Pcm III Flashcards
Head/neck
T1-T4
Heart lungs
T1-T6
Upper GI
T5-T9
Upper GI
T5-T9
SI and R colon
T10-T11
Appendix
T12
L colon and pelvis
T12-L2
Adrenal
T10-T11
GU tract
T10-L2
Ureter-upper/lower
T10-T11/T12-L2
Bladder
T12-L2
UE
T2-8
LE
T11-L2
Most accurate place for saint enting
Forehead
Acute phase reactants
Increase in concentration of serum proteins accompany inflammation and tissue injury
Acute phase reactants with acute or chronic inflammation
Both —infection, trauma, infarction, autoimmune, neoplasms
What are acute phase reactants
Proteins whose serum concentrations increase or decrease by at least 25% during inflammatory states
Increase acute phase reactants
ESR, CRP, ferritin, WBC< haptoglobin, ceruloplasmin
Negative decrease APR
Albumin, transferrin
What is reactive thrombocytopenia
Thrombocytosis in the absence of a chronic myeloproliferative or Myelodysplasia disorder, in patients who have a medical or surgical conditionslikely to be associated with an increased platelet count and in whom the platelet count normalizes, or is expected to normalize after resolution of this condition.
When get thrombocytosis I
Surgery, infection, trauma
Prerenal
Dehydration BUN up
KDIGO for AKI-there are several criteria
Increase in serum creatinine of >.3 mg/dL within 48 hours of >50% within 7 days
Or
Urine output of 6 hours
Signs of hyperkalemia >7
Weak ventricular arrhythmias
Early treatment HyperK
ECG and place on hyperkalemia cardiac monitor
Give calcium gluconate over 2-3 min
Give insulin and glucose followed by dextrose
Hemodialysis
Diuretics
When give catheter
Acute urinary retention or bladder obstruction
Need accurate measurements of urinary output in critically ill patients
Perioperative use for selected surgical procedures
Healing assist in perineal wound in incontinent patient
Prolonged immobilization
Improve comfort
Who not give catheter
Nursing home residents
Only when necessary
Remove as soon as possibly within 24 horus
To get test when patient can voluntarily void
For prolonged post op duration without appropriate indications
In utero atrophic kidney
Vascular event, urinary tract abnormalities (posterior valves, VUR, uteropelvic jucntion obstruction, ACEI, hyperglycemia/DM of mom, Vitamin A defiency, intrauterine growth retardation
First year of life renal hypoplasia
Persistent anorexia and vomiting, failure to thrice
After first year renal hypoplasia
Frequent pyelonephritis, other disorders that lead to renal scarring and ESRD
Indications for dialysis
Fluid overload refractory to diuretics
Hyperkalemia >6 or rapidly rising K levels
Metabolic acidosis
Pericarditis, neuropathy, mental status down
Systemic inflammatory response syndrome
2 or more of the following
Fever
HR up
RR up
White blood cell up
Sepsis
Systemic response to an infection defined by 2 or more SIRS criteria as a result of an infection
Severe sepsis
Sepsis association with organ dysfunction , hypoperfusion or hypotension
Septic shock
Sepsis induced hypotension despite adequate fluid resuscitation along with presence of perfusion abnormalities
Multiple organ dysfunction
Presence of altered organ dysfunction in an acutely ill patient
Most common honeymoon cystitis
Staph saphrophyticus
Kidney viscera somatic
T10-T11
Woman with kidney questions
Last menstrual period
Pregnancy
Contraception
Begin to think of G and P
Gravidity-number of times a woman has been pregnant
Parity-reg led to birth at or beyond 20 weeks or infant more than 500 g
Sympathectomy kidney
T10-L1
Causes vasoconstriction, ureteroconstriction, constricts internal urethral sphincter
Parasympathetics kidney
Vagus
Peristalsis and contract
Para ureter
Upper half vagus
Lower half s2-s4
Contract
Bladder para
S2-s4
Contract
Normalize symptomatic crone
ME, ST< MFR< HVLA< rib raising, paraspinal inhibition
Chapman adrenal
2 inch above 1 lateral to umbilicus
Intertransverse spaces between T11-T12
Kidney ureter chapman
1 inch above 1 inch lateral to umbilicus
Intertransverse space between T12-L1
Bladder chapman
Periumbilical umbilical
Intertransverse spaces between L1-L2
