PCOL LAB

Question 1

The Group A will serve as

Answer 1

Control Group

Question 2

The Group B will serve as

Answer 2

Positive Group

Question 3

In Analgesic property, what temp. should be set when placing the test animals in the hot apparatus

Answer 3

55-60°C

Question 4

In Analgesic property, what responses are taken after placing the test animal on a hot plate where time are recorded afterwards.

Answer 4

Jumping, Withdrawal of the paws, and Licking of the paws

Question 5

In Analgesic property, what route of Administration is use in the computation dose of the drug

Answer 5

Orally, Subcutaneously, and IP

Question 6

In Analgesic property, what group you will administer the computed dose of the drug

Answer 6

Group B

Question 7

Has been described by International Association for the study of Pain as an “unpleasant sensory and emotional expressions associated with actual or potential tissue damage, or described
in terms of such damage”.

Answer 7

Pain

Question 8

first treated with non – narcotic analgesic

Answer 8

Pain

Question 9

Pain is first treated with

Answer 9

non – narcotic analgesic

Question 10

IASP stands for

Answer 10

International Association for the Study of Pain

Question 11

A substance used to relieve pain.

Answer 11

Analgesic

Question 12

Examples of analgesic agent

Answer 12

• Aspirin
• Acetaminophen
• Indomethacin
• Naproxen

Question 13

A condition in which there is a rise in body temperature above the normal that is 37ºC.

Answer 13

Fever

Question 14

Average body temperature

Answer 14

37ºC

Question 15

Normal body temperature can range between

Answer 15

97 F (36.1 C) and 99 F (37.2 C)

Question 16

Fever is accompanied by

Answer 16

• Shivering
• Headache
• Nausea
• Constipation
• Diarrhea

Question 17

Fever is usually due to

Answer 17

BACTERIAL or VIRAL INFECTIONS and can accompany any infectious disease

Question 18

Drug that prevent or reduce fever by lowering the body temperature.

Answer 18

Antipyretics

Question 19

The one likely to be affected by Antipyretic drugs

Answer 19

Thermoregulatory center of the brain

Question 20

Common examples of Antipyretics

Answer 20

Paracetamol and Aspirin

Question 21

Inflammation is characterized by the orderly occurrence of several processes

Answer 21

1. Initiation
2. Recruitment
3. Chemoattraction of inflammatory cells and activation of these cells to release inflammatory mediators capable of damaging or killing an invading microbe or tumor.

Question 22

The classical signs of inflammation are

Answer 22

• Redness
• Swelling
• Heat
• Pain
• Loss of function

Question 23

In Analgesic property, how long should you wait for the administered drug to take effect

Answer 23

30-45 mins.

Question 24

In Analgesic property, what temp. should be set when placing the test animals again on the hot plate apparatus

Answer 24

55ºC

Question 25

In every property, the final step is tabulating and interpreting the results by creating a

Answer 25

Graphical representation (Bar or line graph)

Question 26

In Analgesic property, place again the test animals on the hot plate apparatus with a temperature of 55°C every other ___ for ___

Answer 26

5 mins for 20 mins.

Question 27

In Antipyretic property, the baseline temperature must be

Answer 27

Recorded first

Question 28

In Antipyretic property, how much should you administer when using Brewer's yeast

Answer 28

0.5 mL

Question 29

In Antipyretic property, what route of parenteral injection should you administer the Brewer's yeast

Answer 29

Intramuscular

Question 30

In Antipyretic property, what is the waiting time after you administer the Brewer's yeast

Answer 30

15-20 mins

Question 31

In Antipyretic property, if no notable increase of temperature observed you should Administer another ___ of Brewer’s yeast

Answer 31

0.5 mL

Question 32

In Antipyretic property, you should only administer the computed medication required when

Answer 32

When the body temperature of the test animal increases with comparison to the baseline temperature

Question 33

In Antipyretic property, how long should you wait when you administer the computed medication required

Answer 33

45-60 mins

Question 34

In Antipyretic property, what group should you administer the computed medication required

Answer 34

Group B

Question 35

In Antipyretic property, temperature must be taken again every after ____ for ___

Answer 35

15 mins for 1 hour

Question 36

What test animals you should group in Anti-inflammatory property

Answer 36

Rattus norvegicus

Question 37

What test animals you should group in Antipyretic property

Answer 37

Oryctolagus cuniculus

Question 38

What test animals you should group in Analgesic property

Answer 38

Mus musculus albinus

Question 39

In Anti-inflammatory property, what paw you should measure

Answer 39

Right hind paw

Question 40

In Anti-inflammatory property, what tool should you use in measuring the paw

Answer 40

Vernier caliper

Question 41

In Anti-inflammatory property, how much should you administer when using Carrageenan

Answer 41

0.1 mL

Question 42

In Anti-inflammatory property, what route of parenteral injection should you administer the Carrageenan

Answer 42

Subcutaneous

Question 43

In Anti-inflammatory property, what is the waiting time after you administer the Carrageenan

Answer 43

15-20 mins

Question 44

In Anti-inflammatory property, how long should you wait for the administered drug to take effect

Answer 44

20-30 mins

Question 45

In Anti-inflammatory property, measure again the inflamed paws every after __ for ___

Answer 45

15 mins for 1 hour.