Pathology Flashcards

1
Q

What’s the difference between clinical and anatomic pathology?

A

Anatomic involves formerly alive tissue

Clinical pathology is done in a lab

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2
Q

Avenzoar

A

First physician known to have made postmortem dissections

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3
Q

Rudolf Virchow

A

Generally recognized to be the father of microscopic pathology

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4
Q

What’s the difference between histology and cytology?

A

Histology looks more at tissue as an organized unit- still tries to preserve tissue structure
Cytology samples the cells and looks exclusively at type and cellular changes

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5
Q

What types of samples can be submitted for cytology and histology?

A

Cytology- smears
Histology- get parts of organs from an -ectomy
FNA biopsies get sent to cytology
Core bx is sent in formalin to pathology

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6
Q

What fixatives are used for histology?

A

Formalin

Alcohol

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7
Q

Well circumscribed

A

Fibroadenoma

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8
Q

Smoothly lobulated

A

Lipoma

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9
Q

Verrucous

A

Cutaneous condyloma

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10
Q

Papillary

A

Bladder tumors

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11
Q

Velvety

A

Nl gallbladder mucosa

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12
Q

Macule

A

Lentigo

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13
Q

Papule

A

Mole

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14
Q

Friable

A

Necrotic tumors

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15
Q

Viscous

A

Thick

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16
Q

Serosanguinous

A

Serum tinged with blood

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17
Q

Serous

A

Like serum (watery)

18
Q

Mucinous

A

Thick and sticky or gelatinous

19
Q

Tacky

A

Sticky

20
Q

Suppurative

A

Green thick exudate

21
Q

Hematoxylin

A

Stain for nuclear material

22
Q

Eosin

A

Stain for cytoplasmic material

23
Q

What does the pathologist do in the operating room?

A

If there is a surgery that involves multiple steps for the dx or the dx is made intraoperatively and possibly incidentally

24
Q

Ziehl-Neelson

A

Mycobacteria

25
Q

Congo red

A

Amyloid

26
Q

Diff quick

A

Modified Giemsa stain

27
Q

Giemsa

A

Lymphoproliferative disorders

28
Q

Gram

A

Bacteria

29
Q

Iron

A

Bone marrow

30
Q

Mucicarmine

A

Adenocarcinomas

31
Q

Periodic acid Schiff

A

Tumors with glycogen

32
Q

Silver stain

A

Infectious dz

33
Q

Toluidine blue

A

Mast cell dz

34
Q

Trichrome

A

Liver

35
Q

Wrights

A

Blood smears

36
Q

What is the purpose of immunoperoxidase studies?

A
Classification of tumors
Prognostic factors
Predictive factors to guide specific therapy
Identification of extracellular material
Identification of infectious agents
37
Q

Breast special studies

A

ER/PR
HER2/neu
GCDFP-15

38
Q

Carcinoid tumor special studies

A

Chromogranin

39
Q

Lung adenocarcinoma special study

A

TTF-1

40
Q

Squamous cell carcinoma special studies

A

CK5/6
p63
p16
HPV

41
Q

Thyroid special tests

A

Thyroglobulin

42
Q

Melanoma special test

A

S100 protein