Peds: Newborns-Toddlers Flashcards
Danger Signals
Failure to _____
D___ Syndrome
Fetal _____ Syndrome
(1) (Undescended Testicle)
G______ Ophtalmia Neonatorum
Ch_____ Ophthalmia Neonatorum (Trachoma)
Chlamydial Pn______
Sudden Infant ______ Syndrome
Excessive Weight Loss (>___%)
De______
Failure to Thrive
Down Syndrome
Fetal Alcohol Syndrome
Cryptorchidism (Undescended Testicle)
Gonococcal Ophtalmia Neonatorum
Chlamydial Ophthalmia Neonatorum (Trachoma)
Chlamydial Pneumonia
Sudden Infant Death Syndrome
Excessive Weight Loss (>10%)
Dehydration
Failure to Thrive
Defined as weight for age that falls below __-__ percentile for gestation-corrected age and gender when plotted on appropriate growth chart (on more than one occasion).
Also, infants whose rate of weight change decreases over ____ or more major percentile lines (90th, 75th, 50th, 25th, and 5th) exhibit failure to thrive (FTT; e.g., a child at the 50th percentile goes down to 5th percentile over a few months).
Use (1) charts until the age of 2 years, and then (1) growth charts.
In most cases seen in primary care, causes are usually inadequate di____ intake, dia____, mal______ (celiac disease, cystic fibrosis, food allergy), poor maternal b_____, frequent in_____, and others.
Defined as weight for age that falls below 3rd to 5th percentile for gestation-corrected age and gender when plotted on appropriate growth chart (on more than one occasion).
Also, infants whose rate of weight change decreases over two or more major percentile lines (90th, 75th, 50th, 25th, and 5th) exhibit failure to thrive (FTT; e.g., a child at the 50th percentile goes down to 5th percentile over a few months).
Use World Health Organization (WHO) growth charts until the age of 2 years, and then Centers for Disease Control and Prevention (CDC) growth charts.
In most cases seen in primary care, causes are usually inadequate dietary intake, diarrhea, malabsorption (celiac disease, cystic fibrosis, food allergy), poor maternal bonding, frequent infections, and others.
Down Syndrome
A genetic defect caused by tr____ of chromosome ___ (three copies instead of two). The most common chromosomal disorder; the average life span is ___ years in the United States.
Affected persons have a round face that appears “___” (decreased anterior–posterior diameter), accompanied by __ward-slanting eyes (palpebral fissures) and ___-set ears.
Chronic open mouth caused by enlarged ______ (macroglossia), accompanied by a ______ neck. ____ fingers, ____ palms, and a broad hand with transverse palmar crease (S____ crease) are additional signs.
Newborns have h____tonia and poor M____ reflex. Higher risk of int______ disability, congenital ____ defects (50%), feeding difficulties, congenital h______ loss, th____ disease, cataracts, sleep apnea, and early onset of A______ disease (average age 54 years).
A genetic defect caused by trisomy of chromosome 21 (three copies instead of two). The most common chromosomal disorder; the average life span is 60 years in the United States.
Affected persons have a round face that appears “flat” (decreased anterior–posterior diameter), accompanied by upward-slanting eyes (palpebral fissures) and low-set ears.
Chronic open mouth caused by enlarged tongue (macroglossia), accompanied by a shorter neck. Short fingers, small palms, and a broad hand with transverse palmar crease (Simian crease) are additional signs.
Newborns have hypotonia and poor Moro reflex. Higher risk of intellectual disability, congenital heart defects (50%), feeding difficulties, congenital hearing loss, thyroid disease, cataracts, sleep apnea, and early onset of Alzheimer’s disease (average age 54 years).
Down Syndrome
Educate parents about importance of cervical ____ positioning and monitoring for myelopathic signs and symptoms. Contact sports (football, soccer, gymnastics) may place at higher risk of (1) injury. Avoid tr_____ use unless under professional supervision. Special Olympics requires specific screening for some sports.
Educate parents about importance of cervical spine positioning and monitoring for myelopathic signs and symptoms. Contact sports (football, soccer, gymnastics) may place at higher risk of spinal cord injury. Avoid trampoline use unless under professional supervision. Special Olympics requires specific screening for some sports.
Fetal Alcohol Syndrome
Also known as fetal alcohol spectrum disorder.
Classic fetal alcohol syndrome (FAS) f____ is a ____ head (microcephaly) with _____ palpebral fissures (____ eyes) with epic_____ folds and a ____ nasal bridge. There is a th___ upper lip with no vertical groove above the upper lip (smooth ph_____). E___ are underdeveloped.
