GU Flashcards
Benign prostatic hyperplasia - Treatment
- Relax when voiding and double voiding
- Alpha 1 antagonists (oral tamsulosin) –> relax SM in bladder neck
- 5-alpha-reductase inhibitor (oral finasteride) –> testosterone =/ dihydrotestoserone (less prostatic growth)
- Transurethral resection of prostate
- Transurethral incision of prostate
Polycystic disease Autosomal dominant - Extrarenal presentation
- Berry aneurysm - SAH
- Polycystic liver disease
- Pancreatitis
- Mitral valve prolapse
- Diverticular disease
Bladder cancer - Risk factors
- Smoking
- Occupational exposure to carcinogens
- Schistomiasis (parasite) —> chronic inflammation of urinary tract
- Male
- Family history
Cystitis - Treatment
- Trimethoprim / cefalexin
2. Ciprofloxacin / co-amoxiclav
Renal Cell Carcinoma - Presentation
- Haematuria
- Flank pain
- Abdominal mass
- Invasion of L renal V –> compress L testicular V (varicocele)
- Anaemia (less EPO)
Kidney functions
- Secrete waste/excess
- Synthesis erythropoietin
- Activate 25 hydroxy vit D –> 1,25 dihydroxy vit D
- Control BP
Chronic Kidney disease - Causes
- DM 2>1
- Hypertension
- Glomerulonephritis
- Polycystic Kidney disease
- SLE
Erectile dysfunction - Definition
Inability to gain and maintain an erection long enough to receive sexual satisfaction
Nephrotic Syndrome - Presentation
Triad of
- Proteinuia >3.5g/24hrs
- Hypoalbuminaemia
- Oedema
- Severe hyperlipidaemia –> albumin loss –> liver overdrive –> raised cholesterol
- Frothy urine
Nephrotic Syndrome - Causes
- DM
- RA/SLE
- Amyloid
- Infections
- Malignancy
Storage symptoms
- Urgency
- Nocturia >30% at night
- Freq
- Overflow incontinence
Voiding symptoms
- Poor intermittent stream
- Hesitancy
- Incomplete emptying
- Post micturition dribbling
- Straining
- Haematuria
- Dysuria (pain)
Stress incontinence - Treatment
- Pelvic floor exercises
- Duloxetine
- Sling
- Artificial sphincter
Prostate cancer - Risk factors
- Family history
- Afro-Carribean
- HOXB13 gene
- BRCA2 gene
- Increasing age
Sexually transmitted infections - Aetiology
- Chlamydia trachomatis
(gram -ve) - Neisseria gonorrhoea
(gram -ve diplococci)
Chlamydia - Treatment
- Partner management
- Oral azithromycin stat or oral doxycycline for 7 days
- Preg - Erythromycin for 14 days or azithromycin stat
- Test for other STIs
Gonorrhea - Treatment
- PArtner notification
- Test for other STIs
- IM ceftriaxone w azithromycin stat
Chronic Kidney Disease- Classification
1 - eGFR >90mL/min 2. 60-89 3A 45-59 3B 30-44 4 15-29 5 <15
Renal stones - Composition
- Ca oxalate (C)
- Ca phosphate
- Uric acid
Bladder carcinoma - Presentation
- Painless haematuria
- Recurrent UTIs
- Voiding irritability
Nephritis Syndrome (glomerulonephritis) - Presentation
- Haematuria
- Proteinuria <2g in 24hrs
- Hypertension
- Oedema
- Oliguria
UTI - Definition
> 10^5 organisms/ml of fresh mid-stream urine
UTI - causative organisms
KEEPS K = Klebsiella E = E. coli E = Enterococci P = Proteus S = Staph spp (coagulase -ve)
UTI - Urine dipstick
1. Positive nitrites (nitrates --> nitrites) 2. Leucocyte elastase 3. Positive leucocytes 4. Foul smelling urine 5. Proteinuria