PATHOLOGY- ADAPTIVE Flashcards
What is adaptive immunity?
It consists of cell-mediated responses and antibody (humeral responses). CARRIED OUT BY B AND T cells.
What do T cells do?
T cells drive cell-mediated immunity, it involves the activation of macrophages, natural killer cells (NK) and antigen-specific cytotoxic T- lymphocytes. A key feature of the adaptive immune system is immunological memory, whereby each pathogen is “remembered” by a signature T cell receptor, and/or B cell receptor.
What do B cells do?
B Cells produce antibodies and drive humoral immunity. A key feature of the adaptive immune system is immunological memory, whereby each pathogen is “remembered” by a signature T cell receptor, and/or B cell receptor.
What three main molecules are involved in the recognition of foreign antigens?
- Toll-like receptors (Innate).
- B cell receptors (Adaptive).
- Major Histocompatibility complex (MHC).
What does a B cell receptor do?
Multiple genes come together to make things such as mhc proteins and t and b cell receptor. It can pick and choose what genes it wants- wide rnge- diff specific patterns for specificity.