Parvoviridae Flashcards
Non enveloped
Parvoviridae
What does Latin word parvus ?
Small
Smallest DNA animal virus
Parvoviridae
Replication occurs only in ___________
actively dividing cells
It takes place
in the nucleus of the infected
cell
capsid assembly
It replicates in immature
erythroid cells and causes
several adverse
consequences, including
aplastic crisis, fifth disease,
and fetal death
Human parvovirus B19
Erythema infectiosum host/condition
Children (fifth disease)
Adult
Transient aplastic crisis host/condition
Underlying hemolysis
Pure red cell aplasia host/condition
Immunodeficiencies
Hydrops fetalis Host/condition
Fetus
Erythema infectiosum clinical features
- Cutaneous rash
- Arthralgia - arthritis
Transient aplastic crisis clinical features
Severe acute anemia
Pure red cell aplasia clinical features
Chronic anemia
Hydrops fetalis clinical features
Fatal anemia
These are treated
symptomatically.
Severe anemia due to
the latter may require
transfusion therapy
Fifth disease and
transient aplastic crisis
