pathology II Flashcards
What is conduction aphasia?
Caused by damage to the arcuate fasciculus (connects wernickes and brocas area) - patient can’t repeat what you say
What is global aphasia?
Wernickes, brocas and arcuate fasciculus are all affected
What is transcortical motor aphasia
affected frontal lobe around broca area, but broca is spared
what is transcortical senosry aphasia
affects temporal lobe around wenicke area but wernicke area is spared
what is transcortical mixed aphasia?
broca and wernicke areas and arcuate fasciculus remain intact but surrounding watershed areas are affected
saccular aneurysm aka
berry aneurysm
most common location for a berry aneurysm
junction of Acomm and ACA
how do berry aneurysms prsent
silent until they rupture -> subarachnoid hemorhage
An aneurysm in the Acom may compress surrounding structure resulting in what?
Bitemporal hemianopia (compresses optic chiasm)
An aneurysm in the Pcom may compress surrounding structures resulting in what?
CN III palsy -> mydriasis, down and out eye and ptosis
What presents similarly to a CN III palsy?
Ischemic neuropathy seen in diabetes, however pupil is spared
What are Charcot-Bouchard microaneurysms commonly found?
Small vessels such as lenticulostriate arteries
What are Charcot-Bouchard microaneurysms associated with?
chronic hypertension
What can Charcot-Bouchard microaneurysms result in?
hemorrhagic intraparenchymal strokes
Where do most partial (focal) seizures originate?
medial temporal lobe
Types of partial seizures
simple partial and complex partial
How do simple partial seizures present
consciousness remains, may be motor, sensory, autonomic or psychic
How do complex partial seizures present
impaired consciousness and automatisms
Status epilepticus
continues (>5min) or recurring seizures that may result in brain injury
types of generalized seizures
absence (petit mal) Myoclonic Tonic-clonic (grand mal) Tonic Atonic
What will be seen on a EEG of an absence seizure?
3 Hz spike-and-wave discharges
Atonic seizures are commonly mistaken for…
drop seizures
What is Juvenile Myoclonic epilepsy?
characterized by absence, myoclonic and grand mal seizures. Common in children.
Absence -> myoclonic -> grand mal
Typically myoclonic jerks on awakening from sleep
What is post-ictal state mean?
After a grand-mal seizure, this is a period of brain recovery that presents as confusion/lack of alterness and lasts minutes to hours
Treatment for childhood absence epilepsy
Ethosuxamide
Cause of fever
cytokine activation during inflammation (infection)
Cause of heat stroke
the inability of body to dissipate heat (exertion)
temperature seen in fever
Usually <40 C