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Step 1 > Immunology > Flashcards

Immunology Flashcards

0
Q

HLA B8

A

Graves

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1
Q

HLA A3

A

Hemochromatosis

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2
Q

HLA DR 2

A

Multiple sclerosis, hayfever, SLE, Goodpasture’s

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3
Q

HLA DR3

A

Diabetes type I

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4
Q

HLA DR5

A

Pernicious anemia, Hashimoto’s thyroiditis

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5
Q

C1 esterase inhibitor deficiency

A

Hereditary angioedema, ACE inhibitors contraindicated

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6
Q

C3 deficiency

A

Recurrent pyogenic sinus and respiratory tract infections susceptibility to type III hypersensitivity reactions

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7
Q

DAF deficiency

A

CD55, CD59 missing. Complement mediated lysis of RBCs and paroxysmal nocturnal hemoglobinuria

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8
Q

AntiMitochondrial antibody

A

Primary biliary cirrhosis

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9
Q

Anti-histone antibody

A

Drug induced lupus

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10
Q

Anti-microsomal antibody

A

Hashimoto’s thyroiditis

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11
Q

Anti-smooth muscle antibody

A

Autoimmune hepatitis

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12
Q

Anti-glutamate decarboxylase antibodies

A

Diabetes type I

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13
Q

Anti-centromere antibody

A

Crest scleroderma

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14
Q

Monoclonal antibody that binds to CD three

A

Muromonab

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15
Q

Anti-metabolite precursor of 6-mercaptopurine

A

Azathioprine

16
Q

Monoclonal antibody to IL-2 receptor

A

Daclizumab

17
Q

Inhibits mTOR

A

Sirolimus

18
Q

Binds FK binding proteins inhibiting secretion of I L2

A

Tacrolimus

19
Q

Inhibits calcineurin preventing production of IL-2

A

Cyclosporine

20
Q

Lymph drainage from rectum above pectinate line

A

Internal iliac

21
Q

Lymph drainage from anal canal below pectinate line

A

Superficial inguinal

22
Q

Lymph drainage from scrotum

A

Superficial inguinal

23
Q

NK cell surface proteins

Macrophages

A

CD16, CD 56

CD14, CD 40

Step 1 (12 decks)

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