Past questions Flashcards by Benedicte Mæhlum

which drug can be effective agaisnt MRSP?

Amikacin
fusidic acid
both
none

both

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Most typical mechanism of action of real restistance of fipronil :
Alteration of nicotinergic receptors
Beta-tubulin binding site change
increased metabolic action
Ligand mediated chloride ion channel intracellular domain alteration

Ligand mediated chloride ion channel intracellular domain alteration

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What is the route of admin for colistin in swine?

IM (but not really used)

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fowl cholera cause high mortality in this species:
Duck 
Turkey 
Laying hen 
Quail

Duck’

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What agent could be first-line in chronic rhinitis in dogs and cats?
Penicillin 
none 
enrofloxacin 
both

none

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What agents could be first-line choice in chronic rhinitis in dogs and cats?
gentamicin 
doxycycline 
both 
none

Doxycycline

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what agent could be first-line choice in chronic rhinitis in dogs and cats?
Doxycycline 
both 
none 
Azithromycin

Both

but doxy is the nr.1, but azithro can be used aswell

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What is the route of admin for amoxicillin and clavulanic acid in swine ?
PO
IM
none
both

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Which statement is true about the following sentence? Florfenicol and tiamulin combination is synergistic against ornithobacterium rhinotracheale, because they inhibit protein synthesis on different targets:

The whole sentence is true
Only the first part is true
Only the second part is true
The whole sentence is false

The whole sentence is false

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In poultry, e.coli can cause:
Septicaemia 
CRD
both 
none

both?

CRD- yes, colisepsis = septicaemia?

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in poultry, E.coli can cause :
Granulomatosis 
arthritis 
both 
none

both

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Which agent would be a first-line choice in acute pharyngitis in dogs?
Azithromycin 
penicillin 
gentamicin 
enrofloxacin

Penicillin (narrow)

Real answer is cephalosporin

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in poultry, E.coli can cause :
Pericarditis 
salpingitis  
both 
none

both

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What is the route of admin for lincomycin in swine?
PO
IM
none
both

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Which agent would be a first-line choice in CHRONIC pharyngitis in dogs?
Azithromycin 
penicillin 
gentamicin 
enrofloxacin

Azithromycin

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Which agent would be a first-line choice in CHRONIC rhinitis in dogs?
Doxycycline
penicillin 
gentamicin 
enrofloxacin

Doxycycline

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Which drug belongs to the first line systemic treatments for canine pyoderma?
Amox + clav
cefovecin 
both 
non

both

but avoid cefovecin!

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Which drug can be used for systemic treatment of MRSP pyoderma in dogs?
fusidic acid 
cefovecin 
none
both

none?

not systemic

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Which drug can be used for systemic treatment of MRSP pyoderma in dogs?
florfenicol
amikacin
none
both

both

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Which AB combinations would be recommended in pneumonia in dogs?
amox + clav + enrofloxacin 
cefuroxime + marbofloxacin 
none 
both

both

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minocycline belongs to 
monobactams
glycopeptides
tetracycline 
macrolides

tetracyclines

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Tulathromycin belongs to 
aminoglycosides 
lincosamides
monobactams 
macrolides

macrolides

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imipenems belongs to 
rifamycin
monobactams 
carbapenems 
glycopeptides

carbapenems

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clincamycin belongs to 
lincosamides
glycopeptides
tetracycline 
macrolides

lincosamides

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``` PotSA are conc dep bactericidal bacteriostatic time dep bactericidal none ```

Time dep cidal | alone static

``` gamithromycin belongs to aminoglycosides lincosamides glycopeptides macrolides ```

macrolides

``` polymyxin are conc dep bactericidal bacteriostatic time dep bactericidal none ```

conc dep bactericidal

``` neomycin belongs to aminoglycosides lincosamides glycopeptides macrolides ```

aminoglycosides

``` enrofloxacin are: 1st gen 2nd gen 3rd gen 4th gen ```

2nd gen fluoroquinolones

``` Diclocacillin belongs to the Broad spectrum pencillins Pencillinase-resistant pencilins narrow spectrum penicillins tetracyclines ```

Pencillinase-resistant pencilins