Can range from neuro______ and be_____ problems (e.g., attention deficit disorder [ADD]) to more severe intellectual disabilities.
Is there any safe time or amount of alcohol during pregnancy?
Alcohol adversely affects the (1) system, somatic gr____, and f____ structure development.
Also known as fetal alcohol spectrum disorder.
Classic fetal alcohol syndrome (FAS) facies is a small head (microcephaly) with shortened palpebral fissures (narrow eyes) with epicanthal folds and a flat nasal bridge. There is a thin upper lip with no vertical groove above the upper lip (smooth philtrum). Ears are underdeveloped.
Can range from neurocognitive and behavioral problems (e.g., attention deficit disorder [ADD]) to more severe intellectual disabilities.
There is no safe dose or time for alcohol during pregnancy.
Alcohol adversely affects the central nervous system (CNS), somatic growth, and facial structure development.
Cryptorchidism (Undescended Testicle)
____ scrotal sac(s). Most cases involve undescended testicles. One or two testicles may be missing. Testis does not descend with m_____ of the inguinal area.
Majority of cases (90%) of cryptorchidism are associated with p____ processus vaginalis. Infant should be sitting, and the exam room should be w____ to relax muscles when massaging the inguinal canal. Another option is to examine child after a warm bath.
Increased risk of testicular _____ if testicles are not removed from the abdomen. Surgical correction (1) necessary within the _____ year of life if testicle does not spontaneously descend.
Empty scrotal sac(s). Most cases involve undescended testicles. One or two testicles may be missing. Testis does not descend with massage of the inguinal area.
Majority of cases (90%) of cryptorchidism are associated with patent processus vaginalis. Infant should be sitting, and the exam room should be warm to relax muscles when massaging the inguinal canal. Another option is to examine child after a warm bath.
Increased risk of testicular cancer if testicles are not removed from the abdomen. Surgical correction (orchiopexy) necessary within the first year of life if testicle does not spontaneously descend.
Gonococcal Ophtalmia Neonatorum
Symptoms usually show within 2 to 5 days after birth.
Infection can _____ spread, causing (1). Do not _____ treatment by waiting for culture results.
Symptoms include in____ (red) conjunctiva with profuse ______ discharge and sw____ eyelids.
Majority of cases of congenital gonorrhea infection are acquired _____ delivery (intrapartum).
Coinfection with ______ is common with gonococcal infection.
Any neonates with acute ____itis presenting within ___ days or less from birth should be tested for chlamydia, gonorrhea, herpes simplex, and bacterial infection.
Symptoms usually show within 2 to 5 days after birth.
Infection can rapidly spread, causing blindness. Do not delay treatment by waiting for culture results.
Symptoms include injected (red) conjunctiva with profuse purulent discharge and swollen eyelids.
Majority of cases of congenital gonorrhea infection are acquired during delivery (intrapartum).
Coinfection with chlamydia is common with gonococcal infection.
Any neonates with acute conjunctivitis presenting within 30 days or less from birth should be tested for chlamydia, gonorrhea, herpes simplex, and bacterial infection.
Gonococcal Ophtalmia Neonatorum
Order ____ stain, gonococcal _____ (Thayer–Martin media) or P___ test for Neisseria gonorrhoeae, herpes simplex culture, and PCR for Chlamydia trachomatis of eye exudate.
Hospitalize and treat with high-dose intravenous or intramuscular Rx(1)
Preferred prophylaxis is with topical 0.5% Rx(1) ointment (1-cm ribbon per eye) immediately after birth.
Test (and treat) m____ and sexual ____ for STDs/sexually transmitted infections (STIs).
Order Gram stain, gonococcal culture (Thayer–Martin media) or polymerase chain reaction (PCR) test for Neisseria gonorrhoeae, herpes simplex culture, and PCR for Chlamydia trachomatis of eye exudate.
Hospitalize and treat with high-dose intravenous or intramuscular cefotaxime.
Preferred prophylaxis is with topical 0.5% erythromycin ointment (1-cm ribbon per eye) immediately after birth.
Test (and treat) mother and sexual partner for STDs/sexually transmitted infections (STIs).
Chlamydial Ophthalmia Neonatorum (Trachoma)
Symptoms will show 4 to __ days after birth.
Eye___ become ed_____ and red with profuse _____ discharge initially that later becomes p_____.
