Osler, part 2 Flashcards
HPI of pancreatic CA
Gradual onset
Pain in lower back or epigastric, straight through to back
Fairly constant, worse at night
Dull, gnawing, visceral quality
Better when sitting up or leaning forward or fetal position +/- worse with eating/laying supine
Related sx of pancreatic CA
Wt loss Anorexia Generalized malaise and weakness New onset DM Jaundice (early sign of pancreatic head due to bile duct obstruction) Pruritis Acholic stools Dark urine
PE of pancreatic CA
Courvoisier's sign: Palpable, nontender, distended GB associated with jaundice \+/- hepatomegaly \+/- RUQ mass Cachexia \+/- superficial thrombophlebitis
Signs of metastasis of pancreatic CA
Abdominal mass Ascites L supraclavicular LAD (Virchow's node) Periumbilical mass (Sister Mary Joseph's node) Palpable rectal shelf
Grey Turner’s sign
Bruising of the flanks
Appears as blue discoloration
Sign of retroperitoneal hemorrhage
Workup for pancreatic CA
MRI
CT with IV contrast
ERCP: useful if obstructive jaundice, or sx without evidence of mass on CT
EUS (endoscopic u/s): clarification of small (<2 cm) lesions in neg/equivocal CT findings
CA 19-9: post-op monitoring
Tissue dx not necessary unless neoadjuvant therapy is planned
Purpose of Nissen fundoplication
Treats refractory GERD to prevent Barrett’s esophagus
Pre-op evaluation of Nissen fundoplication
Most important test is upper endoscopy Esophageal manometry pH testing UGI series Esophagogram
HPI of GERD
In chest/throat Burning Severity around 5 Comes and goes Wheezing, CP, dysphagia
Sx of GERD- refractory
Sore throat Hoarseness Trouble swallowing Cough Noncardiac CP
Indications for TURP or open simple prostatectomy
Acute urinary retention
Persistent or recurrent UTIs
Significant hemorrhage or recurrent hematuria
Bladder calculi secondary to bladder outlet obstruction
Significant sx from bladder outlet obstruction that are not responsive to medical or minimally invasive therapy
Renal insufficiency secondary to chronic bladder outlet obstruction
S/sx of prostate CA
Urinary frequency Urgency Nocturia Hesitancy Hematuria- uncommon presentation Hematospermia- uncommon presentation
Major RF for prostate CA
Smoking
1st degree relatives also a RF
Labs/diagnostics for prostate CA
PSA levels
Prostate bx guided by TRUS
RFs for prostate CA
AA > whites
Genetic- BRCA2 mutation
Smoking
Diet- high red meat diet
USPSTF guidelines for prostate CA
Decisions about screening should be make on an individual basis after consultation with a provider (C Recommendation)
Recommends against PSA-based screening past the age of 70 (D recommendation)
Labs and decision making process for thyroid nodules- initial
Check TSH and T3/4
Order u/s
Labs and decision making process for thyroid nodules- low TSH
Order iodine uptake
If no increase uptake, then order FNA
If increased, so no FNA
Indeterminant: get FNA
Labs and decision making process for thyroid nodules- high or nl TSH
Cystic nodules need no further testing
Spongiform > 2 cm
Hyperechoic >1.5 cm
Hypoechoic >1 cm need FHx of thyroid CA
What should be done for thyroid nodules if you did not do an FNA?
F/u in 6-12 mos
In anaplastic thyroid CA, what is the tx?
Needs palliative surgery only
What categories of FNA bx are considered to be surgical?
FN/SFN
SFM
MGT