``` Pleuromutulins are: conc dep bactericidal bacteriostatic time dep bactericidal none ```

bacteriostatic (50s)

How should time dependent bactericidal antibiotics be given? A. At least 3-5 days, in high dose (which reach 8 times higher conc in the animals than the MIC value of the pathogen) B. For a short time 1-2 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen) C. At least 3-5 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen) D. For short time 1-2 days , high dose (which reach 8 times higher conc in the animals than the MIC value of the pathogen)

C. At least 3-5 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen)

``` Ceftiofur is : 4th gen 2nd gen 1st gen 3rd gen ```

3rd gen

``` Marbofloxacin belongs to: AMEG A AMEG B AMEG C AMEG D ```

AMEG B

``` Is it allowed to use veterinary AB for the purpose of preventing infectious diseases according to the law in force? Not allowed allowed only in pet animals only in FPA ```

allowed

``` What is the route of admin for marbofloxacin in swine? PO both none IM ```

IM only

``` What is the route of admin for ceftiofur in swine? PO both none IM ```

IM only

``` How can we prevent AB resistance? Perform a PK(PD analysis Use AB for prevention and not for treatment Both non ```

Perform a PK(PD analysis

How would you define the MIC? A. The highest concentration of the AB, where bacteria can't grow. B. The mean concentration of the AB, where bacteria can't grow. C. The lowest concentration of the AB, where bacteria can't grow. D. The median concentration of the AB, where bacteria can't grow.

C. The lowest concentration of the AB, where bacteria can't grow.

Is it legal to give an AB authorized for dogs to cats? it is legal in every case yes it is, if no authorized product is available and it is not contraindicated by the SPC of that product. Only if there are no SE in cats Only in adult cats

yes it is, if no authorized product is available and it is not contraindicated by the SPC of that product.

``` Which susceptibility method can be used for PK/PD analysis? Disk diffusion method both microdilution none ```

microdilution

What is metaphylaxis? A. the admin of medical product to a group of animala before clinical signs of a disease, in order to prevent the occurence of disease or infection B. the admin of medical product to a group of animal after a diagnosis of clinical disease in part of the group has been established

B. the admin of medical product to a group of animal after a diagnosis of clinical disease in part of the group has been established

``` Most typical mechanism of action of decreased susceptibility to organophosphates: Increased CYP-enzyme activity Increased efflux Increased transport Increased activity of esterase enzymes ```

Increased activity of esterase enzymes

``` Cefquinome belongs to: AMEG A AMEG B AMEG C AMEG D ```

AMEG B

which statement is true about BRDC? a. fastidious organism are the most frequent bacteria present. unfortunately, resistance is usually high in them to most AB b. mycoplasma are the most frequent bacteria present. luckily resistance usually low in them to most AB. c. fastidious organisms are the most frequent bacteria present, resistance is usually low inn them to ABs. d. mycoplasma ar the most frequent , unfortunately resistance is usually high .

c. fastidious organisms are the most frequent bacteria present, resistance is usually low inn them to ABs.

``` Which drug can be effective agaisnt MRSP? cefovecin both mupirocin none ```

Mupirocin

Which statement is true about the following sentence? Pseudomonas aeruginosa is a frequent causes of suppurative otitis externa, which is sensitive to alkalic environment? The whole sentence is true only the second part only the first part the whole is false

only the first part

Which statement is true about the following sentence? in case of damanged eardrum, tobramycin and marbofloxacin ear drops can be used, because only polymyxines are ototoxic. The whole sentence is true only the second part only the first part the whole is false

the whole is false

``` signle shot products contain: Time dep bactericidal bacteristatic conc dep bactericidal all of them ```

conc dep bactericidal

``` Single shot AB can be used against : GI infections foot infection none both ```

none

``` sulphonamides are: con dep cidal time dep cidal bacteriostatic none ```

bacteriostatic

