Female Dz@ Flashcards

1
Q

“Central scar” on CT liver mass

A

FNH

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2
Q

Should OCPs be d/c’ed in pts with FNH?

A

No, inc risk of getting it but no need to dc

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3
Q

What s/s of intraheptic cholestasis of preg?

A

Elevated LFTs, severe pruritis, normal GGT

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4
Q

How to confirm ICP?

A

Bile acid levels

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5
Q

When to dc infliximab in preg?

A

8-10 weeks before deliveru

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6
Q

How to treat endometriosis pain?

A

OCPs

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7
Q

MC demographic to get serous cystadenoma?

A

Female > 60 yo

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8
Q

“Central scar” in panc lesion

A

serous cystadenoma

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9
Q

Describe differences in sampling of MCN and serous Cystad?

A

MCN - mucin secreting cuboidal epithelium

SCA - glycogen containing cuboidal epith

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10
Q

CEA in SCA vs MCN?

A

MCN usu >200, SCA low

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11
Q

SEs of linaclotide vs lubiprostone?

A

Linac - HA
Lubi - N, edema, chest dc, SOB
Both - Diarrhea, abd pain/dist, incontinence

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12
Q

What class is linaclotide and lubiprostone?

A

Linac (Linzess) - GC2C agonist - stims Cl, HCO3, H2O into colon
Lubi (Amitiza) - activates ClC-2 chloride chanels and inc secretion

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13
Q

Rates of fertility of UC pts before and after IPAA?

A

Before - gen pop (15%)

After - 1/2 of gen pop

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14
Q

IHCP tx

A

Urosdiol

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15
Q

What risk to baby in IHCP?

A

Prematurity, stillbirth, meconium staining

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16
Q

What ABs to check if considering scleroderma?

A

Anti topoisomerase I, anticentromere, ANA, ANti-RNA Poly III

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17
Q

Anti CCP in what dz?

A

RA

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18
Q

Diff in anti TopoIso and centromere?

A

TI - Scleroderma

CM - CREST

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19
Q

Which progression should be made when treating GERD in pregnancy?

A

Start with lifestyle modification and Ca carb, can then add H2B, then PPI if needed

20
Q

T/F: Sodium bicarb is a safe antacid during pregnancy.

A

False, can lead to metab alk and fluid overload

21
Q

Pt with fecal urge incontinence likely have defect in what?

22
Q

Pt with incontinence without urge likely have defect with what?

23
Q

What is best mgmt of urge incontinence?

A

Biofeedback therapy + PFR > PFR alone

24
Q

T/F: Biofeedback is effective for IAS defect leading to incontinence.

25
What criteria need to be met to dx PBC?
2/3 - elevated alk phos, + AMA, bx with nonsuppurative destruction of intralobular bile ducts
26
T/F: FNH, which has a typical pattern of central scar on imaging, should be treated by d/c contraceptives if on them
False, all is true but tx is reassurance, no need to d/c OCPs in most cases
27
Which type of liver mass should be resected prior to pregnancy due to risk of rupture by hormone induced growth?
Hepatic adenoma - usu in pts with long term OCP use
28
How to confirm Intrahepatic cholestasis of pregnancy?
Check bile acid levels - should be very high
29
What is tx of ICP?
Ursodiol & delivery at 36-37 weeks
30
How to differentiate HELLP from AFLP?
HELLP more likely to have HTN | AFLP more likely to have hypoglycemia, inc PT/PTT, elevated Cr
31
What factors put mom at high risk of transmitting hep B to baby?
HBeAg+ and high DNA
32
What to do for baby born to HBV+ mom?
HBIG and hep B vaccine within 12 hours of birth
33
Mom with high HBV DNA - what should be done for tx to px spread to baby?
Antivirals starting 6-8 weeks prior to delivery
34
T/F: E/P decreases risk of CRC in women.
true
35
T/F: If women gets pregnant within one yr of liver TP, has inc risk of rejection during preg.
true
36
Serous cystadenoma findings
Female > 60, central scar on imaging, low CEA and amylase, glycogen rich on cytology
37
Which hormone increases LES relaxation in pregnancy leading to reflux?
Progesterone
38
What is MC type of constipation?
Slow transit constipation, especially in young F with chronic constipation
39
Name 4 main factors AW fecal incontinence in pts after delivery.
Fecal wt > 4g Forceps delivery Length of 2nd stage of labor 3rd or 4th degree perineal tear
40
T/F: PBC pts should have BMD testing at time of diagnosis and every 2 years following
True
41
Pts homozygous for what gene at risk of AFLP?
LCHAD
42
What is fertility rate for medically treated UC vs IPAA?
Tx UC - 85% | IPAA - 55%
43
T/F: Hyperemesis gravidarum can lead to elevated LFTs.
True - but typically get better with rehydration
44
T/F: IHCP has a risk of premature delivery.
True
45
T/F: MTX CI in preg but safe when breastfeeding
False, should not use in both cases
46
How to tx listeria?
Ampicillin