Herpesviridae Flashcards
The name refers to Latin herpes
Creep
describing the spreading
nature of skin lesions caused by these viruses
Herpes
infect epithelial cells and establish
latent infections in neurons.
HSV-1 and HSV-2
classically associated with oropharyngeal
lesions and causes recurrent attacks of fever
blisters.
Type 1
primarily infects the genital mucosa and is
mainly responsible for genital herpes, though the
anatomical specificity of these viruses is diminishing.
Type 2
the leading viral cause of sporadic
encephalitis in the United States.
HSV-1
It can cause neonatal infections that
are often severe.
Both types 1 and 2
causes chickenpox (varicella) on primary infection
and establishes latent infection in neurons.
VZV
associated with the development of Kaposi
sarcoma, a vascular tumor that is common in patients
with AIDS
HHV-8
also a T-lymphotropic virus, has not yet been
definitively linked to any specific disease.
HHV-7
replicates in epithelial
cells of the oropharynx and
parotid gland and establishes
latent infections in
lymphocytes
EBV
replicates in epithelial cells of the respiratory tract,
salivary glands, and kidneys and persists in lymphocytes
CMV
an important cause of congenital defects,
neonatal hearing loss, and mental retardation.
CMV
CMV stands for
Cytomegalovirus
EBV stands for
Epstein-Barr virus
