Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Maddy - GI II Exam I - some pharm > Path - Oral Cavity and Salivary Glands > Flashcards

Path - Oral Cavity and Salivary Glands Flashcards

1
Q

associated systemic dzs w/ periodontitis

A
  • AIDS
  • leukemia
  • Crohn’s
  • DM
  • Down’s
  • sarcoidosis
  • Chediak-Higashi syndrome
  • agranulocytosis
  • cyclic neutropenia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

describe clinical presentation of recurrent herpetic gingivostomatitis

A

1-3 mm groups of vesicles on lips, nasal orifices, buccal mucosa, gingiva, and hard palate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

demographic pyogenic granumola

A
  • children
  • young adults
  • pregnant women
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

salivary gland ductal obstruction due to stones

A

sialolithiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

focal demineralization of enamel and dentin by acidic metabolites of fermented sugar produced by bacteria

A

dental carries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how are odontogenic keratocysts different from regular odontogenic cysts

A

ondoctogenic keratocysts are agressive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

mucocele specifically of sublingual gland

A

ranula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

mass on lower lip secondary to trauma

A

mucocele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

painless, slow growing, mobile (if superficial) benign tumors within parotid or submandibluar areas or in buccal cavity

A

pleomorphic adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

complications of dental carries

A
  • weight loss
  • pain
  • life-threatening infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

most common fungal infection of oral cavity

A

c. albicans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

sticky, colorless biofilm that collects b/w and on surface of teeth

A

dental plaques

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

small, poorly encapsulated, infiltrative, pink-gray lesions

A

adenoid cystic carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

tumor in parotid and submandibular glands that grows along nerves (perineural)

A

adenoid cystic carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

recurrent herpetic gingivostomatitis may persist in ____ patients

A

immunocompromised

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

HPV-associated and non-HPV-associated squamous cell carcinoma are found in what areas of the head and neck

A

HPV-associated: oropharynx

not HPV associated: oral cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

TP53, P63, and NOTCH1 gene mutations

A

classic (tobacco) associated SCC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

describe clinical presentation of acute herpetic gingivostomatitis

A

abrupt onset of diffuse oral vesicles w/ ulceration, lymphadenopathy, fever, anorexia, and irritability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

clinical presentation of xerostomia

A
  • oral dryness
  • tongue fissuring
  • inflammatory salivary gland enlargement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

benign mass made of up a mixture of ductal (epithelial) and myoepithelial cells

A

pleomorphic adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

mass due to ductal blockage or rupture with saliva leaking into surround stroma

A

mucocele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

3 types of clinical presentation of c. albicans

A
  • pseudomembranous (thrush)
  • erythematous
  • hyperplastic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

a carcinoma that arises from pleomorphic adenoma

A

carcinoma ex pleomorphic adenoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

complications of xerostomia

A
  • increased rate of dental caries
  • candidiasis
  • difficulty swallowing and speaking
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

histology shows upper layer of columnar cells and lower layer with cuboidal to polygonal cells

A

warthin tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

local and distal invasion sites of SCC

A

local: submandibular and cervical LNs
distal: lungs, liver, bones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

mechanisms of activation of herpes simplex virus

A
  • UV light
  • URI
  • menstruation
  • immunosuppression
  • temperature extremes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

prognosis of SCC for tobacco and HPV associated

A

5 year survival rate:

  • early stage tobacco-related: 80%
  • late stage tobacco-related: 20%
  • HPV: better prognosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

histology shows lots of mitochondria that look oncocytic

A

warthin tumor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

common locations of odontogenic keratocysts

A

posterior mandible (jaw/jawbone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

acute pharyngitis and tonsillitis that causes gray-white exudative membrane, enlargement of LN in neck, palatal petechiae

A

infectious mono

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

white-coated tongue through which hyperemic papillae project

A

“strawberry tongue” from scarlet fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

fiery red tongue with prominent papillae

A

“raspberry tongue” from scarlet fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

P16 activation

A

HPV associated SCC

35
Q

causes of xerostomia

A
  • autoimmune inflammation and fibrosis (Sjogren)
  • radiation therapy
  • anticholinergics
  • nerve damage, stroke, tobacco, aging
36
Q

slow growing, uncommon tumor in parotid and submandibular glands

A

adenoid cystic carcinoma

37
Q

round to oval encapsulated mass 2-5cm in diameter arising in superficial parotid gland where it is readily palpable

A

warthin tumor

38
Q

risk factors for squamous cell carcinoma of the oral cavity and oropharynx

A
  • alcohol and tobacco use
  • actinic radiation
  • pipe smoking
  • betel quid nut and paan chewing
  • genetics
39
Q

histology shows intercellular bridges in stratified squamous epithelium

A

SCC

40
Q

inflammation of oral mucosa around teeth due to accumulation of dental plaque and calclulus

A

gingivitis

41
Q

recurrent, painful superficial oral mucosal ulcerations of unknown etiology

A

aphthous ulcers (canker sores)

