PD Treatment- Anticholinergics

Question 1

Anticholinergic drugs used in PD

Answer 1

benztropine and trihexyphenidyl

Question 2

When are anticholinergics used in PD?

Answer 2

Tremor/tremor predominant PD in younger patients

Question 3

Reason anticholinergics aren’t used in the elderly

Answer 3

The side effect profile and they’re both on the BEERS list! They’re associated with a possible link to cognitive impairment and decline

Question 4

Side effects of benztropine and trihexyphenidyl

Answer 4

Mydriasis, dry mouth/skin, urinary retention, constipation, fever, depressed/agitated mental state, flushed skin