Female Dz@ Flashcards

1
Q

“Central scar” on CT liver mass

A

FNH

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2
Q

Should OCPs be d/c’ed in pts with FNH?

A

No, inc risk of getting it but no need to dc

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3
Q

What s/s of intraheptic cholestasis of preg?

A

Elevated LFTs, severe pruritis, normal GGT

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4
Q

How to confirm ICP?

A

Bile acid levels

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5
Q

When to dc infliximab in preg?

A

8-10 weeks before deliveru

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6
Q

How to treat endometriosis pain?

A

OCPs

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7
Q

MC demographic to get serous cystadenoma?

A

Female > 60 yo

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8
Q

“Central scar” in panc lesion

A

serous cystadenoma

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9
Q

Describe differences in sampling of MCN and serous Cystad?

A

MCN - mucin secreting cuboidal epithelium

SCA - glycogen containing cuboidal epith

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10
Q

CEA in SCA vs MCN?

A

MCN usu >200, SCA low

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11
Q

SEs of linaclotide vs lubiprostone?

A

Linac - HA
Lubi - N, edema, chest dc, SOB
Both - Diarrhea, abd pain/dist, incontinence

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12
Q

What class is linaclotide and lubiprostone?

A

Linac (Linzess) - GC2C agonist - stims Cl, HCO3, H2O into colon
Lubi (Amitiza) - activates ClC-2 chloride chanels and inc secretion

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13
Q

Rates of fertility of UC pts before and after IPAA?

A

Before - gen pop (15%)

After - 1/2 of gen pop

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14
Q

IHCP tx

A

Urosdiol

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15
Q

What risk to baby in IHCP?

A

Prematurity, stillbirth, meconium staining

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16
Q

What ABs to check if considering scleroderma?

A

Anti topoisomerase I, anticentromere, ANA, ANti-RNA Poly III

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17
Q

Anti CCP in what dz?

A

RA

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18
Q

Diff in anti TopoIso and centromere?

A

TI - Scleroderma

CM - CREST

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19
Q

Which progression should be made when treating GERD in pregnancy?

A

Start with lifestyle modification and Ca carb, can then add H2B, then PPI if needed

20
Q

T/F: Sodium bicarb is a safe antacid during pregnancy.

A

False, can lead to metab alk and fluid overload

21
Q

Pt with fecal urge incontinence likely have defect in what?

A

EAS

22
Q

Pt with incontinence without urge likely have defect with what?

A

IAS

23
Q

What is best mgmt of urge incontinence?

A

Biofeedback therapy + PFR > PFR alone

24
Q

T/F: Biofeedback is effective for IAS defect leading to incontinence.

A

False

25
Q

What criteria need to be met to dx PBC?

A

2/3 - elevated alk phos, + AMA, bx with nonsuppurative destruction of intralobular bile ducts

26
Q

T/F: FNH, which has a typical pattern of central scar on imaging, should be treated by d/c contraceptives if on them

A

False, all is true but tx is reassurance, no need to d/c OCPs in most cases

27
Q

Which type of liver mass should be resected prior to pregnancy due to risk of rupture by hormone induced growth?

A

Hepatic adenoma - usu in pts with long term OCP use

28
Q

How to confirm Intrahepatic cholestasis of pregnancy?

A

Check bile acid levels - should be very high

29
Q

What is tx of ICP?

A

Ursodiol & delivery at 36-37 weeks

30
Q

How to differentiate HELLP from AFLP?

A

HELLP more likely to have HTN

AFLP more likely to have hypoglycemia, inc PT/PTT, elevated Cr

31
Q

What factors put mom at high risk of transmitting hep B to baby?

A

HBeAg+ and high DNA

32
Q

What to do for baby born to HBV+ mom?

A

HBIG and hep B vaccine within 12 hours of birth

33
Q

Mom with high HBV DNA - what should be done for tx to px spread to baby?

A

Antivirals starting 6-8 weeks prior to delivery

34
Q

T/F: E/P decreases risk of CRC in women.

A

true

35
Q

T/F: If women gets pregnant within one yr of liver TP, has inc risk of rejection during preg.

A

true

36
Q

Serous cystadenoma findings

A

Female > 60, central scar on imaging, low CEA and amylase, glycogen rich on cytology

37
Q

Which hormone increases LES relaxation in pregnancy leading to reflux?

A

Progesterone

38
Q

What is MC type of constipation?

A

Slow transit constipation, especially in young F with chronic constipation

39
Q

Name 4 main factors AW fecal incontinence in pts after delivery.

A

Fecal wt > 4g
Forceps delivery
Length of 2nd stage of labor
3rd or 4th degree perineal tear

40
Q

T/F: PBC pts should have BMD testing at time of diagnosis and every 2 years following

A

True

41
Q

Pts homozygous for what gene at risk of AFLP?

A

LCHAD

42
Q

What is fertility rate for medically treated UC vs IPAA?

A

Tx UC - 85%

IPAA - 55%

43
Q

T/F: Hyperemesis gravidarum can lead to elevated LFTs.

A

True - but typically get better with rehydration

44
Q

T/F: IHCP has a risk of premature delivery.

A

True

45
Q

T/F: MTX CI in preg but safe when breastfeeding

A

False, should not use in both cases

46
Q

How to tx listeria?

A

Ampicillin