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RUSVM Pathology II > Pathology II Lab Exam Material > Flashcards

Pathology II Lab Exam Material Flashcards

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1
Q

14 year old cat. MDx?

A

Bilateral thyroid nodular hyperplasia or bilateral thyroid adenomas

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2
Q

Icterus is noted in the ocular mucous membranes of this pig with massive hepatic necrosis. Name the disease. What is the cause?

A

Hepatosis dietetica

Caused by Vitamin E/Se deficiency

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3
Q

Heart from a dog.

MDx? Name the endocrine abnormality this condition is typically associated with:

A

Coronary Atherosclerosis

Associated with hypothyroidism (due to chronic hypercholesterolemia associated with hypothyroidism)

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3
Q

Lungs from a newborn calf found dead in the pasture.

MDx?

A

Diffuse pulmonary atelectasis

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4
Q

What is the required formalin to tissue ratio for fixation of tissue?

A

10:1

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4
Q

Lungs from a young horse. Etiology?

A

Rhodococcus equi

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5
Q

Adrenal glands. MDx?

A

Adrenal cortical hyperplasia

Caused by ACTH-secreting pituitary adenoma. ACTH overstimulates the cortex of the adrenal gland and results in hyperplasia

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6
Q

The picture shows multifocal hepatitis in a pig condemned at slaughter. What is the most likely parasitic cause?

A

Ascaris suum

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7
Q

What is your top differential for this neoplastic condition in a cat?

A

lymphosarcoma

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8
Q

Note the rib impressions. This dog also had renal disease.

What’s going on here?

A

Uremic pneumonitis

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8
Q

Observe the dilation of the renal pelvis and ulceration/necrosis at the renal papilla. What is this condition called?

A

Pyelonephritis

Inflammation of the renal pelvis and renal parenchyma

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9
Q

This ‘tiger heart’ appearance is a result of what disease?

A

Foot and Mouth Disease (FMD)

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9
Q

Tissue from a pig.

Etiology?

A

Actinobacillus pleuropneumoniae

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11
Q

What is the name of this disease in a pig?

What is it caused by?

A

Name of disease: Hepatosis dietetica

Cause: Vitamin E/Se deficiency

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12
Q

MDx for this kidney from an FIP-positive cat?

A

Multifocal pyogranulomatous nephritis

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13
Q

Identify the abnormality.

A

Rectovaginal fistula

The vulva functions as a common opening to the urogenital and GI tracts. This is usually associated with Atresia Ani.

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13
Q

Intestines from a young sow with profuse hemorrhagic diarrhea caused by Lawsonia inracellularis. MDx?

A

Proliferative hemorrhagic enteropathy

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14
Q

Identify this non-inflammatory condition due to deposition of glycosaminoglycans with fibrinoid degeneration of connective tissue, most common in the left atria and proximal aorta:

A

Mucoarteritis/endocarditis

Commonly associated with uremia

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15
Q

Lungs from a foal with a history of respiratory disease poorly-responsive to antibiotic therapy.

MDx? EDx?

A
  • MDx: Multifocal pyogranulomatous pneumonia
  • EDx: Rhodococcal pneumonia
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16
Q

MDx?

A

chronic pancreatic necrosis

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16
Q

Intestine from a grower pig. Etiology? EDx?

A
  • Etiology: Lawsonia intracellularis
  • EDx: Lawsonial enteritis
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16
Q

Which bacterial organism is this necrotic enteritis associated with in a pig?

A

Lawsonia inracellularis

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17
Q

Identify the abnormality in the picture:

A

Osteosarcoma induced by Spirocerca lupi

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18
Q

Pig. Name of disease? Etiology?

