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Immunology Introduction FA > path - tumor markers and oncogenic microbes > Flashcards

path - tumor markers and oncogenic microbes Flashcards

1
Q

PSA

A

prostatic specific antigen
used to follow prostatic carcinoma
can also be elev in BPH and prostitis

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2
Q

Prostatic Acid Phosphatase

A

prostate carcinoma

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3
Q

CEA

A

CarcinoEmbryonic Antigen
non-specific but produced by 70% of colorectal and panc cancer
also prod by gastric, breast, and medullary thyroid carcinoma

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4
Q

alpha-fetoprotein

A

normally made by fetus
hepatocellular carcinomas
nonseminomatous germ cell tumors (ie testis, ovary)

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5
Q

Beta-hCG

A

Hydatidiform moles
Choriocarcinomas (Gestational trophoblastic dz)
hCG - commonly assoc with pregnancy

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6
Q

CA-125

A

ovarian cancer

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7
Q

S-100

A

melanoma, neural tumors, schwannomas

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8
Q

Alkaline Phosphatase

A

metastatis to bone, liver, Paget’s dz of bone

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9
Q

Bombesin

A

neuroblastoma, lung and gastric cancer

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10
Q

TRAP

A

Tartrate-Resistant Acid Phosphatase (TRAP)
HAIRY cell leukemia - a B cell neoplasia
TRAP the HAIRY animal

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11
Q

CA-19-9

A

pancreatic adenocarcinoma

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12
Q

calcitonin

A

medullary thyroid carcinoma

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13
Q

oncogenic microbes: HTLV-1

assoc cancer?

A

adult T cell leuk/lymphoma

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14
Q

oncogenic microbes: HBV, HCV

assoc cancer?

A

hepatocellular carcinoma

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15
Q

oncogenic microbes: EBV

assoc cancer?

A

burkitt’s lymphoma, Hodgkins, nasopharyngeal carc, CNS lymphoma (in immunocomp)

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16
Q

oncogenic microbes: HPV

assoc cancer?

A

cervical carc (16,18), penile/anal carc, upper resp SCC

17
Q

oncogenic microbes: HHV-8 (Kaposi sarcoma - assoc herpesvirus)
assoc cancer?

A

kaposi sarcoma, body cavity fluid B cell lymphoma

18
Q

oncogenic microbes: H.pylori

assoc cancer?

A

Gastric adenocarcinoma and lymphoma

19
Q

oncogenic microbes: schistosoma haematobium

assoc cancer?

A

bladder cancer (squamous cell)

20
Q

oncogenic microbes: liver fluke (Clonorchis sinensis)

assoc cancer?

A

Cholangiocarcinoma

Immunology Introduction FA (4 decks)

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