Endocrine Flashcards

0
Q

Decrease gluconeogenesis increase peripheral glucose uptake

A

Biguanide like Metformin

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1
Q

Diabetes drugs close potassium channel in beta cells triggering release of insulin

Interesting SE

A

Sulfonylureas like glyburide

Disulfiram-like rxn with first gen

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2
Q

Increase insulin sensitivity and peripheral tissue binds to PPAR Gamma ( intracellular receptor)
SEs

A

Glitazones

Weight gain and edema, hepatotox, heart failure

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3
Q

Name drugs that inhibit intestinal brush border alpha glucosidases

A

Acarbose, miglitol

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4
Q

Name GLP 1 Analogs which increase insulin and decrease glucagon release

A

Exenatide

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5
Q

Name drug that increases insulin and decreases glucagon release by inhibiting DPP

A

Sitagliptin

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6
Q

Treatment for nephrogenic DI

A

Hydrochlorothiazide, indomethacin, or Amelioride

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