``` Pradofloxacin are: 1st gen 2nd gen 3rd gen 4th gen ```

4th gen

``` Which drug can be used topically to treat canine pyoderma? Azithromycin silver sulfadiazine both none ```

both

``` Which drug belongs to the first line systemic treatment of pyoderma? cirpofloxacin both cefalexin none ```

cefalexin | cirpo- 2ndline

what statement is true about the following sentence? Tris-EDTA is recommended agent in otitis externa, because it has a good antibiofilm effect all is true first is true second part is true all false

all is true

``` Valnemulin belongs to: Glycopeptides lincosamide macrolides pleuromutilins ```

pleuromutilins

``` pleuromutilins are conc dep cidal time dep cidal none bacteriostatic ```

bacteriostatic

Which pathogen is most frequent in phayngitis in companion animals? Streptococci in cats , pasteurella in dogs Streptococci in dogs, pasteurella in cats Staphylococcus in cats , pasteurella in dogs Staphylococcus in dogs , pasteurella in cats

Streptococci in dogs, pasteurella in cats

``` In which respiratory infection is it necessary to use antibiotics? Calicivirus in cats canine distemper herpes in cats aspergillosis in dogs ```

canine distemper

``` does present law allow mixing of AB into feed of animals? no yes only to mix on ab at the time only for pigs ```

yes

``` which drug are 1st line of pyoderma? metronidazole both clindamycin none ```

clindamycin

``` which drug are 1st line of pyoderma? amox + clav both cefovecin none ```

both

``` Route of admin tilmicosin in swine: IM PO both none ```

``` Route of admin enrofloxacin in swine: IM PO both none ```

both

``` What is true? It is enough to treat supf. pyoderma only topical , because bacteria are only present on the skin surface in this case. Only the first is true only second is true all true all false ```

all false

``` What is recommended treatment duration in feline rhinotracheitis? 7-10 days in acute, 1-2w in chronic 7-10 days in acute, 4-6w in chronic acute never, chronic 4-6w acute never, chronic 1-2w ```

acute never, chronic 4-6w

``` Strepto and pasteurella frequently causes... in companion animals: Bronchitis, pneumonia rhinitis, sinusitis pharyngitis, tonsilitis all ```

all

How can we prevent ab resistance: Use ab for treatment, not prevention Must know pharmacodynamics of antibacterial agents Perform antibiotic susceptibility test regularly All

all

``` Route of amox + clav for Swine: PO IM both none ```

both

What route of admin - cefquinome in swine? PO IM both none

``` What route of admin - marbofloxacin in swine? PO IM both none ```

both

What is true: a. rhinitis is more freq caused by virus, but bacterial superinfection always occur, so ab prophylaxis is used. b. rhinitis is more freq caused by virus, so in many cases ab treatment is not necessary. c. fungi are the most freq cause, but these are selflimiting, so anti fungal treatment is not necessary. d. most cases of rhinitis is caused by bacteria, streptococci,staphylococci, pasteurella, but these are self-limiting , supportive therapy is sufficient.

b. rhinitis is more freq caused by virus, so in many cases ab treatment is not necessary.

``` Resistance rates are the worst in this species: poultry swine ruminants dogs ```

swine

``` Cefquinome belongs to: AMEG A AMEG B AMEG C AMEG D ```

for how long shall be valid a veterinary prescription for antimicrobial veterinary medicinal product from the date of its issue according to the new EU regulation of veterinary medicines? 10d 5d 30d its validity shall not be limited

