PB#105: Bariatric Surgery and Pregnancy Flashcards
Prevalence of obesity in pregnancy
10-36%
Prevalence of obesity among all reproductive-aged women; prevalence of obesity among reproductive-aged Mexican-American pts; prevalence of obesity among reproductive-aged Black pts
29%; 36%; 50%
Effects of obesity on fertility (2)
Reduced fertility, less likely to respond to ovulation induction (even w/ high-dose gonadotropins)
Primary mechanism for reduced fertility 2/2 obesity
Oligo-ovulation/anovulation
Maternal pregnancy risks associated w/ obesity (13)
GDM, pre-E, C/S, infectious morbidity, operative morbidity/postop recovery complications, prolonged op times, increased blood loss, VTE, unsuccessful VTOLAC, iatrogenic PTD, need for IOL/AOL, higher doses of oxytocin, longer labor course
Effects of obesity on iatrogenic vs spontaneous PTD
Iatrogenic PTD higher in obese pts, spontaneous PTL/PTD lower in obese pts
Fetal/Neonatal risks associated w/ obesity in pregnancy (5)
Congenital anomalies, growth abnormalities, sAB, IUFD, subsequent childhood obesity
Most common congenital anomalies associated w/ obesity in pregnancy (3)
ONTDs, cardiac anomalies, facial clefting
RR of IUFD in obese pts compared to normal weight pts
2.1–4.3-fold greater
Effect of increasing BMI on OB US
Worsening visualization of congenital anomalies, though no effect on EFW calculations
Nonsurgical weight loss approaches (4)
Behavioral changes, diet, exercise, pharmacotherapy
Candidates for bariatric surgery
Pts w/ BMI >40, or pts w/ BMI >35 and other comorbidities
Most effective therapy for morbid obesity
Bariatric surgery
Two general approaches to bariatric surgery
Restrictive, restrictive-malabsorptive combo
Two common bariatric surgeries currently in use, and classification of each one
Roux-en-Y (restrictive-malabsorptive combo), adjustable gastric banding (restrictive)
Pathophysiology of Roux-en-Y procedure
Creates a roux (straight) limb connected to gastric pouch and Y-portion downstream as enteroenterostomy, w/ proximal stomach separate from remaining part of stomach w/ staples
Pathophysiology of gastric banding
Fluid-filled band is placed around stomach near fundus, reducing functional stomach volume
Surgically route of roux-en-Y and of gastric banding
Both can be performed laparoscopically or open
Less common bariatric procedures, and classification of each one (2)
Vertical banded gastroplasty (restrictive), biliopancreatic diversion (malabsorptive)
Effects of weight loss following bariatric surgery on fertility (4)
Improvement in PCOS, improvement in anovulation, improvement in irregular menses, improvement in fertility rates
Risk associated w/ contraception following malabsorptive surgery
Possibility of decreased absorption of OCPs
Most effective intervention to improve medical comorbidities associated w/ obesity (outside of pregnancy)
Weight loss
Percentage of pregnant pts that are still obese after bariatric surgery
80%