Immunology Flashcards

Question 1

Q

HLA B8

Question 2

Q

HLA A3

Answer

A

Hemochromatosis

Question 3

Q

HLA DR 2

Answer

A

Multiple sclerosis, hayfever, SLE, Goodpasture’s

Question 4

Q

HLA DR3

Answer

A

Diabetes type I

Question 5

Q

HLA DR5

Answer

A

Pernicious anemia, Hashimoto’s thyroiditis

Question 6

Q

C1 esterase inhibitor deficiency

Answer

A

Hereditary angioedema, ACE inhibitors contraindicated

Question 7

Q

C3 deficiency

Answer

A

Recurrent pyogenic sinus and respiratory tract infections susceptibility to type III hypersensitivity reactions

Question 8

Q

DAF deficiency

Answer

A

CD55, CD59 missing. Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria

Question 9

Q

AntiMitochondrial antibody

Answer

A

Primary biliary cirrhosis

Question 10

Q

Anti-histone antibody

Answer

A

Drug induced lupus

Question 11

Q

Anti-microsomal antibody

Answer

A

Hashimoto’s thyroiditis

Question 12

Q

Anti-smooth muscle antibody

Answer

A

Autoimmune hepatitis

Question 13

Q

Anti-glutamate decarboxylase antibodies

Answer

A

Diabetes type I

Question 14

Q

Anti-centromere antibody

Answer

A

Crest scleroderma

Question 15

Q

Monoclonal antibody that binds to CD three

Answer

A

Muromonab

Question 16

Q

Anti-metabolite precursor of 6-mercaptopurine

Answer

A

Azathioprine

Question 17

Q

Monoclonal antibody to IL-2 receptor

Answer

A

Daclizumab

Question 18

Q

Inhibits mTOR

Answer

A

Sirolimus

Question 19

Q

Binds FK binding proteins inhibiting secretion of I L2

Answer

A

Tacrolimus

Question 20

Q

Inhibits calcineurin preventing production of IL-2

Answer

A

Cyclosporine

Question 21

Q

Lymph drainage from rectum above pectinate line

Answer

A

Internal iliac

Question 22

Q

Lymph drainage from anal canal below pectinate line

Answer

A

Superficial inguinal

Question 23

Q

Lymph drainage from scrotum

Answer

A

Superficial inguinal

Question 24

Q

NK cell surface proteins

Macrophages

Answer

A

CD16, CD 56

CD14, CD 40