Passage Tidbits To Remember Flashcards
All viruses gain entry into the cell through_____
Recognition of cell-surface proteins by viral proteins
Why would tumor cells be more likely by affected by a gene that disrupts DNA replication?
Because tumor cells divide mitotically at a faster rate than normal cells
How might Antibodies act against foreign particles?
- May cost a foreign particle so that it is taken up by phagocytic cells
- May bind to a foreign particle, interfering with its function
- May elicit a cascade leading to the lysis of foreign cells
Cells not actively dividing
T cell (must be stimulated by antigen and appropriate chemical signals to begin proliferating)
RBC
Neuron
of high energy phosphate bonds per amino acids =
4n - 1
n= number of amino acids in the peptide
Are N-terminal AA formylated in prokaryotes?
Yes
How many different 70S densities can be found when bacteria is allowed to grow/ do protein synthesis?
Ribosomes dissociate between rounds of translation. There would be some all-light ribosomes, some all-heavy, some with 30S light/50 S heavy units, some with 50S light/30S heavy units
4 different densities
What is essential for translation?
Hydrogen bonds between tRNA and mRNA
Can proteins spontaneously retold following denaturation?
No
What protein-protein interactions allow prion aggregation?
Tertiary and Quaternary
Shine-Dalgarno sequences
Ribosome binding site in Prokaryotic RNA
Would not be found in eukaryotes
Prions
Highly stable aggregates of misfolded protein Highly resistant to proteolysis Self replicating Long incubation period Destruction of neurons
Viroids
Single-stranded small circular RNA Self complementarity Lack capsids Catalytic, produce siRNA RNA-dependent RNA polymerase
Lymph nodes
site of B cell and T cell proliferation
saponification of triglycerides yields:
glycerol
fatty acid salts
Which mutation would be most likely to convert a proto-oncogene into an oncogene?
Missense
b/c it doesn’t really change the protein function but does cause a mutation
amphoteric
act as an acid/base
amphiphatic
hydrophobic/hydrophilic
What type of muscle is the diaphragm?
skeletal
what is the role of small ribosomal unit?
initiate translation by recognition of t-Met
Which primer is most suitable for PCR?
suitable primers have high GC content and have G or C base pairs at 5’ and 3’ ends
What type of proteins are used during protein synthesis?
L-amino acids
What happens to protein synthesis when you add D-amino acid?
inhibited
If the GAPDH gene is continuously expressed, where is it most likely found?
in euchromatin