``` Topical for pyoderma: enrofloxacin neomycin both none ```

neomycin

``` Florfenicol can have this side effect in dogs: KCS Anaemia both none ```

Anaemia (bone marrow suppression) | KCS = PotSA

what is true: Usually there's a background disease behind pyoderma, commonly allergy or parasite infection. all true all false first true second true

all true

what is true: Usually systemic is not needed in case of intertrigo, bacause bacteria cannot reach deeper parts of of the skin in this diseases. all true all false first true second true

all true

what is true: Consumption of fluoroquinolones should be decreased Consumption of colistin should be decreased both none

both (decreased)

what is general indication? a. The product is indicated against e.coli b. the indication says that the product is indicated against bacteria that are sensitive to AB c. the product is indicated for several bacteria which are listed in the indication d. in the indication of the product only the name of genus is included.

c. the product is indicated for several bacteria which are listed in the indication ??

what is true? Ceftiofur-HCl is turned to desfuroyl-ceftiofur slowly in the body Ceftiofur-HCl is turned to ceftiofur crystalline free acid quickly in the body Ceftiofur-HCl is turned to desfuroyl-ceftiofur quickly in the body Ceftiofur-HCl is turned to ceftiofur crystalline free acid slowly in the body.

Ceftiofur-HCl is turned to desfuroyl-ceftiofur quickly in the body

``` This drug is very effective against fastidious bacteria and mycoplasma as well and has excellent distribution. Tildipirosin both gamithromycin none ```

Gamithromycin

what is true about foot disease in ru? a. interdigital phlegmone, topical antibiotic therapy is enough, while interdigital dermatitis needs systemic therapy. b. both are enough to be treated with local AB and systemic NSAIDs c. interdigital dermatitis, topical antibiotic therapy is enough, while interdigital phlegmone needs systemic therapy. d. both need to be treated with systemic AB and NSAIDs

c. interdigital dermatitis, topical antibiotic therapy is enough, while interdigital phlegmone needs systemic therapy. ?

``` amox + clav are: AMEG A AMEG B AMEG C AMEG D ```

AMEG C

``` Used for foot rot that are good against anaerobic bacteria and penetration is good: lincomycin florfenicol both none ```

both

``` First choice in CIRDC: Doxycycline Clarithromycin both none ```

both

``` First choice in CIRDC: Doxycycline PotSA both none ```

both

``` this drug is not authorized for poultry in EU: chloramphenicol tiamulin tylvalosin phenoxymethylpenicillin ```

chloramphenicol

``` Which of the following bacteria can not produce beta lactamase enzymes? Staphylococcus aureus e.coli pasteurella multicida streptococcus suis ```

streptococcus suis?

``` recommended in dog pneumonia: Doxycycline + gentamicin amox + clav + gentamicin both none ```

amox + clav + gentamicin

``` not authorized in EU (poultry): amox + clav spectinomycin difloxacin colistin ```

CLAV!

``` in poultry, stahylococcus cause: septicaemia upper respiratory tract disease both none ```

Septicaemia

``` recommended in dog pneumonia: amox clav + cefuroxime amox clav + enrofloxacin both none ```

amox clav + enrofloxacin

``` not authorized in EU (poultry): gentamicin doxycycline lincomycin florfenicol ```

florfenicol

``` which of the following bacteria can cause polyserositis of swine? mycoplasma hyopneumoniae e.coli m.suis streptococcus suis ```

streptococcus suis

``` Pathogens of CIRDC: Bordetella bronchiseptica parainfluenza virus both none ```

both

``` How should ab be administered in case of pneumonia in dogs? SC IV Orally inhalationally ```

``` in poultry, staphylococcus aureus can cause: arthritis dermatitis both none ```

both

``` which agent is most effective in shampoos for cellulitis? ethyl lactate prioctone olamine benzoyl peroxide chlorine dioxide ```

benzoyl peroxide

``` How should amikacin be used to treat canine pyoderma? oral im both none ```

``` which drug combination would be recommended in aspiration pneumonia in dogs? amox + cefuroxime + metronidazole Amox + marboflox + metronidazole both none ```

none Broad spectrum beta-lactam + enrofloxacin (aminoglycoside) + metronidazole against anaerob

``` Metronidazole belongs to nitrofurans monobactams nitroimidazoles carbapenems ```

nirtoimidazole

``` Effective agaisnt fastidious bacteria and mycoplasma as well and has excellent distribution: enrofloxacin tulathromycin both none ```

both

``` which ab reach high conc intracellularly? penicillins cephalosporins macrolides all ```

macrolides