Chapter 13 Flashcards
What is extremely prevalent?
Hepatic arterial anatomic variation
Where are the liver and gallbladder located?
RUQ
What does bile do?
Produced by the liver and stored in the gallbladder
Critical for the absorption of fats
Function of CCK
Released by the intestine in response to ingested fats
Causes the gallbladder to contract and propel bile through the cystic duct, into the common bile duct, and eventually into the duodenum
Central roles of the liver
Nutrient and drug metabolism
Synthesis of coagulation proteins
Detoxification of the blood
Pathway of the blood supply of the liver in m.ost people
Arterial blood from the aorta reaches hepatobiliary system via the right and left hepatic arteries, which are terminal branches of the proper hepatic artery
Blood supply of the gallbladder
Supplied by the cystic artery, which commonly arises from the right hepatic artery
Cystic artery courses through the triangle of Calot
What is the triangle of Calot composed of?
Inferior border of the liver
Common hepatic duct
Cystic duct
Pathway of replaced or recurrent left hepatic artery
Courses from the left gastric artery through the hepatogastric ligament
Pathway of replaced or recurrent right hepatic artery
When it branches off the SMA, frequently travels to the right of the common bile duct in the lateral hepatoduodenal ligament
Venous blood supply of the liver
70% of its blood supply via the portal vein
How is deoxygenated blood from the liver drained?
Drained by three large intraparenchymal hepatic veins (right, middle, left) that empty in the IVC
Where do veins of the gallbladder penetrate?
Penetrate the hepatic parenchyma in the vicinity of the gallbladder fossa
Morphologic vs functional classification of the liver
Morphologic: Divides liver into four lobes; lobes are separated by external fissures or ligaments
Functional: Divides liver into eight segments that are supplied by distinct branches of the arterial and portal blood supply.
How are segments of the liver separated according to the functional classification?
By the vertically oriented portal scissurae containing the hepatic veins and the transversely oriented portal pedicles containing the portal vein branches within the hepatic parenchyma
In the functional classification of the liver, what constitutes the right hemiliver?
What constitutes the left hemiliver?
Segments 5-8
Segments 2-4
What is the surgeon’s initial priority in evaluating the patient with hepatobiliary dz?
Determine whether pt has necrotic or infected tissue
If biliary obstruction with infection is present
If there is acute liver failure
What are the two frequently utilized diagnostic modalities in the pt who is acutely ill in order to determine if infection, a bile leak or biliary obstruction is present?
Serum bilirubin level
HIDA or DISIDA scan
RFs for the development of symptomatic gallstone dz
Obesity
Rapid weight loss or gain
Estrogen exposure
Classification of gallstones
Classified by their composition:
- Cholesterol stones
- Pigment stones
Further subdivision of pigment stones
Black or brown pigment stones
When do gallstones become symptomatic?
When they obstruct ductal structures
Presentation of biliary colic
RUQ pain, nausea and vomiting that commonly begins a few hours after a fatty meal but ultimately regresses spontaneously once the gallstone dislodges from the cystic duct
What is the term when gallstones intermittently obstruct the cystic duct?
Biliary colic
Tx of choice for cholelithiasis
Elective cholecystectomy
Sx of cholecystitis
Initially resemble those of biliary colic; however the pain persists for hours to days without resolution
PE of cholecystitis
Murphy’s sign
Febrile
Leukocytosis
What is often diagnostic of cholecystitis?
U/s