Past questions Flashcards
which drug can be effective agaisnt MRSP?
Amikacin
fusidic acid
both
none
both
Most typical mechanism of action of real restistance of fipronil :
Alteration of nicotinergic receptors
Beta-tubulin binding site change
increased metabolic action
Ligand mediated chloride ion channel intracellular domain alteration
Ligand mediated chloride ion channel intracellular domain alteration
What is the route of admin for colistin in swine?
IM (but not really used)
fowl cholera cause high mortality in this species: Duck Turkey Laying hen Quail
Duck’
What agent could be first-line in chronic rhinitis in dogs and cats? Penicillin none enrofloxacin both
none
What agents could be first-line choice in chronic rhinitis in dogs and cats? gentamicin doxycycline both none
Doxycycline
what agent could be first-line choice in chronic rhinitis in dogs and cats? Doxycycline both none Azithromycin
Both
but doxy is the nr.1, but azithro can be used aswell
What is the route of admin for amoxicillin and clavulanic acid in swine ? PO IM none both
PO
Which statement is true about the following sentence? Florfenicol and tiamulin combination is synergistic against ornithobacterium rhinotracheale, because they inhibit protein synthesis on different targets:
The whole sentence is true
Only the first part is true
Only the second part is true
The whole sentence is false
The whole sentence is false
In poultry, e.coli can cause: Septicaemia CRD both none
both?
CRD- yes, colisepsis = septicaemia?
in poultry, E.coli can cause : Granulomatosis arthritis both none
both
Which agent would be a first-line choice in acute pharyngitis in dogs? Azithromycin penicillin gentamicin enrofloxacin
Penicillin (narrow)
Real answer is cephalosporin
in poultry, E.coli can cause : Pericarditis salpingitis both none
both
What is the route of admin for lincomycin in swine? PO IM none both
IM
Which agent would be a first-line choice in CHRONIC pharyngitis in dogs? Azithromycin penicillin gentamicin enrofloxacin
Azithromycin
Which agent would be a first-line choice in CHRONIC rhinitis in dogs? Doxycycline penicillin gentamicin enrofloxacin
Doxycycline
Which drug belongs to the first line systemic treatments for canine pyoderma? Amox + clav cefovecin both non
both
but avoid cefovecin!
Which drug can be used for systemic treatment of MRSP pyoderma in dogs? fusidic acid cefovecin none both
none?
not systemic
Which drug can be used for systemic treatment of MRSP pyoderma in dogs? florfenicol amikacin none both
both
Which AB combinations would be recommended in pneumonia in dogs? amox + clav + enrofloxacin cefuroxime + marbofloxacin none both
both
minocycline belongs to monobactams glycopeptides tetracycline macrolides
tetracyclines
Tulathromycin belongs to aminoglycosides lincosamides monobactams macrolides
macrolides
imipenems belongs to rifamycin monobactams carbapenems glycopeptides
carbapenems
clincamycin belongs to lincosamides glycopeptides tetracycline macrolides
lincosamides
PotSA are conc dep bactericidal bacteriostatic time dep bactericidal none
Time dep cidal
alone static
gamithromycin belongs to aminoglycosides lincosamides glycopeptides macrolides
macrolides
polymyxin are conc dep bactericidal bacteriostatic time dep bactericidal none
conc dep bactericidal
neomycin belongs to aminoglycosides lincosamides glycopeptides macrolides
aminoglycosides
enrofloxacin are: 1st gen 2nd gen 3rd gen 4th gen
2nd gen fluoroquinolones
Diclocacillin belongs to the Broad spectrum pencillins Pencillinase-resistant pencilins narrow spectrum penicillins tetracyclines
Pencillinase-resistant pencilins
Pleuromutulins are: conc dep bactericidal bacteriostatic time dep bactericidal none
bacteriostatic (50s)
How should time dependent bactericidal antibiotics be given?
A. At least 3-5 days, in high dose (which reach 8 times higher conc in the animals than the MIC value of the pathogen)
B. For a short time 1-2 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen)
C. At least 3-5 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen)
D. For short time 1-2 days , high dose (which reach 8 times higher conc in the animals than the MIC value of the pathogen)
C. At least 3-5 days in the recommended doses (which reach higher conc in the animal than the MIC value of the pathogen)
Ceftiofur is : 4th gen 2nd gen 1st gen 3rd gen
3rd gen
Marbofloxacin belongs to: AMEG A AMEG B AMEG C AMEG D
AMEG B
Is it allowed to use veterinary AB for the purpose of preventing infectious diseases according to the law in force? Not allowed allowed only in pet animals only in FPA
allowed
What is the route of admin for marbofloxacin in swine? PO both none IM
IM only
What is the route of admin for ceftiofur in swine? PO both none IM
IM only
How can we prevent AB resistance? Perform a PK(PD analysis Use AB for prevention and not for treatment Both non
Perform a PK(PD analysis
How would you define the MIC?
