Pathologies Flashcards

1
Q

sudden weakness or paralysis of the muscles on one side of the face, usually UNILATERAL but may be BILATERAL
temporary

A

Bell’s Palsy

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2
Q

what type of condition is bells palsy

A

a demyelinating condition

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3
Q

causes bells palsy

A

mostly viral - herpes
surgery
injury
stress

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4
Q

sudden acute progressive bilateral scenting paralusis

A

neuritis Guillain-barre syndrome

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5
Q

type of condition Neuritis/Guillain-barre syndrome?

A

demyelinating

acute inflammatory demyelinating polyneuropathy

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6
Q

cause neuritis/guillain-barre sydrome

A

autoimmune usually after respiratory tract infection

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7
Q

how to treat neuritis/guillain-barre sydrome

A

medical emergency

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8
Q

complication neuritis - guillain barre syndrome

A

death by heart/respiratory failure

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9
Q

progressive demyelination of neurons (CNS, brain, spinal cord) & damage to myelin sheath causing impulse conduction and communication between nerves being disturbed

A

multiple sclerosis

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10
Q

symptoms MS

A

SENSORY, MOTOR, VISUAL degeneration
numbness, burning, tingling, blurred vision, progressive paralysis
cognitive impairment, fatigue, depression
muscle weakness, spasms
incontinence

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11
Q

cause MS

A

unknown

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12
Q

Motor Neuron disease/MS men or women?

A

MN - more men

MS - more women

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13
Q

age of onset MS/MN

A

MS - 20-50

MN - after 40, usually 50-70

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14
Q

most common form of MN disease

A

ALS (Lou Gehrig’s disease)

also PLS, PMA, PBP

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15
Q

cause MN

A

unknown

suspected link genetics/toxic environment

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16
Q

most common symptom of ALS

A

muscle weakness

17
Q

early symptoms of ALS

A

progressive muscle weakness
twitching (at rest) of hands, arms
facial drooping (bulbar palsy)

18
Q

late symptoms ALS

A

legs & feet - dragging/tripping
voice changes
slurred speech
swallowing difficulties

19
Q

prognosis ALS

A

death by respiratory failure 3-5 yrs

20
Q

2 types dementia

A

vascular dementia

alzheimers disease

21
Q

neurodegenerative disease of cerebral cortex associated with abnormal protein deposition, destroying neurone that secrete acetylcholine. most common type of dementia

A

alzheimers disease

22
Q

cause alzheimers

A

unknown - aluminium link huge

23
Q

starts with inability to incorporate new knowledge, despite retention of old information. leads to dematia

A

alzheimers

24
Q

prognosis alzheimers

A

8-10 yrs after symptoms develop

25
Q

slow, progressive neurological disorder associated with degeneration of neurone in various parts of the brain, primarily the dopaminergic neurone in the substantial nigra.
dopamine deficiency
affects approx 1% of people older than 60

A

parkinsons

26
Q

inherited neurodegenerative disorder affecting brain 7 basal ganglia which affects muscle coordination and some cognitive functions. The most common genetic cause of abnormal involuntary writhing movements called chorea

A

Huntington’s disease

27
Q

huntington’s disease inherited lack of

A

GABA

28
Q

3 cardinal signs parkinsons

A

Bradykinesia - low voice, shuffling steps
resting tremors - jerky movements
rigidity - muscle stiffness, mask like face
(same as ALS)