Pathology- Oncogenic Viruses

Question 1

HTLV CAUSES ?

Answer 1

ADULT T CELL LEUKEMIA

In JAPAN, CARRIBEAN, AFRICA AND AMERICA

Question 2

HPV CAUSES?

Answer 2

HUMAN PAPILOMA VIRUS - CERVIX (16,18,31,33)

Genital warts - 6&11
Bening warts - 1,2,4,7

Question 3

EBV CAUSSS ?

Answer 3

BURKITT LYMPHOMA (8:14)
Hodgkins lymphoma
NASO PHARYNGEAL AND GASTRIC

Question 4

Hepatitis B&C?

Answer 4

HEPATOCELLULAR CARCINOMA
IMMUNE MEDIATED CHRONIC INFLAMMATION

Question 5

Human gammahepesvirus 8?

Answer 5

HIV
KAPOSI’S CARCINOMA

Question 6

What is chachexia.?

Answer 6

Loss of body fat and muscle
TNF-APLHA & IL-1

Question 7

What is paraneoplasm?

Answer 7

Signs and symptoms in cancer patients that cannot be explained by tumour spread or native tissue harmones production.

Leads to new separate disease

Question 8

What are the 3 paraneoplasm syndromes?

Answer 8

Hypercalcemia
Cushing syndrome
CARCINOID SYNDROME

Question 9

Hypercalcemia ?

Answer 9

PTH harmones in lung breast and ovary

Question 10

Cushing syndrome ?

Answer 10

Excess ACTH LEADS TO INCREASES CORTISOL

MOON FACE
WOMAN WITH A BEARD AND A LUMP
ABDOMINAL STRIAE

Question 11

Carcinoid syndrome ?

Answer 11

Secretion of seratonin
In urine
Liver cancer