Pedia 3B Virology Flashcards
Mild rhinorrhea w/sneezing ff-ed by
wheezy cough and progressive resp distress
Ausc: diffuse rhonchi crackles and wheezes
Pharyngo-conjunctival fever (Adeno) Laryngo-tracheo-bronchitis (Parainfluenza) Herpangina (Cox A) Bronchiolitis (RSV) * Influenza
Low grade fever
Colds for 1-3 days
Barking cough, hoarseness and INSP stridor
Pharyngo-conjunctival fever (Adeno) Laryngo-tracheo-bronchitis (Parainfluenza) * Herpangina (Cox A) Bronchiolitis (RSV) Influenza
Fever, drooling of saliva
Vesicles and ulcers over the anterior pillars, soft palate, uvula and tonsils
Pharyngo-conjunctival fever (Adeno) Laryngo-tracheo-bronchitis (Parainfluenza) Herpangina (Cox A) * Bronchiolitis (RSV) Influenza
Abrupt onset of high fever, coryza, conjunctivitis, pharyngitis and dry cough
Accompanied by malaise, myalgia and headache
Pharyngo-conjunctival fever (Adeno) Laryngo-tracheo-bronchitis (Parainfluenza) Herpangina (Cox A) Bronchiolitis (RSV) Influenza *
Fever w/pharyngitis, non-purulet conjunctivitis, pre-auricular and cervical lymphadenopathy
Pharyngo-conjunctival fever (Adeno) * Laryngo-tracheo-bronchitis (Parainfluenza) Herpangina (Cox A) Bronchiolitis (RSV) Influenza
Hepatitis A-E
Communicability is highest during first 2 weeks BEFORE onset of symptoms
A
Hepatitis
Acute fulminant hepatitis occurs more frequently
B + D
Hepatitis
Associated w/ extra-hepatic manifestations
B & C
Hepatitis
Most likely to cause chronic infections w/primary HCC after 2-3 decades from infection
C
Hepatitis
Co-infection and superinfection must exist for infection to occur
B + D
Hepatitis Markers
Acute, chronic infection or resolved infection
Anti-HBc
Hepatitis Markers
Lower risk of transmitting infection
Anti-HBe
Hepatitis Markers
INC risk of transmitting infection
HBe Ag
Hepatitis Markers
Resolved infection and immunity acquired from immunization
Anti-HBs
Hepatitis Markers
Acute or chronic infection
HBs Ag
Hepatitis
highly communicable via stool during first 2 weeks before onset of symptoms
A
Hepatitis
highly infectious for as long as the patient is positive for its antigen
B
Hepatitis
Primary HCC after 20-30 years
C
INC serum amylase
Assoc w/pancreatitis
Mumps
Usually no prodrome
Dx via appearance of rash
Rubella (German Measles)
Prodrome 2-4d high fever, myalgia, cough, pleuritic chest pain and weakness
Atypical measles ??
Prodrome of 3-5 days
Cephalocaudal rash
Measles
High grade fever for 3 days ff-ed by rash
Roseola infantum
Slapped cheek appearance
Erythema infectiosum (Parvo)
Lesions appear as crops
Varicella
Vesicular lesions distributed along innervations
Zoster
Papulo-vesicular lesions
Both varicella and zoster
Marker for Hep B infection
HBsAg
Hepatitis marker
Immunity through previous infection/vaccination
Anti-HBs
Hepatitis Marker
Active viral replication and infectivity
HBeAg
Diagnostic Test
Congenital CMV infection
Urine culture
Diagnostic Test
HSV encephalitis
CSF DNA PCR
Diagnostic Test
Poliomyelitis
Stool culture
Diagnostic Test
EBV Infectious mononucleosis
IgM VCA
Diagnostic Test
HIV infection
Western blot
MC 1’ manifestation of HSV
Herpetic Gingivostomatosis
MC 2’ (Reactivation) of HSV
Herpes labiales
Clinical manifestation of CMV
Jaundice
Chorioretinitis
Microcephaly
IUGR
Triad of EBV
Splenomegaly
Exudative pharyngitis
Lymphadenopathy
Virus assoc w/Burkitt’s lymphoma and Hodgkin’s Dse
EBV
Rash characterized by evolution of all stages starting from the trunk spreading to different parts of the body
Varicella
Rash is discrete maculopapules on the face becoming generalized in 24 hours w/minimal desquamation
Rubella (German measles)
Rash is discrete maculopapules appearing on the trunk spreading to neck and extremities w/defervesence EXanthema pattern
Sixth disease (Roseola)
Rash is initially erythematous facial flushing speading to the trunk as diffuse macular erythema w/central clearing
Fifth disease/Erythema infectiosum/Parvovirus B19
Rash is maculopapular in cephalocaudal progression w/hyperpigmentation and desquamation
Rubeola (Measles)
Fetal infection may result to intrauterine fetal death or fetal hydrops
Roseola
Contagious or Non-contagious
Erythema infectiousum before the rash
Contangious
Contagious or Non-contagious
5th day of rashes in measles
Contagious
Contagious or Non-contagious
8th day of rashes in chicken pox all dried and crusted
Non-contagious
Contagious or Non-contagious
Parotid swelling for 6 days
Non-contagious
>24 hours before swelling
Later than 3 days after swelling subsides
Contagious or Non-contagious
8m baba w/congenital rubella
Non-contagious
HIV Category (I, II, III) REcurrent gingivitis or otitis media
Mild I
HIV Category (I, II, III) Recurrent non-typhoidal sepsis
III SEVERE
HIV Category (I, II, III) Chronic diarrhea
Moderate II
Rabies Post-exposure prophylaxis
Contact w/ droplets of saliva of rapid patient
RIG
Active vaccination
Rabies Post-exposure prophylaxis
Superficial scratch or abrasion by a dog w/o bleeding
Vaccine
DHF Grade (I-IV) Petechiae on legs
?
DHF Grade (I-IV) Ascites/Pleural effusion
?
DHF Grade (I-IV) Imperceptible BP
IV
DHF Grade (I-IV) Pulse pressure <20 mmHg
III
Rash appears 7-10 days after brief, non-specific febrile illness
Erythema toxicum
Temperature increases as rash appears and will be normal once rash are down legs and feet
Measles
Fever may be absent or low grade and coincides w/appearance of discrete pinkish maculopapules on face, spread rapidly over the entire body and clears by 3rd day w/minimal desquamination
Roseola
Recrudescence of fever may be noted when the lesions get secondarily infected
Varicella
Fever, drooling of saliva, vesicles, ulcers on anterior pillars, soft palate, uvula, tonsils
Herpangina
Scattered vesicles on oropharynx and maculopapules vesicles and or pustures on fingers, hands buttocks and feet
Hand food and mouth disease
Fever, ulcers on gingival mucus membranes, peri-oral vesicles and submandibular adenitis
Gingivostomatitis