Peds GI@ Flashcards

1
Q

T/F: Young children dx with UC or indet colitis usually end up becoming Crohns later

A

True

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2
Q

Sxs of cows milk colitis?

A

Blood and mucous in stool btwn 2-6 wks old, usually no sx of pain or d/c with stooling.

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3
Q

Tx of cows milk colitis?

A

Remove dairy from mom’s diet, use hydrolyzed infant formula

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4
Q

Which kids get more growth fx - Crohns or uC?

A

Crohns - so if UC & growth fx, should ensure not Crohns

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5
Q

T/F: BRAT diet can be useful in viral diarrhea in kids?

A

False - regular diet and ORT is best

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6
Q

What is congenital chloride diarrhea?

A

Polyhydramnios, sec diarrhea, met alk, nl endoscopies - need K and Cl supplementation for life

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7
Q

What is chronic nonspecific diarrhea of childhood (CNSD)

A

Ages 1-3 and last til 5 yo - nonbloody diarrhea, worsens as day goes on, no overnight sxs - may see undigested foods

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8
Q

T/F: Chronic nonspecific diarrhea of childhood (CNSD) is AW wt loss?

A

False

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9
Q

How to tx CNSD?

A

Reassurance

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10
Q

Three criteria for pediatric AP?

A
  1. Abd pain
  2. Elevated A/L > 3x ULN
  3. Imaging of
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11
Q

How does AP differ in kids and adult?

A

Location of pain does not need to be epigastric - can be all over abdomen

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12
Q

Liver bx findings in Alagilles?

A

Intrahepatic cholestasis w paucity of intrahep bile ducts and minimal inflammation

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13
Q

Describe findings in Alagilles syndrome

A

Triangular face, butterfly vert

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14
Q

What genetic defects in Alagilles?

A

Notch2 or JAG1

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15
Q

If suspect Hirschsprung in newborn, what test to do first for workup?

A

If < 39 days old, contrast enema or ARM

If > 39 days old, rectal suction bx (not as good in first 39 days)

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16
Q

What is first step if someone presents with tylenol OD within first 8 hours?

A

Get tylenol, ASA, LFTs - can await tylenol level prior to starting NAC in order to see where pt falls on normogram

17
Q

List sxs in 4 stages of tylenol OD

A

I - 24 hours - anorexia, N/V
II - 24-48 hours - improvement in clinical status but worsened LFTs
III - 48-96 hours - hepatic stage - all sxs an liver fx
IV - 96 hours-2 weeks - recovery phase

18
Q

What is copper quant in Wilsons dz on bx?

A

> 250mcg Cu/g of liver

19
Q

What are sens and spec of celiac ABs?

A

> 95% each

20
Q

If tx needed, what can be used to tx giardia?

A

Metro, quinacrine, paromycin, or furazolidone

21
Q

T/F: Pt with DM1 may get annual TTG testing due to high risk of celiac dz.

A

True

22
Q

T/F: Kids usually dx with colitis, however, as they age it becomes apparent they have Crohns.

A

True

23
Q

T/F: Kids with IBD at young age tend to have a less severe course than adult onset.

A

False, have a more severe course

24
Q

Which (UC or CD) is growth failure associated with in kids?

A

CD - if dx with UC and growth fx consider if it is correct dx

25
Q

What formula should be used in kid with cows milk protein allergy? What % of the time is this tx not successful?

A

Casein hydrosylate formula; not successful 5% of the time

26
Q

What is cryoheptadine?

A

An antihistamine - can be used for functional abdominal pain in children

27
Q

T/F: GER is normal in babies

A

True - usually peaks at 4 months and better at 1 year

28
Q

Triad of HUS

A

MAHA, AKI, thrombocytopenia

29
Q

T/F: C jejuni frequently leads to chronic diarrhea in kids.

A

False, very common cause of acute but no evidence that leads to chronic diarrhea

30
Q

What is congenital chloride diarrhea?

A

Defect in chloride-bicarb exchanger in SI - leads to diarrhea with metab alk that does not improve even with dietary milk changes

31
Q

Congenital chloride diarrhea is the only congenital diarrhea to cause what?

A

Metab alkalosis

32
Q

What is tx of cong chloride diarrhea?

A

Sodium chloride and potassium chloride supplementation

33
Q

What are sxs of FPIES?

A

Intermittent emesis, diarrhea, weight loss in infancy

34
Q

What are MC triggers of FPIES?

A

Milk, soy, oats

35
Q

What will bx of colon/SI show in FPIES?

A

Eosinophils

36
Q

Within what time frame of life should you not test for Cdiff as it will be normal flora and not cause sxs?

A

<1 year of age

37
Q

List sxs of vit E def

A

Hyporeflexia, loss of propioception, gait abnormal, abnl hand and eye mvmts

38
Q

For biliary atresia, at what point is Kasai preferred over liver transplant as kids tend to do better?

A

Less than 60 days of age

39
Q

Liver fx and hypoglycemia point to what?

A

inborn errors of metabolism - test acylcarnitine profile