A. The highest concentration of the AB, where bacteria can’t grow.
B. The mean concentration of the AB, where bacteria can’t grow.
C. The lowest concentration of the AB, where bacteria can’t grow.
D. The median concentration of the AB, where bacteria can’t grow.
C. The lowest concentration of the AB, where bacteria can’t grow.
Is it legal to give an AB authorized for dogs to cats?
it is legal in every case
yes it is, if no authorized product is available and it is not contraindicated by the SPC of that product.
Only if there are no SE in cats
Only in adult cats
yes it is, if no authorized product is available and it is not contraindicated by the SPC of that product.
Which susceptibility method can be used for PK/PD analysis? Disk diffusion method both microdilution none
microdilution
What is metaphylaxis?
A. the admin of medical product to a group of animala before clinical signs of a disease, in order to prevent the occurence of disease or infection
B. the admin of medical product to a group of animal after a diagnosis of clinical disease in part of the group has been established
B. the admin of medical product to a group of animal after a diagnosis of clinical disease in part of the group has been established
Most typical mechanism of action of decreased susceptibility to organophosphates: Increased CYP-enzyme activity Increased efflux Increased transport Increased activity of esterase enzymes
Increased activity of esterase enzymes
Cefquinome belongs to: AMEG A AMEG B AMEG C AMEG D
AMEG B
which statement is true about BRDC?
a. fastidious organism are the most frequent bacteria present. unfortunately, resistance is usually high in them to most AB
b. mycoplasma are the most frequent bacteria present. luckily resistance usually low in them to most AB.
c. fastidious organisms are the most frequent bacteria present, resistance is usually low inn them to ABs.
d. mycoplasma ar the most frequent , unfortunately resistance is usually high .
c. fastidious organisms are the most frequent bacteria present, resistance is usually low inn them to ABs.
Which drug can be effective agaisnt MRSP? cefovecin both mupirocin none
Mupirocin
Which statement is true about the following sentence? Pseudomonas aeruginosa is a frequent causes of suppurative otitis externa, which is sensitive to alkalic environment?
The whole sentence is true
only the second part
only the first part
the whole is false
only the first part
Which statement is true about the following sentence? in case of damanged eardrum, tobramycin and marbofloxacin ear drops can be used, because only polymyxines are ototoxic.
The whole sentence is true
only the second part
only the first part
the whole is false
the whole is false
signle shot products contain: Time dep bactericidal bacteristatic conc dep bactericidal all of them
conc dep bactericidal
Single shot AB can be used against : GI infections foot infection none both
none
sulphonamides are: con dep cidal time dep cidal bacteriostatic none
bacteriostatic
Pradofloxacin are: 1st gen 2nd gen 3rd gen 4th gen
4th gen
Which drug can be used topically to treat canine pyoderma? Azithromycin silver sulfadiazine both none
both
Which drug belongs to the first line systemic treatment of pyoderma? cirpofloxacin both cefalexin none
cefalexin
cirpo- 2ndline
what statement is true about the following sentence? Tris-EDTA is recommended agent in otitis externa, because it has a good antibiofilm effect
all is true
first is true
second part is true
all false
all is true
Valnemulin belongs to: Glycopeptides lincosamide macrolides pleuromutilins
pleuromutilins
pleuromutilins are conc dep cidal time dep cidal none bacteriostatic
bacteriostatic
Which pathogen is most frequent in phayngitis in companion animals?
Streptococci in cats , pasteurella in dogs
Streptococci in dogs, pasteurella in cats
Staphylococcus in cats , pasteurella in dogs
Staphylococcus in dogs , pasteurella in cats
Streptococci in dogs, pasteurella in cats
In which respiratory infection is it necessary to use antibiotics? Calicivirus in cats canine distemper herpes in cats aspergillosis in dogs
canine distemper
does present law allow mixing of AB into feed of animals? no yes only to mix on ab at the time only for pigs
yes
which drug are 1st line of pyoderma? metronidazole both clindamycin none
clindamycin
which drug are 1st line of pyoderma? amox + clav both cefovecin none
both
Route of admin tilmicosin in swine: IM PO both none
PO
Route of admin enrofloxacin in swine: IM PO both none
both
What is true? It is enough to treat supf. pyoderma only topical , because bacteria are only present on the skin surface in this case. Only the first is true only second is true all true all false
all false
What is recommended treatment duration in feline rhinotracheitis? 7-10 days in acute, 1-2w in chronic 7-10 days in acute, 4-6w in chronic acute never, chronic 4-6w acute never, chronic 1-2w
acute never, chronic 4-6w
Strepto and pasteurella frequently causes... in companion animals: Bronchitis, pneumonia rhinitis, sinusitis pharyngitis, tonsilitis all
all
How can we prevent ab resistance:
Use ab for treatment, not prevention
Must know pharmacodynamics of antibacterial agents
Perform antibiotic susceptibility test regularly
All
all
Route of amox + clav for Swine: PO IM both none
both
What route of admin - cefquinome in swine?