42
Q

what syndromes can odontogenic keratocysts be associated with

A

Gorlin syndrome (nevoid basal cell carcinoma syndrome)

43
Q

compare prognosis b/w HPV-associated and non-HPV-associated squamous cell carcinoma

A

better prognosis WITH HPV-association

44
Q

most common primary malignant salivary tumor

A

mucopeidermoid carcinoma

45
Q

inflammation of oral glands

A

sialadenitis

46
Q

squamous cell carcinoma of the oral cavity and oropharynx is associated with what virus

A

HPV-16

47
Q

unilateral, painful submandibular gland enlargement and purulent discharge following sialolithiasis (duct obstruction from stones) caused by bacteria

A

nonspecific bacterial sialadenitis

48
Q

compare early and late stages of SCC in oral cavity

A

early: raised, firm, pearly, plaques or verrucous mucosal thickening
late: ulcerations or protrusions with irregular indurated borders

49
Q

superficial gray-white inflammatory membranes composed of fibrinosuppurative exudates

A

pseudomembranous oral candidiasis (thrush)

50
Q

pt with predisposition to opportunistic oral infections including hairy leukoplakia

A

HIV

51
Q

mixture of bacteria, salivary proteins, desquamated epithelial cells on teeth

A

dental plaques

52
Q

most common type of inflammatory salivary gland lesion

A

mucocele

53
Q

benign tumor occurring almost exclusively in the parotid gland

A

warthin tumor

papillary cystadenoma lympomatosum

54
Q

epithelium lined cysts in the mandible and maxilla derived from odontogenic epithelium remnants

A

odontogenic cysts

55
Q

location of most mucopeidermoid carcinomas

A

most commonly in parotid glands

56
Q

small cells with dark, compact nuclei and scant cytoplasm, that are in tubular or cribriform patterns

A

adenoid cystic carcinoma

57
Q

demographic for pts w/ oral candidiasis

A
  • pts on broad spectrum antibiotics
  • DM
  • neutropenia
  • organ/bone marrow transplants
  • immunodeficiency
58
Q

describe histological progression of oral SCC

A

hyperplasia –> mild/moderate dysplasia –> severe dysplasia/CIS –> SCC

59
Q

SCC with preceding cancerous lesion

A

classic (tobacco) associated SCC

NOT HPV

60
Q

red, velvety, eroded area of oral cavity

A

erythroplakia

61
Q

most common form of viral dialadenitis

A

mumps

62
Q

submucosal nodular mass of fibrous connective tissue stroma due to repetitive trauma

A

traumatic fibroma

63
Q

dirty white, fibrinosuppurative, tough, inflammatory membrane over tonsils and retropharynx

A

diptheria

64
Q

pale grey-white mass with no capsule and small mucin containing cysts

A

mucopeidermoid carcinoma

65
Q

causes of sialadenitis

A
  • autoimmune (sjogren’s)
  • mumps
  • trauma (mucocele)
66
Q

compare malignant transformation potential b/w leukoplakia and erythroplakia

A

erythroplakia has severe dysplasia with greater risk of malignant transformation

67
Q

spotty enanthema in oral cavity, ulcerations in buccal mucosa, Koplik spots

A

measles

68
Q

white patch or plaque of oral cavity that cannot be scraped off

A

leukoplakia

69
Q

most common cause tooth loss <35

A

dental carries

70
Q

where does classic (tobacco) associated SCC arise in the oral cavity

A
  • ventral tongue
  • floor of mouth
  • lower lip
  • soft palate
  • gingiva
71
Q

rapidly growing, highly vascular proliferation of granular tissue in giniva

A

pyogenic granuloma

72
Q

describe clinical presentation of herpes labialis

A

1-3 mm lesions on lips

73
Q

demographic for leukoplakia and erythroplakia

A

40-70 y/o, males, tobacco use

74
Q

immunological disorders associated with aphthous ulcers (canker sores)

A
  • sprue
  • celiac’s
  • IBD
  • Behcet’s
75
Q

two main offenders for non-specific bacterial sialadenitis

A

s. aureus

strep. viridans

76
Q

blue translucent mass on lower lip

A

mucocele

77
Q

inflammation of supporting structures of teeth (periodontal ligaments), alveolar bone, cementum

A

periodontitis

78
Q

MECT1-MAML2 fusion gene translocation

A

mucopeidermoid carcinoma

79
Q

E6 and E7 expression leading to inactivation of p53 and RB

A

HPV associated SCC

80
Q

cyst like space lined w/ inflammation granulation tissue devoid of epithelial lining

A

mucocele

81
Q

compare warthin tumor and pleomorphic adenoma

A

both: benign, parotid gland
warthin: much more often in males, cigarette smoking, 10% bilateral

pleomorphic adenoma: ionizing radiation, PLAG1 overexpression

82
Q

PLAG1 overexpression

A

pleomorphic adenoma

83
Q

plummer-vinson syndrome (paterson-brown kelley syndrome) is associated with ______

A

esophageal WEBS

Maddy - GI II Exam I - some pharm (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions