Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Gastro Review > Pancreas@ > Flashcards

Pancreas@ Flashcards

1
Q

At what timeframe do acute panc collections become WON or pseudocyst?

A

4 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What stimulates panc secretion?

A

inc permeability of apical Cl/HCO3 channels through cAMP & Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: VIP and secretin stim panc secretion by inc cAMP

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which substances inc panc secretion by increasing Ca?

A

Gastrin releasing peptide (GRP), subst P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MC presentation of MCN?

A

Unilocular, body or tail, middle aged F

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

This panc lesion typically multilocular with central stellate calcifications?

A

Serous cystadenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ovarian stroma on path in what?

A

MCN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F: All IPMNs have some type of duct communication?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the most potent sti of secretin release by duodenal S cells?

A

Duod pH < 4.5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which type of FA can stim secretin release?

A

LCFA (oleate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is T2 AI panc?

A

idiopathic, duct centric pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which type of AI panc responds better to steroids?

A

Type 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T/F: Relapses with T2 AI panc are common?

A

False, they are rare

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which type of AI panc has elevated IgG4?

A

Type 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Path of type 2 AI panc bx?

A

Periductal inflammation and granulocyte epithelial lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which defect causes AD calcific hered pancreatitis?

A

PRSS1 gain of fcn mut

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

T/F: CFTR is transmitted in AD fashion?

A

False, AR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which defect causes “tropical panc”?

A

SPINK1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

T/F: If suspected infected panc necrosis, abx and conservative mgmt should be tried first.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is MC NET with MEN1?

A

Gastrinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

MEN2a risks

A

Thyroid, adrenal, PT adenomas (PAT)

22
Q

What is pancreatic panniculitis AW?

A

Panc acinar cell carcinoma

23
Q

What is minimum dose of panc enzymes to tx steatorrhea

A

30,000 IU

24
Q

T/F: PPI can be used as a primary tx to tx steatorrhea in CP.

A

False, can be used as adjunct but not primary tx

25
Q

What is Shwachman-Diamond syndrome?

A

AR dz that can cause panc insufficiency in kids (2nd MC after CF), BM fx w neutropenia –> infxns, short stature

26
Q

What MAL are SDS pts at risk for?

A

MDS and AML

27
Q

Age groups for T2 and T1 AIP?

A

T1 ~ 60 yo

T2 ~ 40 yo

28
Q

Which AIP is AW IgG4 dz?

A

Type 1

29
Q

Granulocyte epithelial lesion

A

Type 2 AIP

30
Q

T/F: Type 2 AIP not AW extrapanc dz?

A

True

31
Q

What is T2 AIP recurrence rate after steroids?

A

< 10%

32
Q

What activates panc enzymes and defect in it is associated with tropical pancreatitis?

A

Trypsin

33
Q

T/F: Pt swith chronic panc and exocrine insuff are at inc risk of SIBO

A

True

34
Q

Pt with disabling pain in chronic panc, dilated duct, no further alc use - what is best tx to improve QOL over next 5 yrs?

A

Peustow

35
Q

List groups of pts that need panc CA screening.

A
  • 2 FDRs
  • Lynch with 1 FDR
  • BRCA2
  • FAMM syndrome
  • Peutz-Jeghers syndrome
36
Q

Pts with panc AC are absolute CI to surgical resection if invasion of what vessel?

A

SMA

37
Q

MCC of hereditary panc is what?

A

Gain of fcn of cationic trypsinogen gene (PRSS1)

38
Q

MEN1 can lead to what?

A

HyperPTH, ZES, hypercalcemia, NET (HeNZ)

39
Q

Type 1 vs type 2 AIP histo.

A

Type 1 - Lymphoplasmacytic sclerosing pancreatitis

Type 2 - Duct centric pancreatitis

40
Q

Rate of relapse after steroids for T1 AIP?

A

20-60%

41
Q

Which factors inc risk of post ERCP panc?

A 
Young age
Female
Normal LFTs/imaging
Multiple cannulation attempts or forceful cannulation
Repeated panc injections
Precut sphincterotomy
Panc sphincterotomy
Low case volume endoscopist
42
Q

Which med can decrease opioid need in chronic panc?

A

Pregabalin

43
Q

If AIP leads to obstructive jaundice, consider which type?

A

Type 2

44
Q

T/F: T1 AIP is AW IBD.

A

False, type 2

45
Q

Typical IgG4 dz pt presentation affects which organs

A

Bile duct, panc, salivary glands

46
Q

IgG4 AI panc usually has what panc and panc duct findings?

A

Narrowed, not enlarged or dilated duct with diffusely enlarged panc

47
Q

What are characteristic findings of glucagonoma?

A

Rash (necrolytic migratory erythema), high glucose

Dystrophic nails, alopecia, angular chelitis

48
Q

How to dx glucagonoma?

A

High serum glucagon (>500), CT/MR with findings, consider PET or gad scan

49
Q

How to tx glucagonoma?

A

Surg if possible, SS analogues can help

50
Q

T/F: PPX anticoag should be done in pts with glucagonoma due to high risk of DVT/PE.

A

True

Gastro Review (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions