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Musculoskeletal > Pathoma - Bone Tumors > Flashcards

Pathoma - Bone Tumors Flashcards

1
Q

Osteoma- location

A

facial bones

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2
Q

Osteoma- association

A

Gardner syndrome (FAP subtype)

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3
Q

Osteoid osteoma - location

A 
long bones (cortex and diaphysis)
benign tumor of osteoblasts
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4
Q

Osteoid osteoma - clinical presentation

A

bone pain that RESOLVES with aspirin

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5
Q

Osteoid osteoma - x-ray

A

bony mass (rim) w/ radiolucent osteoid core

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6
Q

Osteoblastoma - clinical presentation

A

like osteoid osteoma, but larger (>2cm) and pain DOES NOT resolve w/ aspirin

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7
Q

Osteochondroma - location

A

lateral projection of growth plate w/ cartilage cap

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8
Q

Osteochondroma - complications

A

can progress to chondrosarcoma

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9
Q

Osteosarcoma - cause

A

malignant proliferation of osteoblasts

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10
Q

Osteosarcoma - location

A

distal femur or proximal tibia (metaphysis)

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11
Q

Osteosarcoma - populations

A

teens or elderly

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12
Q

Osteosarcoma - associated with

A

retinoblastoma, Paget’s Dz, radiation exposure

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13
Q

Osteosarcoma - biopsy

A

large pleiomorphic cells producing osteoid

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14
Q

Giant Cell Tumor - location

A

epiphysis of long bones

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15
Q

Giant Cell Tumor - x-ray

A

“soap bubble” appearance

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16
Q

Ewing Sarcoma - cell type

A

poorly differentiated neural ectoderm cells

17
Q

Ewing Sarcoma - location

A

diaphysis of long bones

18
Q

Ewing Sarcoma - population

A

Boys <15

19
Q

Ewing Sarcoma - associated translocation

A

t(11:22)

20
Q

Ewing Sarcoma - x-ray

A

“Onion skin” appearance

21
Q

Chondroma - location

A

medulla of hand/foot bones

22
Q

Chondrosarcoma - location

A

medulla of pelvis or central skeleton

23
Q

Metastatic tumors - appearance

A

osteolytic (punched out) lesions

exception: prostate (osteoblastic lesions)

24
Q

Metastatic tumors - most common sources

A

Breast, Lung, Prostate

25
Q

Most common benign tumor

A

osteochondroma

26
Q

Osteochondroma - population

A

males <25

Musculoskeletal (8 decks)

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