GBS Flashcards
1
Q
Obstetric risk factors for GBS (early onset)
A
Previous infant with EOGBS GBS bacteruria this pregnancy Spontaneous onset of labour < 37 ROM > 18 hours Intrapartum fever >38 Known carriage of GBS in current pregnancy Chorioamnionitis clincally Other twin with current EOGBS
2
Q
Universal screening (35-37)
A
LVS + anorectal swabs
Selective enrichment broth medium
If negative, still need IV Abx in labour if has had previous infant with GBS or GBS bacteruria in this pregnancy
3
Q
Aus intrapartum chemoprophylaxis with no signs of sepsis
A
Benpen 3g IV load, then 1.8g. Q4H
If pen allergic, clindamycin 600mg IV Q8H OR vbac 1g IV Q12h
4
Q
Intrapartum IVAbx with signs of sepsis
A
amox 2 g IV Q6H, gent 4-6mg/kg, metro 500mg IV Q12H
5
Q
Invx in labour if signs of mat sepsis
A
Endocervical swab Urine Blood cultures FBC CRP
6
Q
Pathogens responsible for chorio
A
GBS
Anaerobic cocci
Gram - bacilli
7
Q
Outcomes for mother and baby
A
Maternal sepsis Stillbirth Preterm birt Neonatal encephalopathy Neonatal sepsis (Pneumonia, meningitis) Long term sequels
8
Q
NNT to prevent 1 case of EOGBS
A
1700
24-32000 to prevent one death