Urethra chapman
Inner edge of pubic ramus near symphysis
L2 TP superior edge
Lymphatics kidney
Clearing bacterial and resulting inflammation
Increased SNS can alter lymph flow, tissue congestion and resultant edema
Congestion in lymphatics can encourage bacterial overgrowth, further contributing t systemic sepsis
Treat lymphatics can be applied to help circulate fluid in the body
Treat thoracic inlet, thoracoabdominal diaphragm, lower robes, pelvic diaphragm, pedal pump
Hemorrhoids
Painless bleeding
Anal fissure
Tearing pain with poop and
Diverticula bleed
Painless profuse bleeding
IBD
UC>crohn
Infectious colitis
Similar clinical rpesentationa nd endoscopic appearance to UC, excluded with stool and tissue cultures, stool studies, and on biopsies of the colon (EHEC)
Ischemic colitis
Abdominal pain followed by profuse bleeding
AV malformation
Ok
Rapid upper GI bleed
Ok
Polyps
Asymptomatic and are most often detected by colon cancer screening tests, occult bleeding
Prostatis
Insidiously and intermittent rectal bleeding , passage of mucus, and mild diarrhea associated with fewer than four small loose stools per day
Rectal ulcer
Can present with bleeding, passage of mucus, straining during defectaiona Nd a sense of incomplete evacuation
Colorectal cancer
Ok
Radiation colitis
Seen weeks to years after abdominal or pelvic irradiation
What meds watch for that are associated with bleeding or may impair coagulation
NSAIDS, anticoagulants, antiplatelet
PE GI signs of hypovolemia
Mild to moderate hypovolemia: resting tachycardia
Blood volume loss of at least 15%: orthostatic hypotension (a decrease int he systolic bp of more than 20mmHg and/or an increase in heart rate of 20 bpm when moving from recumbency to standing_
Blood volume loss of at least 40%: supine hypotension
General GI exam
Cardio, skin, ab, digital rectal exam
Stop smoking
UC
Start smoking
Crohns flair and continued smoking poorer prognosis
BUN CR of UDO bleed
30:1
AST ALT alcoholic
2:1
Anatomical division of upper GIB vs lower GI bleed
Ligament of treitz
What abruptly stopping a beta blocker can lead to
Rebound sinus tachycardia
What diagnostic study should be performed in any female of child bearing age with abdominal pain
Pregnancy test (urine or serum)
How fast can KCL be given through a peripheral IV
10mEq per hour (other it is irritation to the vein)
How many g/dL would you expect the hemoglobin to raise from 1 unit of packed packed RBC
Giving 1 unit of PRBC should increase Hgb by 1g/dL
During an acute IBD flare, what is the primary treatment
Corticosteroids
Recognize erythema nodosum
Immune
IBD
Initial management of acute lower GI bleed
Supportive: IV access, appropriate setting (outpatient/inpatient/ICU), O2, IVF, blood products, assessment and management of coagulopathies
In patients with ongoing bleeding or high risk clinical features
- a colonoscopy should be done within 24 hours of presentation after adequate colon preparation to potentially improve diagnostic and therapeutic yield
- perform colonoscopy as soon as the patient has been resuscitatied and an adequate bowel preparation (4-6 L polyethylene glycol) has been given). (Nasogastric tube may help with getting the prep down)
Considerations for blood transfusion with packed RBS
First type and screen if hemoglobin is stable and no acute bleed
Type and cross
- young patients without comorbid illness may not require transfusion until the hemoglobin <7 g/dL
- older patients and those who have severe comorbid illness such as CAD require >9 g/dL
Patients with active bleeding and hypovolemia may require a blood transfusion deposits apparently normal hemoglobin
Obtain iron studies before transfusion because after they are inaccurate
Diagnostic options for lower GI bleed
Radionuclide imagine
CT angiography
Angiography
Colonoscopy
Colonoscopy advantages
Precise diagnosis and localization regardless of active bleeding or type of lesion
Endoscopic therapy is possible
Disadvantage colonoscopy
Need colon prep
Risk of sedation in acutely bleeding
Definite bleeding source infrequently identified
