Endocrine Flashcards
Decrease gluconeogenesis increase peripheral glucose uptake
Biguanide like Metformin
Diabetes drugs close potassium channel in beta cells triggering release of insulin
Interesting SE
Sulfonylureas like glyburide
Disulfiram-like rxn with first gen
Increase insulin sensitivity and peripheral tissue binds to PPAR Gamma ( intracellular receptor)
SEs
Glitazones
Weight gain and edema, hepatotox, heart failure
Name drugs that inhibit intestinal brush border alpha glucosidases
Acarbose, miglitol
Name GLP 1 Analogs which increase insulin and decrease glucagon release
Exenatide
Name drug that increases insulin and decreases glucagon release by inhibiting DPP
Sitagliptin
Treatment for nephrogenic DI
Hydrochlorothiazide, indomethacin, or Amelioride