Parvo

Question 1

Risk of infection if exposure at home, school or community

Answer 1

Home: 50%
school: 20-30%
Community: up to 20%

Question 2

Outcomes with proven maternal infection

Answer 2

10% fetal loss in first 20/40
3% hydrops (9-20)
<1% (no excess or consistent pattern). Congenital abnormalities
15% risk of hydrops < 20/40, <5%> 20/40

Question 3

Risk of maternal -fetal transmission

Answer 3

50%

Question 4

IgG pos

IgM neg

Answer 4

Immune

Nil action required

Question 5

IgG neg

IgM neg

Answer 5

Susceptible

Repeat IgG 2-4 weeks after exposure or if symptoms

Question 6

IgG neg

IgM pos

Answer 6

?Recent infection

Retest. IgG in 2–4 weeks

Question 7

IgG pos

IgM pos

Answer 7

Recent infection
Depends on gestation for management, bu if <20/40, USS at 1-2 week intervals for 12 weeks
If. Signs of fetal Anaemia then transfuse
If. Nothing after 30/40 - no further action

Question 8

Parvo surveillance

Answer 8

Arrange USS if acute Parvo in first 20/40 -1-2 weekly for up to 8-12/40 after infection
Median time to hydrops is 3 weeks
Inutero transfusion if MCA PSV >1.5MOM (fetal anaemia