CNS intro Flashcards
CNS consists of
Brain
Spinal cord
spinal cord protected by
vertebral column
brain protected by (4)
cranium
cranial meninges
cerebro-spinal fluid (CSF)
blood-brain barrier
three layers of connective tissue that cover the brain and spinal cord
meninges
3 layers of meninges
Dura mater - tough outer
arachnoid mater - stringy, elastic
pia mater - delicate
clear liquid that protects the brain & spinal cord from trauma and chemical injuries
cerebro-spinal fluid
CSF made from
filtered blood, water, Ions and glucose
4 functions CSF
supports/protects brain/spinal cord
maintains uniform pressure around brain
keeps moist
circulates nutrients/waste
the blood brain barrier protects the brain from
toxins, harmful substances and bacteria that enter the bloodstream by maintaining the tightness of capillaries and the junctions between cells
the BBB is maintained by
astrocytes
can lipid soluble substances cross the BBB - alcohol,anaesthaetics
yes easily
can glucose cross the BBB
yes by active transport
can gasses cross the BBB
yes diffuse easily
can ions cross the BBB
yes diffuse slowly across
can proteins pass the BBB
no