A
  • Name of disease: Atrophic Rhinitis
  • Etiology: Pasteurella multocida (A and D) and Bordetella bronchiseptica
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18
Identify this abnormality in the horse associated with ingestion of Blister Beetles in alfalfa hay
**ulcerative gastritis** Blister beetles in alfalfa hay - ***Cantharidin toxicity***
20
This tissue is from a dog with kidney disease. MDx?
**Hemorrhagic ulcerative gastritis**
21
What abnormality are we looking at here? What is a common cause of this abnormality?
**Arthrogyposis,** likely as a result of **BVD** ## Footnote ***\*\*Schmallenberg Virus** would be a good differential if you're in the UK*
22
Tissue from an adult cat. MDx?
**parathyroid hyperplasia**
23
The hindlimb enlargement in this green iguana is due to **fibrous osteodystrophy**. Which endocrine abnormality is this condition associated with?
**Nutritional hyperparathyroidism**
25
Tissue from a cat. MDx?
**Hepatic lipidosis**
25
Which special stain is commonly used to confirm *Lawsonia intracellularis* in a pig?
**Warthin-Starry (silver) stain**
26
MDx for this tissue in a pig?
**Panlobular hepatic necrosis** *The disease is hepatosis dietetica; caused by Vitamin E/Se deficiency*
27
Colon from horse. MDx?
**Chronic segmental ischemic necrosis** *Associated with _Strongylus vulgaris_. The large intestine is supplied by the cranial mesenteric artery, leading to ischemia*
28
The image below is often the cause of death in uremic animals. Identify.
**pulmonary edema** *Pulmonary edema results from damage to the air-blood barrier and plasma fluid leaks into the alveoli*
30
Pictured is **chronic arteritis with intraluminal thrombosis** in a horse. What is the most likely etiology?
***Strongylus vulgaris*** Note the larvae in the tunica intima. EDx: verminous arteritis
31
What is the name of this disease? Etiology?
* **Name of disease:** Jowl abscess * **Etiology:** *Streptococcus porcinus*
33
Sheep. MDx? Cause? Name of Disease?
* **MDx:** Nasal carcinoma or adenocarcinoma * **Cause:** Enzootic Nasal Tumor Virus (ovine betaretrovirus) * **Name of Disease:** Ovine enzootic nasal carcinoma
34
Identify the abnormality in this image:
**Uremic stomatitis/glossitis** *Oral bacteria transform urea into ammonia, which irritates the oral epithelium and causes ulceration of the mucosa**.** Note that the lesions are more on the ventral surface of the tongue. This is pretty characteristic of lesions associated with uremia.*
35
This is the spleen from a Bernese Mountain Dog. What is the most likely differential?
**Histiocytic sarcoma**
36
Top two differentials for this pattern of nephritis in a cat?
**FIP** and **lymphosarcoma** ## Footnote *MDx: multifocal pyogranulomatous nephritis*
37
The extreme dilation of the ventricles and thinning of cerebrocortical tissue shown in the image is characteristic for:
**Congenital hydrocephalus**
39
Liver from a dog. MDx?
**Hepatic cirrhosis**
41
Tissue from a steer. MDx? Etiology?
* **Mdx:** Fibrinous pneumonia * **Etiology**: *Mannheimia haemolytica*
42
What abnormality are we seeing in this cat? What is the most common cause?
**Saddle thrombus** *Most likely cause is _hypertrophic cardiomyopathy (HCM)_ in cats*
43
T/F: **Parathyroid hyperplasia** (pictured) is seen with secondary renal/nutritional hyperparathyroidism and pseudohyperparathyroidism observed in dogs with apocrine gland adenocarcinoma of the anal sac
**False** *Parathyroid hyperplasia is seen with secondary renal/nutritional hyperparathyroidism, but **not** with pseudohyperparathyroidism observed in dogs with apocrine gland adenocarcinoma of the anal sac*
45
Skin from a dog. Dx?
**Calcinosis cutis** Very suspicious for underlying hy**_per_**adrenocorticism
46
Tongue from a cat. MDx? Most likely cause?
**Vesicular glossitis**; calicivirus infection
47
Top differential?
**Renal lymphosarcoma**
48
Tissues from a calf. MDx?
**Chronic suppurative omphalophlebitis** *Fetal umbilical vein should close after birth and become the round ligament from liver to skin. If it gets infected/doesn’t close, it can become markedly thickened and can lead to liver abscesses (Multifocal areas of chronic suppurative abscesses, as seen in the photo)*
50
Secondary disease to uremia. MDx?
**Multifocal intercostal subpleural mineralization** *May be associated with deposition of calcium secondary to cell injury, hypercalcemia, or hyperphosphatemia*
51
Heart from a feedlot steer. MDx?
**Chronic suppurative myocarditis** Likely the result of *Histophilus somni* infection
52
MDx?
**Hemorrhagic and necrotizing pancreatitis** *What the image shows is acute pancreatitis with saponifiction of fat. The fat necrosis is secondary to release of enzymes from the pancreas. These enzymes are proteolytic and can cause fat necrosis.*
53
MDx?
**Embolic pneumonia**
55
Adrenal glands from a horse. MDx?
**Adrenal pheochromocytoma**
55
With which endocrine abnormality is this opacity of the lens fairly common?
**Diabetes**
56
Mouth of a dog. Identify the abnormality.
**Oral melanoma**
57
The **myxedema** shown in this obese dog is most commonly associated with which endocrine abnormality?
**hypothyroidism** MDx for picture below: thyroid atrophy
58
Heart from a 14 year old cat with hy**_per_**thyroidism. MDx?
**biventricular cardiac hypertrophy**
59
What abnormality are we looking at here?
**Cerebellar coning**
60
Cecum of a horse. Woah, what are those?
***Anoplocephala perfoliata***
61
Tissue from a cow with severe chronic diarrhea and emaciation. MDx? Etiology?
* **MDx:** Granulomatous enteritis * **Etiology:** *Mycobacterium avium* subsp. *paratuberculosis*
62
Liver from a cow. What is the most likely etiology?
***Fascioloides magna*** *The black discoloration on the surface and throughout the parenchyma is a result of the iron porphyrin pigment that is very characteristic of F. magna*
63
When preparing a histological specimen, what is the ideal thickness of tissue in the cassette?
**~3 mm**

RUSVM Pathology II (5 decks)

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