When obtaining a sample, collect not only the exudate but also (1) cells. Rule out concomitant chlamydial pn_____.
Treated with ______ antibiotics such as oral _____ base or erythromycin ethylsuccinate QID × 14 days. Treatment only 80% effective. May need second course. Use only _____ antibiotics.
The prophylaxis used for gonococcal ophthalmia (t_____0.5% erythromycin) will not prevent neonatal chlamydial conjunctivitis or extraocular infections, thus the importance of prenatal sc_____ and treatment.
______ disease. Test (and treat) m____ and sexual _____ for STDs.
Symptoms will show 4 to 10 days after birth.
Eyelids become edematous and red with profuse watery discharge initially that later becomes purulent.
When obtaining a sample, collect not only the exudate but also conjunctival cells. Rule out concomitant chlamydial pneumonia.
Treated with systemic antibiotics such as oral erythromycin base or erythromycin ethylsuccinate QID × 14 days. Treatment only 80% effective. May need second course. Use only systemic antibiotics.
The prophylaxis used for gonococcal ophthalmia (topical 0.5% erythromycin) will not prevent neonatal chlamydial conjunctivitis or extraocular infections, thus the importance of prenatal screening and treatment.
Reportable disease. Test (and treat) mother and sexual partner for STDs.
Chlamydial (1)
In infants with ophthalmia neonatorum, also rule out concomitant chlamydial _____.
Obtain n______ culture for chlamydia. Infant will have frequent c_____ with bibasilar r____, tachypnea, hyperinflation, and diffused inf______ on chest x-ray.
Treated with Rx(1) QID × 2 weeks. Daily follow-up. _____ disease.
Chlamydial Pneumonia
In infants with ophthalmia neonatorum, also rule out concomitant chlamydial pneumonia.
Obtain nasopharyngeal culture for chlamydia. Infant will have frequent cough with bibasilar rales, tachypnea, hyperinflation, and diffused infiltrates on chest x-ray.
Treated with erythromycin QID × 2 weeks. Daily follow-up. Reportable disease.
Sudden Infant Death Syndrome
A sudden infant death in apparently h_____ infants
Higher risk with ___maturity, ____birth weight, maternal sm_____ and/or drug use, and poverty.
Cause hypothesized to be a multifactorial convergence of intrinsically vulnerable infant (g______ predisposition) during a critical development period with exogenous st______.
To decrease risk, position infants on their ____ (supine); use a f____ sleep surface; encourage b_____feeding and routine imm______; room share _____ bedsharing; offer a p_____ for sleep times; and avoid soft objects and _____ bedding in the sleep area, sm____ exposure, and over_____ infant.
A sudden infant death in apparently healthy infants <12 months, which cannot be explained after a thorough case investigation that includes a scene investigation, autopsy, and review of clinical history.
Higher risk with prematurity, low birth weight, maternal smoking and/or drug use, and poverty.
Cause hypothesized to be a multifactorial convergence of intrinsically vulnerable infant (genetic predisposition) during a critical development period with exogenous stressors.
To decrease risk, position infants on their backs (supine); use a firm sleep surface; encourage breastfeeding and routine immunizations; room share without bedsharing; offer a pacifier for sleep times; and avoid soft objects and loose bedding in the sleep area, smoke exposure, and overheating infant.
Excessive Weight Loss (>___%)
Newborns are ex______ to lose weight during the first few days of life. Weight loss can vary by feeding method and delivery type; infants delivered by (1) tend to lose a larger percentage of birth weight than their (1)delivered counterparts. ______-fed infants may lose up to 5%, and _____-fed infants may lose 7% to 10% of their birth weight.
Any loss from birth weight should be regained within 10 to ___ days. Weight loss beyond ___% in neonates is considered abnormal. Assess the infant for de_____, el_____disturbances, and hyperbi______, and the mother and infant for lactation difficulties.
Excessive Weight Loss (>10%)
Newborns are expected to lose weight during the first few days of life. Weight loss can vary by feeding method and delivery type; infants delivered by cesarean section (C-section) tend to lose a larger percentage of birth weight than their vaginally delivered counterparts. Formula-fed infants may lose up to 5%, and breast-fed infants may lose 7% to 10% of their birth weight.
Any loss from birth weight should be regained within 10 to 14 days. Weight loss beyond 10% in neonates is considered abnormal. Assess the infant for dehydration, electrolyte disturbances, and hyperbilirubinemia, and the mother and infant for lactation difficulties.
