CV Development--Arlen Flashcards

1
Q

The heart tissue develops from what mesoderm?

A

splanchnic mesoderm

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2
Q

How does the heart become innervated embryologically?

A

migration of neural crest cells

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3
Q

What chromosome abnormality is involved in neural crest cell migration into the heart?

A

22q11

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4
Q

Sensory and motor fibers (sympathetic and parasympathetic) are derived from what vertebral region?

A

cervical region

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5
Q

Clinical signifigance of innervation coming from cervical plexus to heart

A

referred pain, angina

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6
Q

Vitelline veins drain

A

GI system

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7
Q

Umbilical vein(s) drain

A

placenta

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8
Q

Cardinal veins give rise to

A

caval system (superior and inferior)

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9
Q

Why are the ventricles in gross lab on the anterior side?

A

folding of arterial end of primative heart anteriorly

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10
Q

Dextrocardia

A

heart rotates in wrong direction

apex of heart pointing to right side

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11
Q

Dextrocardia with situs inversus

A

heart points to right

intestine and GI tract move to opposite sides as well

better survival than dextrocardia without situs inversus

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12
Q

What is the primary role of the endocardial cushions?

A

separate heart into right and left AV canals

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13
Q

Bulbar and truncal ridge tissue is derived from…

A

neural crest mesenchyme

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14
Q

Bulbar and truncal ridge tissue gives rise to…

A

aorticopulmonary septum

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15
Q

How do you get partitioning of bulbus cordis and trucus arteriosis?

A

spiraling forms pulmonary arteries and aorta

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16
Q

Muscular portion of ventricles is formed from these cells

A

myoblasts

17
Q

What forms the interventricular septum (membranous portion)?

A

endocardial cusion

aorticopulmonary septum

18
Q

Which aortic arch forms the aortic arch?

A

left 4th

right 4th is a distractor

19
Q

Proximal portion of left pulmonary artery is derived from which aortic arch?

A

proximal left 6th aortic arch

20
Q

Ductus arteriosis is derived from which aortic arch?

A

distal portion of left 6th aortic arch

21
Q

The ductus arteriosis becomes what structure?

A

ligamentum arteriosum

22
Q

What does the ductus arteriosis connect?

A

aorta and pulmonary artery

ductus = duct

arteriosis = between the major arteries

23
Q

Umbilical veins become what postnatal structure?

A

round ligament