PBL: MI Flashcards
1
Q
Heparin
MOA
A
catalyst for binding
antithrombin III + thrombin/Factor Xa
=> neutralization
2
Q
Aspirin
MOA
A
irreversibly binds COX-1 on platelets
prevents platelet aggregation
3
Q
Clopidogrel
MOA
A
ADP receptor antagonist
4
Q
Nitroglycerin
MOA
A
G-protein second messenger
vasodilation, esp. on venous side
decrease preload
5
Q
Morphine MOA
A
mu receptors
6
Q
Mode of inheritance
Familial Hypercholesterolemia
A
autosomal codominant
7
Q
Familial hypercholesterolemia
possible mutations
A
low-density lipoprotein receptor (LDLR)
apolipoprotein B (APOB)
pro-protein convertase subtilisin-kexin 9
8
Q
A