Dehydration
Signs of severe dehydration (>10% weight loss) in an infant are w___ and r____ pulse, ____pnea or deep breathing, par____ mucous membranes, anterior fontanelle that is markedly s____, skin turgor showing t_____, c____ skin, acrocy____, anuria, and change in LOC (lethargy to coma).
Refer severely dehydrated infants to the ___ for (1) hydration. Severe dehydration due to acute g______ is one of the leading causes of death of infants in the developing world.
Signs of severe dehydration (>10% weight loss) in an infant are weak and rapid pulse, tachypnea or deep breathing, parched mucous membranes, anterior fontanelle that is markedly sunken, skin turgor showing tenting, cool skin, acrocyanosis, anuria, and change in LOC (lethargy to coma).
Refer severely dehydrated infants to the ED for intravenous (IV) hydration. Severe dehydration due to acute gastroenteritis is one of the leading causes of death of infants in the developing world.
(1)
Most common type of pigmented skin lesions in newborns. Present in almost all Asians (85%–100%) and in more than half of Native American, Hispanic, and Black neonates. Blue- to black-colored patches or stains. A common location is the lumbosacral area (but can be located anywhere on the body). May be mistaken for bruising or child abuse. Usually fade by age 2 to 3 years.
Congenital Dermal Melanocytosis (Mongolian Spots)
(1)
Most common in neonates. Multiple white 1- to 2-mm papules located mainly on the forehead, cheeks, and nose. Due to retention of sebaceous material and keratin. Resolves spontaneously.
Milia, Miliaria, or “Prickly Heat”
(1)
Small pustules (whitish-yellow color) that are 1- to 3-mm in size and surrounded by a red base. Erupt during the second to the third day of life. Located on the face, chest, back, and extremities. Last from 1 to 2 weeks and resolve spontaneously.
Erythema Toxicum Neonatorum
(1)
Excessive thick scaling on the scalp of younger infants. Treated by softening and removal of the thick scales on the scalp after soaking scalp a few hours (to overnight) with vegetable oil or mineral oil. Shampoo scalp and gently scrub scales with soft comb. Prevention is by frequent shampooing with mild baby shampoo and removing scales with soft brush or comb. Self-limited condition that resolves spontaneously within a few months.
Seborrheic Dermatitis (“Cradle Cap”)
(1)
Tufts of hair overlying spinal column usually at lumbosacral area. May be a sign of neural tube defects (spina bifida, spina bifida occulta). Perform neurologic exam focusing on lumbosacral nerves (fecal/urinary in______, problems with g___). Order (1) of lesion to rule out (1).
Faun Tail Nevus
Tufts of hair overlying spinal column usually at lumbosacral area. May be a sign of neural tube defects (spina bifida, spina bifida occulta). Perform neurologic exam focusing on lumbosacral nerves (fecal/urinary incontinence, problems with gait). Order ultrasound of lesion to rule out occult spina bifida.
(1)
Flat light-brown to dark-brown spots >___ mm (0.5 cm). If ___ or more spots larger than 5 mm (0.5 cm) in diameter are seen, rule out neuro_______or von R_______ disease (e.g., neurologic disorder marked by seizures, learning disorders). Refer to pediatric (1) if the spots meet the same criteria to rule out neurofibromatosis.
Café Au Lait Spots
Flat light-brown to dark-brown spots >5 mm (0.5 cm). If six or more spots larger than 5 mm (0.5 cm) in diameter are seen, rule out neurofibromatosis or von Recklinghausen’s disease (e.g., neurologic disorder marked by seizures, learning disorders). Refer to pediatric neurologist if the spots meet the same criteria to rule out neurofibromatosis.
(1)
A vascular lesion often referred to as “____ bites” or “____ kisses.” Flat pink patches found on the forehead, eyelids, and nape of neck (Figure 1). Usually appear on both sides of the ____line (i.e., on both eyelids or across the entire nape of neck). ____chable, but color changes with crying, breath holding, and room temperature changes. Consider Beckwith–Wiedemann or FAS if glabellar lesion seen. Typically f____ by 18 months.
Salmon Patches (Nevus Simplex)
A vascular lesion often referred to as “stork bites” or “angel kisses.” Flat pink patches found on the forehead, eyelids, and nape of neck (Figure 1). Usually appear on both sides of the midline (i.e., on both eyelids or across the entire nape of neck). Blanchable, but color changes with crying, breath holding, and room temperature changes. Consider Beckwith–Wiedemann or FAS if glabellar lesion seen. Typically fade by 18 months.
