CV Development--Arlen Flashcards
The heart tissue develops from what mesoderm?
splanchnic mesoderm
How does the heart become innervated embryologically?
migration of neural crest cells
What chromosome abnormality is involved in neural crest cell migration into the heart?
22q11
Sensory and motor fibers (sympathetic and parasympathetic) are derived from what vertebral region?
cervical region
Clinical signifigance of innervation coming from cervical plexus to heart
referred pain, angina
Vitelline veins drain
GI system
Umbilical vein(s) drain
placenta
Cardinal veins give rise to
caval system (superior and inferior)
Why are the ventricles in gross lab on the anterior side?
folding of arterial end of primative heart anteriorly
Dextrocardia
heart rotates in wrong direction
apex of heart pointing to right side
Dextrocardia with situs inversus
heart points to right
intestine and GI tract move to opposite sides as well
better survival than dextrocardia without situs inversus
What is the primary role of the endocardial cushions?
separate heart into right and left AV canals
Bulbar and truncal ridge tissue is derived from…
neural crest mesenchyme
Bulbar and truncal ridge tissue gives rise to…
aorticopulmonary septum
How do you get partitioning of bulbus cordis and trucus arteriosis?
spiraling forms pulmonary arteries and aorta
Muscular portion of ventricles is formed from these cells
myoblasts
What forms the interventricular septum (membranous portion)?
endocardial cusion
aorticopulmonary septum
Which aortic arch forms the aortic arch?
left 4th
right 4th is a distractor
Proximal portion of left pulmonary artery is derived from which aortic arch?
proximal left 6th aortic arch
Ductus arteriosis is derived from which aortic arch?
distal portion of left 6th aortic arch
The ductus arteriosis becomes what structure?
ligamentum arteriosum
What does the ductus arteriosis connect?
aorta and pulmonary artery
ductus = duct
arteriosis = between the major arteries
Umbilical veins become what postnatal structure?
round ligament
