Pathology Flashcards
what cell does a vestibular schwannoma originate from?
myelin forming cells (schwann) of CN8
what is a vestibular schwannoma?
benign primary intracranial tumour
where usually is a vestibular schwannoma?
temporal bone
who gets vestibular schwannomas (2 groups)?
sproradic (unilateral)
young (+ bilateral = NF2)
clinical features of NF2?
bilateral vestibular schwannomas
multiple meningiomas
gliomas
symptoms of vestibular schwannoma?
progressive ipsilateral tinnitus
sensorineural deafness
(due to cochlear nerve compression)
investigation for unilateral tinnitus?
MRI!!!!!!!!!!!
treatment for vestibular schwannoma?
surgery
in ENT, where can paragangliomas occur?
throat (non chromaffin)
who gets paragangliomas?
> 50, feature of MEN2
what virus is related to squamous papillomas in the throat?
HPV types 6 and 11
what is differences in squamous papillomas in adults and children?
adults - solitary, often not 6 and 11 related (laryngeal papillomatosis)
children - aggressive
risks for SSC in head and neck?
alcohol
smoking
HPV type 16
what is a contact ulcer?
benign response to injury
features of a contact ulcer?
ulceration
granulation tissue