(1)
Neonates with pink-to-red, flat, stain-like skin lesions located on the upper and lower eyelids or on the V1 and V2 branches of the _______ nerve (CN V) should be referred to a pediatric ophthalmologist to rule out congenital (1). Blanches to pressure. Irregular in size and shape. Usually unilateral. Large lesions located on half the facial area may be a sign of trigeminal nerve involvement and Sturge–Weber syndrome (rare neurologic disorder). The lesions do _____ regress and grow with the child. These lesions can be treated with (1) (PDL) therapy.
Port Wine Stain (Nevus Flammeus)
Neonates with pink-to-red, flat, stain-like skin lesions located on the upper and lower eyelids or on the V1 and V2 branches of the trigeminal nerve (CN V) should be referred to a pediatric ophthalmologist to rule out congenital glaucoma. Blanches to pressure. Irregular in size and shape. Usually unilateral. Large lesions located on half the facial area may be a sign of trigeminal nerve involvement and Sturge–Weber syndrome (rare neurologic disorder). The lesions do not regress and grow with the child. These lesions can be treated with pulse-dye laser (PDL) therapy.
(1)
Raised vascular lesions ranging in size from 0.5 to 4.0 cm that are bright red in color and feel soft to palpation. Usually located on the head or the neck. The lesions often grow rapidly during the first 12 months of life, but the majority will involute gradually over the next 1 to 5 years. Watchful waiting is the usual strategy. Can be treated with (1) therapy.
Hemangioma (Strawberry Hemangioma)
Raised vascular lesions ranging in size from 0.5 to 4.0 cm that are bright red in color and feel soft to palpation. Usually located on the head or the neck. The lesions often grow rapidly during the first 12 months of life, but the majority will involute gradually over the next 1 to 5 years. Watchful waiting is the usual strategy. Can be treated with PDL therapy.
Vision Screening
Newborn Vision
Newborns are ____-sighted (myopia) and have a vision of 20/400.
They can focus best at a distance of 8 to ___ inches.
During the first 2 months, the infant’s eyes may appear cr_____ (or wander) at times (normal finding). If one eye is consistently turned in or turned out, refer to pediatric ophthalmologist.
Human f____ is preferred by newborns.
Newborns do ___ shed ____ , because the lacrimal ducts are not fully mature at birth.
Caucasian neonates are born with blue-gray eyes. It is normal for their eye color to _____ as they mature.
R_____ (CN II) are immature at birth and reach maturity at age 6 years.
Newborns are nearsighted (myopia) and have a vision of 20/400.
They can focus best at a distance of 8 to 10 inches.
During the first 2 months, the infant’s eyes may appear crossed (or wander) at times (normal finding). If one eye is consistently turned in or turned out, refer to pediatric ophthalmologist.
Human face is preferred by newborns.
Newborns do not shed tears, because the lacrimal ducts are not fully mature at birth.
Caucasian neonates are born with blue-gray eyes. It is normal for their eye color to change as they mature.
Retinas (CN II) are immature at birth and reach maturity at age 6 years.
Infant Screening
Match these descriptions with what an infant’s vision at 1, 3, 6, and 12 months
- (1)**:* Makes good eye contact. Turns head to scan surroundings with 180-degree visual field.
- (1)**:* Infant will hold the hands close to the face to observe them. Hold a bright object or a toy in front of the infant. Watch behavior as the infant fixates and follows the toy for a few seconds. Avoid using objects/toys that make noises when testing vision.
- (1):* Makes prolonged eye contact when spoken to. Will actively turn head around 180 degrees to observe people and surroundings for long periods. Recognizes self in a mirror and parents and favorite people from a longer distance.
- (1)**:* Infant can fixate briefly on the mother’s face. Prefers the human face.
- 6 months:* Makes good eye contact. Turns head to scan surroundings with 180-degree visual field.
- 3 months**:* Infant will hold the hands close to the face to observe them. Hold a bright object or a toy in front of the infant. Watch behavior as the infant fixates and follows the toy for a few seconds. Avoid using objects/toys that make noises when testing vision.
- 12 months:* Makes prolonged eye contact when spoken to. Will actively turn head around 180 degrees to observe people and surroundings for long periods. Recognizes self in a mirror and parents and favorite people from a longer distance.
- 1 month:* Infant can fixate briefly on the mother’s face. Prefers the human face.