sudden loud noise will cause symmetric abduction and extension of the arms followed by adduction and flexion of the arms over the body.
Disappears by 3 to 4 months.
- Absence on one side*: Rule out brachial plexus injury, fracture, or shoulder dystocia.
- Absence on both sides*: Rule out spinal cord or brain lesion.
- Older infant*: Persistence of Moro reflex is abnormal. Rule out brain pathology.
Step Reflex
How to perform?
Absent with par____ and br____ births.
Should disappear by?
Hold baby upright and allow the dorsal surface of one foot to touch the edge of a table. Baby will flex the hip and knee and place the stimulated foot on the tabletop (stepping motion).
Absent with paresis and breech births.
Disappears by 6 weeks.
Blink Reflex
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Eyelids will close in response to bright light or touch.
Tonic Neck Reflex (Fencing Reflex)
=
Turning head to one side with jaw over shoulder causes the arm and leg on the same side to extend. The arm and leg on the opposite side will flex.
Rooting Reflex
=
Should disappear by?
Stroking the corner of the mouth causes baby to turn toward stimulus and suck.
Disappears by 3 to 4 months.