Pathoma- Joints

Question 1

What are osteophytes?

Answer 1

reactive bony outgrowths

Question 2

Where do osteophytes usually grow?

Answer 2

in the DIPs (Heberden’s Nodes) and PIPs (Bouchard’s Nodes)

Question 3

What is a pannus?

Answer 3

inflamed granulation tissue

Question 4

What is inflamed granulation tissue called?

Answer 4

a pannus

Question 5

What is the lining of the joint capsule called?

Answer 5

the synovium

Question 6

What is synovium?

Answer 6

lining of the joint capsule

Question 7

What is in granulation tissue?

Answer 7

1. fibroblasts
2. BVs
3. myofibroblasts (contractile)

Question 8

Pleura effusions, LAD, and interstitial lung fibrosis are common in ____.

Answer 8

RA

Question 9

Describe the RA antibody.

Answer 9

IgM autoantibody against the Fc portion of IgG called RF

Question 10

This is an IgM autoantibody against the Fc portion of IgG.

Answer 10

RF (Rheumatoid Factor)

Question 11

What is uveitis?

Answer 11

redness of the eye that can lead to blindness

Question 12

What is Reiter syndrome?

Answer 12

can’t see, can’t pee, can’t climb a tree

Question 13

What is psoriatic arthritis?

Answer 13

axial and peripheral joints involved with sausage digits

Question 14

What causes inflammation in acute gout?

Answer 14

the crystals activate neutrophils

Question 15

What are tophi?

Answer 15

white, chalky aggregates of UA crystals surrounded by fibrosis in soft tissue or joints