Pathology of the Breast

Question 1

what is the pathology of fibroadenoma?

Answer 1

> proliferation of the stroma and epithelium

> ducts are distorted and elongated leading to pericaralicular growth and slit like structures

Question 2

in what age group are fibroadenomas most common?

Answer 2

> adolescents

> young adults (3rd decade)

Question 3

what is the presentation of a fibroadenoma?

Answer 3

> freely mobile
well circumcised
not painful

Question 4

what is the presentation of a tubular adenoma?

Answer 4

discrete freely movable mass

Question 5

what is the presentation of lactating adenoma?

Answer 5

enlarged mass in lactation and pregnancy

Question 6

what is intraduct papilloma?

Answer 6

epithelial hyperplasia

Question 7

how does an intraduct papilloma present?

Answer 7

nipple discharge in middle aged women

Question 8

what is the pathology of fat necrosis?

Answer 8

> fibrosis
calcification
liquid filled cysts
ltistiocytes (plus foamy cytoplasm)

Question 9

how does fat necrosis present?

Answer 9

> egg shell on mammography
antecedent trauma
prior surgical intervention

Question 10

what is the pathology of phyllodes tumour?

Answer 10

> cysts on cut surface
> fleshy leaf like pattern
> circumcised
> connective tissue and epithelial elements
> haematogenous metastasis

Question 11

what is pagets disease a result of?

Answer 11

intraepithelial spread of intraductal carcinoma

Question 12

how does pagets disease present?

Answer 12

> pain
> itching
> scaling
> redness
> ulceration
> crusting
> serous or bloody discharge

Question 13

what is gynecomastia in men associated with?

Answer 13

> cirrhosis of the liver
> hyperthyroidism
> chronic renal failure
> chronic pulmonary disease
> hypogonadism
> hormone use