PBL Metabolit Sekunder Cendawan Mikro Flashcards

1
Q

Cendawan penghasil pigmen

A

Penicillium sp.

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2
Q

Tipe fungi penghasil pigmen
1. Aspergillus niger
2. Fusarium sp.
3. Monascus sp.
4. Penicillum sp.

A
  1. Hitam > aspergillin > antimikrob
  2. Kuning > benzoquinone > agen antikanker
  3. kuning oren merah > monascorubamine > antioksidan, perwarna makanan
  4. Kuning, merah pink, oren > beta karoten > pewarna tekstil
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3
Q

Penicillium sp. termasuk jamur (1) mekanisme pembuatan beta karoten (2)

A
  1. Aerobik
  2. GPP > FPP > GGPP > phytoene > Lycopene > gama caroten > beta caroten
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4
Q

Pewarnaan kain
1. Ekstrak pigmen
2. Poroses mordanting
3. Proses pewarnaan
4. Larutan mordant yang baik
5. Kain yang baik

A
  1. Pigmen diesktrak dari media menggunakan etanol, media cair
  2. Menyiapan kain direbus dengan larutan mordant agar lebih bisa menyerap warna
  3. Proses pengikatan pigmen pada kain
  4. Besi sulfat lebih baik daripada tawas
  5. Sutra lebih baik dari katun
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5
Q
  1. Siklosprorin A(CsA) dihasilkan oleh
  2. Bentuk berupa
A
  1. Tolypociadium inflatum
  2. Peptida siklik termetilasi
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6
Q
  1. Mekanisme biosintesis BMT menggunakan jalur
  2. Biosintesis siklosporin A dibantu oleh enzim … dengan modul khusus
  3. Tugas nodul C, A, T
A
  1. PKS
  2. NRPS SIMA, modul NM
  3. C= lem, A= diikat, T=menempelkan
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7
Q
  1. Pengujian siklosporin A dilakukan pada
  2. CsA berperan dalam
A
  1. Serangga, larva instar terakhir ( Galleria sp.)
  2. Infeksi jamur pada inang serangga
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8
Q

Manfaat CsA bagi manusia

A
  1. Immunosupressan
  2. Autoimun drugs
  3. Atopic dermatitis medicine
  4. Uveitis medicine
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9
Q

Ciri-ciri Aspergillus terreus

A
  • Berfilamen saprofit
  • termofilik
  • menghasilkan lovastatin
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10
Q
  1. Apa itu lovastatin
  2. Biosintesis lovastatin
A
  1. Golongan statin digunakan untuk menurunkan kadar kolesterol dalam darah
  2. Melalui poliketida = 9 Acatates + 1 met + CoA, ATP, NADPH > Dihydromonacolin L> P450 > manacolin L > monacolin J > lovastatin
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11
Q

Manfaat lovastatin bagi
1. Cendawan
2. Manusia

A
  1. Pertahanan, regulasi pertumbuhan, interaksi
  2. Menurunkan kolesterol, mencegah penyakit kardiovaskular, mencegah penumpukan plak di pembuluh darah
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12
Q

Aplikasi lovastatin

A

Antiperkolesterolemia
Alzheimer
Parkinson
Pengobatan kanker

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