Path

Question 0

Tyrosine kinase oncogenes

Answer 0

abl, erb-B2, ret

Question 1

OncoGene or tumor suppressor: L-myc, ret, BRCA, DPC,ras, bcl-2, NF1, APC, p53

Answer 1

Og,Og, ts, ts, Og, Og, ts, ts, ts

Question 2

Transcription factor oncogene

Answer 2

C-myc

Question 3

GTP-ase oncogene

Answer 3

Ras

Question 4

Cytokine receptor oncogene

Answer 4

C-kit

Question 5

Paraneoplastic syndrome with increased erythropoietin

Answer 5

Renal cell carcinoma, hepatocellular carcinoma, hemangioblastoma, pheochromocytoma

Question 6

Psammoma bodies

Answer 6

Papillary thyroid, ovary(serous), meningioma, mesothelioma

Question 7

Bence jones amyloid

Answer 7

AL (think Light chain from MM)

Question 8

Secondary amyloid

Answer 8

AA (assoc with chronic cond)

Question 9

Senile cardiac amyloid, transthyretin, derived from

Answer 9

AF

Question 10

DM II Amyloid

Answer 10

Amylin from AE (think Endocrine)

Question 11

Dialysis assoc amyloid

Answer 11

Beta 2 microglobulin (MHC class I proteins)

Question 12

Metastasis to the bone

Answer 12

Permanently relocated tumors like long bones

Prostate, renal, thyroid, testes, lung,
Lymphoma, breast

Question 13

Metastasis to brain

Answer 13

Lots of bad stuff kills glia

Lung, breasts, skin ,kidney, G.I.

Question 14

Metastasis to liver

Answer 14

Cancer sometimes penetrates benign liver

Colon, Stomach, pancreas, breast, lung