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GI > Pathology of Colon 2 - Neoplasia > Flashcards

Pathology of Colon 2 - Neoplasia Flashcards

1
Q

How does dysplasia tend to appear in the colon?

A

The presence of polyps

Can mark the beginning of progression to colon cancer

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2
Q

Types of adenomatous polyps?

A

Tubular
Villous
Tubulovillous

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3
Q

Describe low grade dysplasia

A

Increased nuclear numbers & size

Reduced mucin

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4
Q

Describe high grade dysplasia

A

Carcinoma in situ (growth is in the cells normal place)

Crowded
Very irregular arrangement
Not yet invasive

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5
Q

Commonest form of colorectal carcinoma?

A

Adenocarcinoma (98%)

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6
Q

Risk factors for colorectal carcinoma?

A 
Smoking 
Lifestyle 
Family history 
IBD (CD & UC)
Genetics
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7
Q

Describe symptoms & characteristics of right sided colorectal carcinomas

A

Weight Loss
Anaemia
Polyploid growth

Vague pain
Weakness
Obstruction common

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8
Q

Describe left sided colorectal adenocarcinomas

A 
Annular shape/growth
Often cause bleeding 
Altered bowel habit (diarrhoea)
Obstruction common
Tenesmus
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GI (46 decks)

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