Complications of UC
Toxic megacolon
Primary sclerosing cholangitis
Ankylosis spondylitis
Pyoderma gangrenosum
Crohn risks
Fistula
Fissures
Pigmented gallstone formation
Malabsorption
Kidney stones
Complication both crohn and UC
Colon cancer
DVT
Cullen sign
Peri umbilical retroperitoneal hemorrhage
Great turner
Flank retroperitoneal hemorrhage
When start screening for CRC
45-75
76-85
The decision to be screened should be based on a. Persons preferences, life expectancy, overall health, and prior screening history
People over 85
No longer get
Abover average risk of CRC
First degree relative diagnosed under 60 or two first degree at any age
-give colonoscopy every 5 years beginning at 40 or 10 years before age of the youngest affected relative
First degree relative with colorectal cancer or adenomas diagnosed at age over 60 or two second degree relatives with colorectal cancer
Recommended screeningL same options as average risk but begin at age 40
Familial adenomatous polyposis
Recommended screeningL refer for genetic testing or annual screening by sigmoidoscopy, beginning at age 10-12 years
Hereditary nonpolyposis colorectal cancer
Recommended screening: refer to genetic testing, or colonscopy every 1-2 years beginning at age 20-25 years; or 10 years younger than youngest age of colorectal cancer diagnosis in family
CRC screening options
GFOBT
FIT
FIT-DNA
Colonoscopy
CT colonography
Flexible sigmoidoscopy
Flexible sigmoidoscopy with FIT
GFOBT FIT, FIT0DNA
Stool based tests
Colonoscopy, CT colonography, flexible sigmoidoscopy , flexible sigmoidoscopy with FIT
Direct visualization tests
Gold standard CRC screening
Colonoscopy
UC
Mucosal
Colon only
Continuous lesions
PANCA positive, ASCA usually negative
Bloody diarrhea very common
Crypt abscess on histology
Toxic megacolon
Ulcerated pseudopolyps
Smoking protective
Crohns
Transmural
Anywhere along GI tract
Skip lesions
ASCA positive, ANCA negative
Non caseating granuloma on histology
Strictures, obstruction, abscess, weight loss, fistula, perianal disease, fissure
Aphthous ulcers intervening with normal mucosa ,linear fissure cobble stoning, thickened bowel wall, creeping fat
Smoking worsen
DVT prophylaxis
Sequential compression stockings/devices
TED hose
Anticoagulation
Early ambulatory
Before starting an immunomodulatory or biological medication, what should be checked
TPMT enzyme activity (before azathiopurine)
PPD skin test or quantification gold check for TB
Viral hepatitis serology
Abdominal exam
Press firmly on aorta
Risk for AAA
Over 65 smoking male relative with AAA repair
Periumbilical or upper ab mass with expansive pulsation that is 3 cm or more
AAA
Screening by palpating followed by __ decreases mortality
US
Of AAA
US
SL IV
Saline lock, not hooked up to any infusion, flushed with saline and then lockers
HL
Heparin lock, not hooked up to any infusion, flushed with heparin and then locked
KVO
Keep vein open, hooked up to infusion at a slow rate
IVF at NA 125 cc/hr
Maintenance
IVF at NS 1 liter bolus (wide open, need rapid re hydration)
Ok
Jehovah’s Witness
No transfusion
Upper GI sympathetic
T5-T9
Greater splanchnic ,celiac ganglion
Upper GI parasympathetics
Vagus
Occipitomastoid, C1, C2
Lower GI
T10-T11
Lesser splanchnic n, superior mesenteric ganglion
Parasympathetic lower GI
Vagus occiput C1 C2
Lower GI past 1/3 transvers sympathetic
TT12-L2
Least splanchnic n, inferior mesenteric ganglion
Lower GI parasympathetic
S2-4
Pelvic splanchnic
Treat UC
Rebalance Autonomics
Normalize sympathetic
ME, ST< MFR< HVLA< rib raising, paraspinal inhibition in thoracolumar region
Collateral ganglion inhibiton
-superior and inferior mesenteric ganglia relevant regions for UC
Normalize parasympathetic
Vagus-AA/OA,
ME:
St/MFR, stills, HVLE, BLT, suboccipital release, V spread
Pelvic splanchnic nerves
Sacral : ME, SI gap
Sacral inhibition: decreases parasympathetic tone
Sacral rocking: increases parasympthetic tone
Lymphatics
Congestion of lymphatics in bowel channels worsen UC
What is chapman
Non radiating, tender, peas sized ganglion contractions due to lymphatic stasis