Pathology Flashcards
normal/norm
any tissue or organ functionally intact, free from disorder, and capable of sustaining its function
anomally
deviation from the norm that is non-lethal and does not significantly change function
pathology
deviation from the norm that comprises and restricts function of a tissue/organ
skeletal evidence of disease
- not all diseases will affect the skeleton and not all diseases that can affect the skeleton will do so in all people
- skeletal reactions to disease tend to be generalized
how can disease affect the bone?
- formation
- destruction
- density
- size
- shape
lytic lesions
abnormal destruction of cells
blastic/sclerotic lesions
abnormal growth of cells
periosteal reaction
- formation of new bone in response to injury of or other stimuli to the periosteum surrounding the bone
- can be caused by a tumor, infection, trauma, certain drugs, and some abnormal metabolic conditions
osteomyelitis
- any infection of bone and tissue
- bone may enlarge and form bone buttresses/sheaths, drainage channels for pus, and/or islands of dead bone
- infection that moved to the bone
infectious disease
- may be bacterial, viral, fungal, or parasitic
- bone response is slow
syphilis
- caused by venereal tereponemal infection
- only in the third stage
- affects periosteal new bone
- affects bones closest to the skin, like frontal, nasal aperture, tibia, ribs, and sternum
caries sicca
- syphilis symptoms
- cavities formed and bones try to build around it
saber tibia
- syphilis symptoms
- new bone added to the bone to give it a bowing look
Tuberculosis
- an airborne bacterial disease
- may result in lytic lesions, vertebral collapse, little to zero bone formation near lesions, can spread to other bones
Leprosy
- an airborne bacterial infection
- may result in: concentric loss of bone from phalanges, rhinomaxillary syndrome (upper roof of the mouth and nose wear away)