PO
IM
both none
IM
What route of admin - marbofloxacin in swine? PO IM both none
both
What is true:
a. rhinitis is more freq caused by virus, but bacterial superinfection always occur, so ab prophylaxis is used.
b. rhinitis is more freq caused by virus, so in many cases ab treatment is not necessary.
c. fungi are the most freq cause, but these are selflimiting, so anti fungal treatment is not necessary.
d. most cases of rhinitis is caused by bacteria, streptococci,staphylococci, pasteurella, but these are self-limiting , supportive therapy is sufficient.
b. rhinitis is more freq caused by virus, so in many cases ab treatment is not necessary.
Resistance rates are the worst in this species: poultry swine ruminants dogs
swine
Cefquinome belongs to: AMEG A AMEG B AMEG C AMEG D
B
for how long shall be valid a veterinary prescription for antimicrobial veterinary medicinal product from the date of its issue according to the new EU regulation of veterinary medicines?
10d
5d
30d
its validity shall not be limited
5d
Topical for pyoderma: enrofloxacin neomycin both none
neomycin
Florfenicol can have this side effect in dogs: KCS Anaemia both none
Anaemia (bone marrow suppression)
KCS = PotSA
what is true: Usually there’s a background disease behind pyoderma, commonly allergy or parasite infection.
all true
all false
first true
second true
all true
what is true: Usually systemic is not needed in case of intertrigo, bacause bacteria cannot reach deeper parts of of the skin in this diseases.
all true
all false
first true
second true
all true
what is true:
Consumption of fluoroquinolones should be decreased
Consumption of colistin should be decreased
both
none
both (decreased)
what is general indication?
a. The product is indicated against e.coli
b. the indication says that the product is indicated against bacteria that are sensitive to AB
c. the product is indicated for several bacteria which are listed in the indication
d. in the indication of the product only the name of genus is included.
c. the product is indicated for several bacteria which are listed in the indication ??
what is true?
Ceftiofur-HCl is turned to desfuroyl-ceftiofur slowly in the body
Ceftiofur-HCl is turned to ceftiofur crystalline free acid quickly in the body
Ceftiofur-HCl is turned to desfuroyl-ceftiofur quickly in the body
Ceftiofur-HCl is turned to ceftiofur crystalline free acid slowly in the body.
Ceftiofur-HCl is turned to desfuroyl-ceftiofur quickly in the body
This drug is very effective against fastidious bacteria and mycoplasma as well and has excellent distribution. Tildipirosin both gamithromycin none
Gamithromycin
what is true about foot disease in ru?
a. interdigital phlegmone, topical antibiotic therapy is enough, while interdigital dermatitis needs systemic therapy.
b. both are enough to be treated with local AB and systemic NSAIDs
c. interdigital dermatitis, topical antibiotic therapy is enough, while interdigital phlegmone needs systemic therapy.
d. both need to be treated with systemic AB and NSAIDs
c. interdigital dermatitis, topical antibiotic therapy is enough, while interdigital phlegmone needs systemic therapy. ?
amox + clav are: AMEG A AMEG B AMEG C AMEG D
AMEG C
Used for foot rot that are good against anaerobic bacteria and penetration is good: lincomycin florfenicol both none
both
First choice in CIRDC: Doxycycline Clarithromycin both none
both
First choice in CIRDC: Doxycycline PotSA both none
both
this drug is not authorized for poultry in EU: chloramphenicol tiamulin tylvalosin phenoxymethylpenicillin
chloramphenicol
Which of the following bacteria can not produce beta lactamase enzymes? Staphylococcus aureus e.coli pasteurella multicida streptococcus suis
streptococcus suis?
recommended in dog pneumonia: Doxycycline + gentamicin amox + clav + gentamicin both none
amox + clav + gentamicin
not authorized in EU (poultry): amox + clav spectinomycin difloxacin colistin
CLAV!
in poultry, stahylococcus cause: septicaemia upper respiratory tract disease both none
Septicaemia
recommended in dog pneumonia: amox clav + cefuroxime amox clav + enrofloxacin both none
amox clav + enrofloxacin
not authorized in EU (poultry): gentamicin doxycycline lincomycin florfenicol
florfenicol
which of the following bacteria can cause polyserositis of swine? mycoplasma hyopneumoniae e.coli m.suis streptococcus suis
streptococcus suis
Pathogens of CIRDC: Bordetella bronchiseptica parainfluenza virus both none
both
How should ab be administered in case of pneumonia in dogs? SC IV Orally inhalationally
IV
in poultry, staphylococcus aureus can cause: arthritis dermatitis both none
both
which agent is most effective in shampoos for cellulitis? ethyl lactate prioctone olamine benzoyl peroxide chlorine dioxide
benzoyl peroxide
How should amikacin be used to treat canine pyoderma? oral im both none
im
which drug combination would be recommended in aspiration pneumonia in dogs? amox + cefuroxime + metronidazole Amox + marboflox + metronidazole both none
none
Broad spectrum beta-lactam + enrofloxacin (aminoglycoside) + metronidazole against anaerob
Metronidazole belongs to nitrofurans monobactams nitroimidazoles carbapenems
nirtoimidazole
Effective agaisnt fastidious bacteria and mycoplasma as well and has excellent distribution: enrofloxacin tulathromycin both none
both
which ab reach high conc intracellularly? penicillins cephalosporins macrolides all
macrolides
