Pathology

Question 1

What’s the difference between clinical and anatomic pathology?

Answer 1

Anatomic involves formerly alive tissue

Clinical pathology is done in a lab

Question 2

Avenzoar

Answer 2

First physician known to have made postmortem dissections

Question 3

Rudolf Virchow

Answer 3

Generally recognized to be the father of microscopic pathology

Question 4

What’s the difference between histology and cytology?

Answer 4

Histology looks more at tissue as an organized unit- still tries to preserve tissue structure
Cytology samples the cells and looks exclusively at type and cellular changes

Question 5

What types of samples can be submitted for cytology and histology?

Answer 5

Cytology- smears
Histology- get parts of organs from an -ectomy
FNA biopsies get sent to cytology
Core bx is sent in formalin to pathology

Question 6

What fixatives are used for histology?

Answer 6

Formalin

Alcohol

Question 7

Well circumscribed

Answer 7

Fibroadenoma

Question 8

Smoothly lobulated

Answer 8

Lipoma

Question 9

Verrucous

Answer 9

Cutaneous condyloma

Question 10

Papillary

Answer 10

Bladder tumors

Question 11

Velvety

Answer 11

Nl gallbladder mucosa

Question 12

Macule

Answer 12

Lentigo

Question 13

Papule

Answer 13

Mole

Question 14

Friable

Answer 14

Necrotic tumors

Question 15

Viscous

Answer 15

Thick

Question 16

Serosanguinous

Answer 16

Serum tinged with blood

Question 17

Serous

Answer 17

Like serum (watery)

Question 18

Mucinous

Answer 18

Thick and sticky or gelatinous

Question 19

Tacky

Answer 19

Sticky

Question 20

Suppurative

Answer 20

Green thick exudate

Question 21

Hematoxylin

Answer 21

Stain for nuclear material

Question 22

Eosin

Answer 22

Stain for cytoplasmic material

Question 23

What does the pathologist do in the operating room?

Answer 23

If there is a surgery that involves multiple steps for the dx or the dx is made intraoperatively and possibly incidentally

Question 24

Ziehl-Neelson

Answer 24

Mycobacteria

Question 25

Congo red

Answer 25

Amyloid

Question 26

Diff quick

Answer 26

Modified Giemsa stain

Question 27

Giemsa

Answer 27

Lymphoproliferative disorders

Question 28

Gram

Answer 28

Bacteria

Question 29

Iron

Answer 29

Bone marrow

Question 30

Mucicarmine

Answer 30

Adenocarcinomas

Question 31

Periodic acid Schiff

Answer 31

Tumors with glycogen

Question 32

Silver stain

Answer 32

Infectious dz

Question 33

Toluidine blue

Answer 33

Mast cell dz

Question 34

Trichrome

Answer 34

Liver

Question 35

Wrights

Answer 35

Blood smears

Question 36

What is the purpose of immunoperoxidase studies?

Answer 36

``` Classification of tumors Prognostic factors Predictive factors to guide specific therapy Identification of extracellular material Identification of infectious agents ```

Question 37

Breast special studies

Answer 37

ER/PR HER2/neu GCDFP-15

Question 38

Carcinoid tumor special studies

Answer 38

Chromogranin

Question 39

Lung adenocarcinoma special study

Answer 39

TTF-1

Question 40

Squamous cell carcinoma special studies

Answer 40

CK5/6 p63 p16 HPV

Question 41

Thyroid special tests

Answer 41

Thyroglobulin

Question 42

Melanoma special test

Answer 42

S100 protein