Pathology Flashcards
1
Q
Acute inflammation - Definition
A
- Initial + transient series of tissue reactions to injury
2. Appendicitis
2
Q
Hyperplasia - definition
A
- Increase in cell number by mitosis
2. Benign prostate hyperplasia
3
Q
Granuloma - Definition
A
- Aggregate of epitheliod histocytes
2. Crohn’s disease
4
Q
Disorders of development of growth - Classification
A
- Congenital = present at birth
- Genetic
a. Inherited = inherited genetic abnormality
(Familial adenomatous polyposis AD)
b. Spontaneous = spontaneous mutation - Non genetic - environmental = acquired by environmental factors (fetal alcohol syndrome)
5
Q
Cells that can regenerate
A
- Hepatocytes
- Pneumocytes
- All blood cells
- Gut/skin epi
- Osteocytes
6
Q
Cells that can’t regenerate
A
- Myocardial cells
2. Neurones
7
Q
Acute inflammation - Outcomes
A
- Resolution (acute lobar pneumonia)
- Suppuration
- Organisation
- Progression to chronic inflammation
8
Q
Malignant tumour
A
- Invasive
- Not all metastatic (basal cell carcinoma)
- Rapid growth - irregular border
- Don’t resemble parent cells
- pleomorphic nuclei (vary shape and size)
9
Q
Adenoma
A
- Benign tumour of glandular/secretory epi
2. Prefix with cell type of origin
10
Q
Screening programmes
A
- Cervical cancer
- Breast cancer
- Colorectal cancer
11
Q
Carcinogen
A
- Environmental agent participating in causation of tumours
- Carcinogenic (malignant)
- Oncogenic (tumour)
- Act on DNA
- Eg asbestos
12
Q
Lipoma
A
Benign tumour of adipocytes
13
Q
Adenocarcinoma
A
- Malignant tumour of glandular epi
2. Coupled w name of tissue of origin
14
Q
Carcinoma
A
- Malignant tumour of epi
2. Prefixed by name of epi cell type
15
Q
Leiomyoma
A
Benign tumour of SM cells