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LU4 HS 202 E1 > Pathology of Viral Infections > Flashcards

Pathology of Viral Infections Flashcards

1
Q

[Incubation Period] Dengue

A

3-14 days (ave 4-7)

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2
Q

[Diagnosis] Dengue

A

isolating the virus, detecting viral antigen or RNA in serum or tissues, or detecting specific antibodies in the patient’s serum

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3
Q

[Symptoms] Dengue

A

acute onset of fever accompanied by frontal headache,
retro-orbital pain, body aches, nausea and vomiting,
joint pains, weakness, and rash.

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4
Q

What disease is caused by Rhinovirus?

A

Respiratory Diseases

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5
Q

[Incubation Period] Rhinovirus

A

1-2 Days

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6
Q

[Diagnosis] Rhinovirus infection

A

culture from washings or nasal

secretions

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7
Q

[Symptoms] Rhinovirus infection

A

rhinorrhea, sneezing, and nasal congestion,may have sore throat,

but mild or absent constitutional s/s like body malaise and headache; fever unusual

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8
Q

[Clinical Management] Rhinovirus infection

A

not necessary, since self-limited

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9
Q

[Incubation Period]

Respiratory Syncytial Virus Pneumovirus

A

4-6 days

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10
Q

[Diagnosis]Respiratory Syncytial Virus Pneumovirus

A

isolation of RSV from respiratory secretions,
including sputum, throat swab, and nasopharyngeal
washes

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11
Q

[Symptoms] Respiratory Syncytial Virus Pneumovirus

A

begins with rhinorrhea, low grade fever, cough and

wheezing, mild systemic symptoms

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12
Q

[Management] Respiratory Syncytial Virus Pneumovirus

A

respiratory therapy, including hydration, suctioning of

secretions, administration of humidified O2, antibronchospastic agents, even ventilatory assistance

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13
Q

[Symptoms] Mumps

A

Parotitis, orchitis, encephalitis

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14
Q

[Viral Agent] Measles

A

Rubeola virus

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15
Q

[Diagnosis] Measles

A

mononuclear cell infiltration and multinucleate giant cells.xlymphoid hyperplasia prominent in cervical and
mesenteric lymph nodes, spleen appendix

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16
Q

[Disease] rash – blotchy, reddish-brown – produced by dilatedskin vessels, edema, and a moderate, nonspecific, mononuclear perivascular infiltrate (a vasculitis of small blood vessels)

A

Measles

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17
Q

[Prodromal Period] Rabies

A

2-10 days

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18
Q

[Disease] transient viremia and fever, spinal or brainstem bulbar

A

Polio

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19
Q

[Disease] characterized by rash, arthralgias, and transient interruption in erythrocyte production

A

Parvovirus B19

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20
Q

[Disease] general malaise, chills, fever, headache S/s of CNS dysfunction like anxiety, agitation, paralysis, episodes of delirium, “furious” and “dumb”

A

Rabies

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21
Q

[Clinical Management] Polio

A

anti-virus antibodies control the disease in most cases, vaccine

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22
Q

[Incubation period] Parvovirus

A

4-14 days

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23
Q

[Incubation Period] Small Pox

A

12-14 days

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24
Q

[Incubation Period] Hand, Foot and Mouth Disease

A

4-7 days

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25
Q

Dengue Virus

a. Flaviviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

A

26
Q

HPV

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

D

27
Q

Rhinovirus

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

A

28
Q

Coxsackie Virus

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

A

29
Q

Rabies

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

C

30
Q

Mumps Virus

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

E

31
Q

Respiratory Syncitial Virus/Pneumovirus

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

E

32
Q

[Duration]

Dengue acute febrile period

A

2-10 days; negative serology; still mounting antibody response

33
Q

Platelet count in DHF

A

100,000/mm3, note normal: 150,000/mm3

34
Q

[Identify]

Small, non-enveloped ssRNA, acid labile and grows best at 33-34degC

A

Rhinovirus

35
Q

Which antibody is protective against Respiratory syncitial virus?

A

Nasal IgA neutralizing antibody

36
Q

ssRNA enveloped Paramyxiviridae with large surface glycoprotein with both hemagglutinin and neuraminidase activity

A

Mumps virus

37
Q

[Viral pathogen]

German measles

A

Rubella

38
Q

[Viral pathogen]

Chicken pox, shingles

A

Varicella, varicella-zoster

39
Q

Rubella

a. Picornaviridae
b. Parvoviridae
c. Lyssaviridae
d. Papovavridae
e. Paramyxoviridae

A

E

40
Q

Protection against Rubella is via

a. cell mediated immunity
b. antibody mediated immunity

A

B

41
Q

ulcerated mucosal lesions in the oral cavity near the opening of the stensen’s duct

A

Koplik spots

42
Q

Measles giant cells a.k.a

A

Warthin-Finkeldey cells

43
Q

Round eosinophilic cytoplasmic

inclusions measuring 1-7 μm are pathognomonic of rabies

A

negri bodies

44
Q

What is the preferential site for negri body formation

A

hippocampal neurons

45
Q

Polio __ attenuated vaccine can in some cases

revert back to wild type (most pathogenic)

A

Polio 3 attenuated vaccine can in some cases

revert back to wild type (most pathogenic)

46
Q

Which Polio strain is most virulent?

A

Polio1

47
Q

killed, formalin-fixed polio vaccine

a. Sabin
b. Salk

A

B

48
Q

live, attnuated polio vaccine

a. Sabin
b. Salk

A

A

49
Q

which polio vaccine is less immunogenic?

a. Sabin
b. Salk

A

B

50
Q

Neuronophagia is a typical manifestation of

a. rabies
b. polio
c. Herpes
d. Chicken pox

A

B

51
Q 
The ff are sexually transmitted except
a. HPV 16, 18
b. Molluscum contangiosum
c. Herpes
d. HIV
e. AOTA
F. NOTA
A

F

52
Q

[Viral pathogen]

Infectious mononucleosis

A

Epstein Barr Virus

53
Q

[Viral Pathogen]

Kaposi Sarcoma

A

Herpes Simplex 8

54
Q

[Disease that it causes]

HPV Types 6,10, 11, 40-45

A

anogenital warts/ condyloma acuminata

55
Q

[Disease that it causes]

HPV Types 16, 18, 31

A

squamous cell dysplacias and squamous cell carcinomas of the female genital tract;
16,18 most common
16 most common in the Philippines

56
Q

Cytopathic effect of HPV infected cells;when squamous cells become large with shrunken nuclei enveloped in large cytoplasmic vacuoles

A

Koilocytosis

57
Q

verrucae vulgares a.k.a

A

common warts

58
Q

verrucae planae a.k.a

A

flat warts

59
Q

condyloma acuminata a.k.a

A

anogenital warts

60
Q

papular lesions located on the folds of moist intertriginous areas that coalesce to form flat, wartlike lesions, especially around the genitalia and anuslesions associated with secondary syphilis

A

condyloma lata

LU4 HS 202 E1 (6 decks)

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