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Reproductive > Pathology > Flashcards

Pathology Flashcards

1
Q

Early secretory phase characterized by ?

A

Sub nuclear vaculations

And tortuous glands

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2
Q

Late secretory characterised by?

A

Pre decidual change
Saw toothed glands
Secretions within the glands

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3
Q

Define metorehagia?

A

Irregular intervals exessive flow and duration

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4
Q

Types of endometrial cancers

A

Serous
Clear cell
Endometrioid

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5
Q

Mutations of endometrioid cancers?

A

PTEN

p53

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6
Q

Chronic anovulation is caused by static levels of ?

A

LH

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7
Q

Where does feral blood come in close proximity to maternal blood for gas exchange?

A

Chorionic villus

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8
Q

Why c section indicates in placenta previa?

A

Placenta covers the internal os that might lead to placental rupture and fatal maternal haemorrhage

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9
Q

Life threatening postpartum bleeding cause ?

A

Placenta accreta

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10
Q

Cloudy purulent exudate with chorion amnion of neutrophils, edema, congestion?

A

Acute chrorioamnionitis

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11
Q

Which pathology raise fetal death risk by affecting rate at which nutrients and gases are exchanged?

A

Villitis

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12
Q

Complications due to systemic endothelial dysfunction associated with pre eclampsia?

A

Acute renal failure
Hypercoagubility
Pulmonary Deema

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13
Q

What is hellp syndrome ?

A

Microangiopathic hemolytic anemia
Elevated Liver enzymes
And low platelets

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14
Q

How are we sure that preeclampsia caused by placenta?

A

When placenta is delivered the symptoms disappear

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15
Q

Reduced endothelial production of PGI2 causes?

A

Helypercoagulbility because anti thrombotic

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16
Q

Retroplacental hematomas are seen with?

A

Pre eclampsia

17
Q

4 pathological changes with preeclampsia?

A

Infarcts
Exaggerating ischemic changes
Retroplacental hematomas(bleeding and instability of uteroplacental vessels)
Abnormal decidual vessels

18
Q

Thin walled translucent cystic Grapelike swollen edematous chorionic villus

A

Hydatidform moles

19
Q

Cystic swelling of chorionic villus?

A

Hydadtidorm mole

20
Q

Characteristics of choriocarcinoma?

A

Rapidly invasive and metastatize widely

But responds to chemotherapy

21
Q

Choriocarcinoma tends to invade and penetrate

A

Myometrium
Blood vessels
Sometimes extend to serosa and adjacent structures

22
Q

What increases risk of corpus luteum cyst?

A

Clomphene

23
Q

What characterize endometriod cyst?

A

Endometrial lining and hemosidren laden macrophages

24
Q

3 major types of ovarian every epethelial cancers?

A

Serous, mucinous, endxometrioid

25
Q

Difference between serous cytoadenoma and serous carcinoma?

A

Cytoadenoma is smooth walled with no epethelial thickening due to papillary projections
But papillae sometimes seen
No psamomma bodies

26
Q

What makes papillary serous borderline tumor?

A

Good prognosis but stratification and nuclear atypia is observed

27
Q

Solid cystic unilateral mass of fibrous stroma with coffee bean appearance

A

Brenner

28
Q

Malignant germ cell tumours

A

Choriocarcinoma
Granulosa cell tumor
Endodermal sinus tumor

29
Q

Highly aggressive tumor of children or young women rich in alpha fetoprotein or alpha antitrypsin with schillar duval bodies positive for PAS

A

Endodermal sinus yolk sac tumor

30
Q

Acidophilus gland like tumor of estrogen producing call exener bodies tumor?

A

GCT

31
Q

Megis syndrome?

A

Hydrothorax and ascites with fibroma

32
Q

Thecoma or fibroma produces

A

Estrogenic manifestations

33
Q

Multi modularity and bilateral ovarion masses with mucin filled signet ring implies

A

Krukenburg

34
Q

Spiral arteries on endometrium constricts because ?

A

No progesterone received

35
Q

Proliferative phase characteristics

A

Round glands and mitosis

36
Q

Basal endometrium is re epitheliazed by?

A

Estrogen?

37
Q

Causes of endometrial hyperplasia

A

Obesity ( peripheral conversion of androgens)

GCT of ovary

Menopause

PCOD

Prolonged estrogen replacement therapy

Reproductive (6 decks)

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