Parturition Flashcards
Covers: Initiation of Parturition 1/2; Stages of Parturition
What fetal endocrine axis is required for triggering the onset of parturition?
(The fetal hypothalamic-pituitary-adrenal/HPA axis)
What does space limitation stimulate in the fetus that eventually induces parturition?
(ACTH secretion by the fetal pituitary)
What triggers the fetal pituitary to start producing ACTH which then triggers parturition?
(Space limitation, triggers parturition through the cortisol released from the adrenals in response to the ACTH)
What effect does fetal cortisol have on the progesterone and estrogen levels in the mother?
(Induces the enzymes that form progesterone to instead start making estrogen so progesterone levels fall while estrogen levels rise; also triggers the release of PGF to lyse any luteal structures to further reduce progesterone)
Decreasing what hormone removes the block it has on uterine contractions and is a necessary step for the initiation of parturition?
(Progesterone)
The rising levels of estrogen close to parturition induce an increase in receptors to what hormone in the reproductive tract?
(Oxytocin receptors)
What hormones are important for pelvic ligament relaxation (presents as gluteal muscles sinking, tailhead becoming more prominent, and sacrosciatic ligament softening) and expansion of the birth canal? Two answers.
(Relaxin and estrogen)
Fetal cortisol is not only important for triggering parturition, it also is important for final maturations of what structure in the fetus?
(The lungs, specifically cortisol enhances surfactant production which is important for the babies first breath)
What hormone is important for synthesis versus ejection of milk from the dam?
(Prolactin is important for synthesis and oxytocin is important for letdown)
What is the location of the chorioallantoic membrane in the first stage of parturition?
(It is entering the vagina at this time)
What occurs to the chorioallantoic membrane in the second stage of parturition?
(It ruptures after the fetus enters the birth canal)
What is the purpose of the uterine contractions in the first stage of parturition (which are mediated by oxytocin, PGF, and estrogen)?
(Aids the fetus in adopting the birthing posture)
A failure of what reflex related to parturition can result in dystocia?
(Ferguson reflex → failure of the cervix to dilate may result from malpositioning of the fetus or conditions that prevent stimulation of the ferguson reflex)
What is the status of the cervix during the second stage of parturition?
(Cervix will be completely dilated)
What other contractions join the uterine contractions in the second stage of parturition?
(Abdominal contractions)
Which stage of parturition does placental dehiscence, separation, and expulsion occur within?
(The third stage of parturition)
Which of the stages of parturition is the longest?
(The first stage)
Change in temperature as a way to predict parturition is most commonly used in what species?
(Dogs, will see a drop to 98-9.5 degrees F)