AB in Companion Animals Flashcards
Do you need systemic treatment in surface pyoderma?
no, local
Do you need systemic treatment in superficial pyoderma?
topical as a start, usually need systemic also
Pathogenic bacteria in pyoderma:
Staphylococcus pseudointermedius S.aureus + streptococcus cani S.pseudomedius E.coli P.aeruginosa
1st choice treatment of pyoderm caused by P.pseudointermedius :
Cephalosporin, cephalexin.
Amox + clav can also be.
Why don’t we use penicillinase stable AB inpyoderm caused by P.pseudointermedius :
not good orally
Drug for pyoderma that can be used against MRSA, MRSP:
Mupirocin - local
Fusidic acid when mupirocin is not available
what are the AB that can be used emperically in pyoderma: (1st line)
1st gen cephalosporins - cephalexin Amox+clav 3rd cephalosporins - cefovecin (CIA..) Lincosamides - clindamycin PotSA - Sulfamethoxazol + TMP
2nd line drugs of pyoderma (only after susceptibility test):
Fluoroquinolones:
2nd gen : Enro, Marbo, Cipro - best
4th gen : Pradofloxacin - Last choice!
Which bacteria is ciprofloxacin very good against (pyoderma):
against strept, staphylococcus, pseudomonas, e.coli
Local drugs against MRSP, MRSA (pyoderma):
Mupirocin, fusidic
Combinations should be used because of one step mutations
systemic drugs against MRSP, MRSA (pyoderma):
Rifampicin (combination) - hepatotox (give protectants)
Amikacin - nephrotox
Florfenicol - not convenient here (some countries have chloramphenicol)
3rd line treatment of pyoderma:
remember always susceptibility test!!!!
Macrolides - Azithromycin, clarithromycin
AMEG A - vancomycin, teicoplanin, linezolid
nephrotox, never in FPA
If you were to give a pyoderma treatment to a dog and the dog needed to be on the drugs for 5 weeks, how many weeks should the dog be on the treatment?
6 weeks!!!! Always one week more of recovery !!!!
Is systemic treatment needed for otitis externa?
not without complications
Is systemic treatment needed for otitis media?
yes