passmed Flashcards
what medical condition can give a falsely low HbA1c
sickle cell anaemia
what medical condition can give a falsely high HbA1c
splenectomy
Howell-Jolly bodies and siderocytes
hyposplenism
treatment after having a venous thromboembolism
Venous thromoboembolism - length of warfarin treatment
-provoked (e.g. recent surgery): 3 months
-unprovoked: 6 months
antibiotic of choice for neutropenic sepsis
Piperacillin with tazobactam (Tazocin)
isolated thrombocytopenia (low platelets)
immune thrombocytopenic prupura
management of von willebrand
tranexamic acid for mild bleeding
desmopressin (DDAVP): raises levels of vWF by inducing release of vWF from Weibel-Palade bodies in endothelial cells
factor VIII concentrate
mechanism of action of rivaroxaban
direct factor Xa inhibitor
rate of transfusion of RBCs for a non-urgent scenario
over 2 hours
raised HbA2?
beta thalassaemia trait
Deranged coagulation in sepsis
DIC
which blood product has the highest risk of bacterial contamination
platelets
antibiotic of choice for neutropenic sepsis
Piperacillin with tazobactam (Tazocin)
cause of sudden fall in Hb in someone with sickle cell
aplastic crisis
what causes aplastic crisis
infection with parovirus